Low-density lipoprotein size, highdensity lipoprotein concentration, and endothelial dysfunction in non-insulindependent diabetes

Diabetic Medicine

Volumn 14, Issue 11, 1997, Pages 974-978

  O'Brien, S F ^a   Watts, G F ^a,c   Playford, D A ^a   Burke, V ^a   O'Neal, D N ^b   Best, J D ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL PERTH HOSPITAL   (Australia)

Author keywords

Diabetes; Endothelial function; HDL cholesterol; LDL particle size; Nitric oxide

Indexed keywords

ACETYLCHOLINE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ARTICLE; BLOOD VESSEL TONE; CLINICAL ARTICLE; FOREARM BLOOD FLOW; HUMAN; LIPOPROTEIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; SMOOTH MUSCLE CONTRACTILITY; VASCULAR SMOOTH MUSCLE; VEIN OCCLUSION PLETHYSMOGRAPHY;

ACETYLCHOLINE; ADULT; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; FOREARM; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; NITROPRUSSIDE; PARTICLE SIZE; PLETHYSMOGRAPHY; REGRESSION ANALYSIS;

EID: 0030782093     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9136(199711)14:11<974::AID-DIA495>3.0.CO;2-I     Document Type: Article

References (30)

1. Pyörälä K, Laakso M, Uusitupa M. Diabetes and atherosclerosis: an epidemiological view. Diabetes Metab Rev 1987; 3: 463-524.
2. Flavahan NA. Atherosclerosis or lipoprotein-induced endothelial dysfunction: potential mechanisms underlying reduction in EDRF/nitric oxide activity. Circulation 1992; 85: 1927-1938.
3. Briner VA, Lüscher TF. Role of vascular endothelial abnormalities in clinical medicine: atherosclerosis, hypertension, diabetes, and endotoxaemia. Adv Int Med 1994; 39: 1-22.
4. Steinberg HO, Chaker H, Learning R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97: 2601-2610.
5. Cohen RA. Dysfunction of vascular endothelium in diabetes mellitus. Circulation 1993; 87 (suppl V): V67-V76.
6. Jaap AJ, Tooke JE. Pathophysiology of microvascular disease in non-insulin dependent diabetes mellitus. Clin Sci 1995; 89: 3-12.
7. Watts GF, O'Brien SF, Silvester W, Millar JA. Impaired endothelium-dependent and independent dilatation of forearm resistance arteries in men with diet-treated non-insulin-dependent diabetes: role of dyslipidaemia. Clin Sci 1996; 91: 567-573.
8. Taskinen MR. Hyperlipidaemia in diabetes. Clin Endocrinol Metab 1990; 4: 743-775.
9. Feingold KR, Grunfeld C, Pang M, Doerrier W, Krauss RM. LDL subclass phenotypes and triglyceride metabolism in non-insulin-dependent diabetes Arterioscler Thromb 1992; 12: 1496-1502.
10. Krauss RM. Heterogeneity of plasma low-density lipoproteins and atherosclerosis risk. Curr Opin Lipidol 1994; 5: 339-349.
11. Tribble DL, Holl LG, Wood PD, Krauss RM. Variations in oxidative susceptibility among six low density lipoprotein subfractions of differing density and particle size. Atherosclerosis 1992; 93: 189-199.
12. Austin MA, King MC, Vranizan KM, Krauss RM. Atherogenic lipoprotein phenotype: a proposed genetic marker for coronary heart disease risk. Circulation 1990; 82: 495-506.
13. Watts GF, Mandalia S, Brunt JNH, Slavin BM, Coltart DJ, Lewis B. Independent associations between plasma lipoprotein subfraction levels and the course of coronary artery disease in the St Thomas' Atherosclerosis Regression Study. Metabolism 1993; 42: 1461-1467.
14. Whitney RJ. The measurement of volume changes in human limbs. J Physiol 1953; 121: 1-27.
15. Greenfield ADM, Patterson GC. Reactions of the blood vessels of the human forearm to increase in transmural pressure. J Physiol 1954; 125: 508-524.
16. Chung BH, Segrest JP, Ray MJ, Brunzell JD, Hokanson JE, Krauss RM, Beudrie K, Cone JT. Single vertical spin density gradient ultracentrifugation. In: Segrest JP, Albert JJ, eds. Methods in Enzymology. New York: Academic Press, 1986: 128: 341-344.
17. Krauss RM, Burke DJ. Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J Lipid Res 1982; 23: 97-104.
18. O'Neal ON, Lee P, Murphy B, Best JO. Low density lipoprotein particle size distribution in end stage renal disease treated with haemodialysis or peritoneal dialysis. Am J Kid Dis 1996; 27: 84-91.
19. McVeigh GE, Brennan GM, Johnstone GO. McDermott BJ, McGrath LT, Henry WR, et al. Impaired endothelium-dependent and independent vasodilatation in patients with Type 2 (non-insulin dependent) diabetes mellitus. Diabetologia 1992; 35: 771-776.
20. Williams SB, Cuseo JA, Roddy MA, Johnstone MT, Creager MA. Impaired nitric oxide-mediated vasodilatation in patients with non-insulin dependent diabetes mellitus. J Am Coll Cardiol 1996; 27: 567-574.
21. Goodfellow J, Ramsey MW, Luddington LA, Jones CJM, Coates PA, Dunston F, et al. Endothelium and inelastic arcteries: an early marker of vascular dysfunction in non-insulin dependent diabetes. Br Med J 1996; 312: 744-745.
22. MacKness MI, Abbott CA, Arrol S. Durrington PN. The role of high-density lipoprotein and lipid-soluble antioxidant vitamins in inhibiting low-density lipoprotein oxidation. Biochem J 1993; 294: 829-835.
23. Gugliano D, Ceriello A, Paolisso G. Oxidative stress and diabetic vascular implications. Diabetes Case 1996; 19: 257-267.
24. Bucala R, Tracey KJ, Cerami A. Advanced glycosylation products quench nitric oxide and mediate endothelium- dependent vasodilatation in experimental diabetes. J Clin Invest 1991; 87: 432-438.
25. Woolfson RG, Poston L. Effect of NG-monomethyl-L-arginine on endothelium dependent relaxation of human subcutaneous resistance arteries. Clin Sci 1990; 79; 273-278.
26. Gailard CJ, McPherson GA. Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery. Br J Pharmacol 1992; 105: 429-435.
27. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-216.
28. Katusic ZS. Nitric oxide: regulator of P-selectin expression. Gastroenterology 1994; 107: 1199-1201.
29. Nitenberg A, Valensi P, Sachs R, Dali M, Aptecar E. Attali J. Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes 1993; 42: 1017-1025.
30. Lamarche B, Tchernof A, Moorjani S, Cantin B, Dagenais G, Lupien PJ, Després JP. Small, dense low-density lipoprotein particles as a predictor of the risk of ischaemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Circulation 1997; 95: 69-75.