The effect of castanospermine on the metastatic properties of prostate cancer cells

Anticancer Research

Volumn 17, Issue 5 A, 1997, Pages 3659-3663

  Yee, C S ^a   Schwab, E D ^a   Lehr, J E ^a   Quigley, M ^a   Pienta, K J ^a,b  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

AT.1; Castanospermine; MAT LyLu; Metastasis; Prostate cancer; Rat

Indexed keywords

CASTANOSPERMINE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL MOTILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; METASTASIS; METASTASIS INHIBITION; METASTASIS POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RAT;

ADENOCARCINOMA; ANIMALS; CELL SURVIVAL; INDOLIZINES; MALE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHAGOCYTOSIS; PROSTATIC NEOPLASMS; RATS; TUMOR CELLS, CULTURED;

EID: 0030781986     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Ostrander GK, Scribner K and Rohrschneider LR: Inhibition of v-fms-induced tumor growth in nude mice by castanospermine. Canc Res 48: 1091-1094, 1988.
2. Humphries MJ, Matsumoto K, White SL and Olden K: Inhibition of experimental metastasis by castanospermine in mice: Blockage of two distinct stages of tumor colonization by oligosaccharide processing inhibitors. Canc Res 46: 5215-5222, 1986.
3. Spearman MA, Damen JE, Kolodka T, Greenberg AH, Jamieson JC, and Wright JA: Differential effects of glycoprotein processing inhibiton on experimental metastasis formation by T-24-H-ras transformed fibroblasts. Canc Lett 57: 7-13, 1991.
4. Spearman MA, Ballon BC, Gerrard JM, Greenberg AH and Wright JA: The inhibition of platelet aggregation of metastatic H-ras-transformed 10T1/2 fibroblasts with castanospermine, an N-linked glycoprotein processing inhibitor. Canc Lett 60: 185-191, 1991.
5. Isaacs, JT, Isaacs, WB, Wouter, FJF, and Scheres, J: Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities in prostate cancers. The Prostate 9: 261-281, 1986.
6. Albrecht-Buehler, G: The phagokinetic tracks of 3T3 cells. Cell 11: 395-404, 1977.
7. Pili R, Chang J, Partis R, Mueller RA, Chrest FJ and Passaniti A: The α-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth. Canc Res 55: 2920-2926, 1995.