Effect of lecithinized-superoxide dismutase on the interstitial pneumonia model induced by bleomycin in mice

Japanese Journal of Pharmacology

Volumn 75, Issue 1, 1997, Pages 97-100

  Yamazaki, Chihiro ^a   Hoshino, Jiro ^a   Hori, Yusuke ^a   Sekiguchi, Tomoko ^a   Miyauchi, Satoshi ^a   Mizuno, Syoji ^a   Horie, Katsuyuki ^a  

^a SEIKAGAKU CORPORATION   (Japan)

Author keywords

Bleomycin; Interstitial pneumonia; Lecithinized superoxide dismutase

Indexed keywords

BLEOMYCIN; COPPER ZINC SUPEROXIDE DISMUTASE; HYDROXYPROLINE; PHOSPHATIDYLCHOLINE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; INTERSTITIAL PNEUMONIA; INTRAVENOUS DRUG ADMINISTRATION; LUNG FIBROSIS; MALE; MOUSE; NONHUMAN;

EID: 0030781269     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.75.97     Document Type: Article

References (15)

1. Strausz J, Müller-Quernheim J, Steppling H and Ferlinz R: Oxygen radical production by alveolar inflammatory cells in idiopathic pulmonary fibrosis. Am Rev Respir Dis 141, 124-128 (1990)
2. Mizushima Y, Igarashi R, Hoshi K, Sim AK, Cleland ME, Hayashi H and Goto J: Marked enhancement in anti-thrombotic activity of isocarbacyclin following its incorporation into lipid microspheres. Prostaglandins 33, 161-168 (1987)
3. Mizushima Y and Igarashi R: Studies on polypeptide drug delivery system: tissue distribution of immunoglobulin G conjugated with lecithin. J Controlled Release 17, 99-104 (1991)
4. Igarashi R, Hoshino J, Takenaga M, Kawai S, Morizawa Y, Yasuda A, Otani M and Mizushima Y: Lecithinization of superoxide dismutase potentiates its protective effect against Forssman antiserum-induced elevation in guinea pig airway resistance. J Pharmacol Exp Ther 262, 1214-1219 (1992)
5. Igarashi R, Hoshino J, Ochiai A, Morizawa Y and Mizushima Y: Lecithinized superoxide dismutase enhances its pharmacologic potency by increasing its cell membrane affinity. J Pharmacol Exp Ther 271, 1672-1677 (1994)
6. Ikeda K, Kinoshita M, Iwasaki N, Tagaya N and Shiojima T: Lecithinized superoxide dismutase retards wobbler mouse motoneuron disease. Neuromuscul Disord 5, 383-390 (1995)
7. Hori Y, Hoshino J, Yamazaki C, Sekiguchi T, Miyauchi S, Mizuno S and Horie K: Effect of lecithinized-superoxide dismutase on the rat colitis model induced by dextran sulfate sodium. Jpn J Phamacol 74, 99-103 (1997)
8. Nakauchi K, Ikata T, Katoh S, Hamada Y, Tsuchiya K and Fukuzawa K: Effect of lecithinized superoxide dismutase on rat spinal cord injury. J Neurotrauma 13, 573-582 (1996)
9. Woessner LF: The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 93, 440-447 (1961)
10. Ekimoto H, Takahashi K, Matsuda A and Umezawa H: Animal model on BLM-induced pulmonary fibrosis -comparison of the systemic (intraperitoneal) administration with the local (intratracheal) instillation-Jpn J Cancer Chemother 10, 2550-2557 (1983)
11. Yasui M: Effect of the administration of interleukin-1 in vivo on bleomycin-induced pneumonitis in mice. Juzen Med Soc 103, 425-440 (1994)
12. Slosman DO, Costabella PM, Roth M, Werlen G and Polla BS: Bleomycin primes monocytes-macrophages for superoxide production. Eur Respir J 3, 772-778 (1990)
13. Conley NS, Yarbro JW, Ferrari HA and Zeidler RB: Bleomycin increases superoxide anion generation by pig peripheral alveolar macrophages. Mol Pharmacol 30, 48-52 (1986)
14. Mon H, Tanaka H, Kawada K, Nagai H and Koda A: Suppressive effects of tranilast on pulmonary fibrosis and activation of alveolar macrophages in mice treated with bleomycin: role of alveolar macrophages in the fibrosis. Jpn J Pharmacol 67, 279-289 (1995)
15. Beckman JS, Beckman TW, Chen J, Marshall PA and Bruce AF: Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87, 1620-1624 (1990)