Analysis of the E-cadherin and P-cadherin promoters in murine keratinocyte cell lines from different stages of mouse skin carcinogenesis

Molecular Carcinogenesis

Volumn 20, Issue 1, 1997, Pages 33-47

  Faraldo, María Luisa M ^a,c   Rodrigo, Isabel ^a   Behrens, Jurgen ^b   Birchmeier, Walter ^b   Cano, Amparo ^a,d  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c INSTITUT CURIE   (France)

^d CSIC   (Spain)

Author keywords

Cadherin expression; Nuclear factors; Regulatory elements; Tumor progression

Indexed keywords

CADHERIN; CADHERIN P; CIS ACTING ELEMENT; DNA; NUCLEAR FACTOR; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; CELL TYPE; CONFERENCE PAPER; CONTROLLED STUDY; DNA FOOTPRINTING; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; SKIN CARCINOGENESIS; SPINDLE CELL; TUMOR GROWTH;

ANIMALS; BASE SEQUENCE; CADHERINS; CELL LINE; DNA FOOTPRINTING; DNA, NEOPLASM; DOWN-REGULATION; KERATINOCYTES; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; SKIN NEOPLASMS; TRANSCRIPTION FACTORS;

ANIMALIA; MURINAE;

EID: 0030778285     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199709)20:1<33::AID-MC5>3.0.CO;2-J     Document Type: Conference Paper

References (51)

1. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-1455, 1991.
2. Birchmeier W, Behrens J. Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness Biochim Biophys Acta 1198:11-26, 1994.
3. Kemler R. Classical cadherins. Semin Cell Biol 3:149-155, 1992.
4. Hyafil F, Morello D, Babinet C, Jacob F. A cell surface glycoprotein involved in the compaction of embryonic carcinoma cells and cleavage stage embryos. Cell 21:927-934, 1980.
5. 2+-dependent cell adhesion. EMBO J 6:3647-3653, 1987.
6. Yoshida-Noro C, Suzuki N, Takeichi M. Molecular nature of the calcium-dependent-cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Dev Biol 101:19-27, 1984.
7. Nose A, Takeichi M. A novel cadherin cell adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos. J Cell Biol 103:2649-2658, 1986.
8. Hatta K, Nose A, Nagafuchi A, Takeichi M. Cloning and expression of cDN-encoding a neural calcium-dependent cell adhesion molecule: Its identity in the cadherin gene family. J Cell Biol 106:873-881, 1988.
9. Gallin WJ, Edelman GM, Cunningham BA. Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells. Proc Natl Acad Sci USA 80:1038-1042, 1983.
10. Takeichi M. The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis. Development 102:639-655, 1988.
11. Fujita M, Furukawa F, Fujii K, Horiguchi Y, Takeichi M, Imamura S. Expression of cadherin cell adhesion molecules during human skin development: Morphogenesis of epidermis, hair follicles and eccrin sweat ducts. Arch Dermatol Res 284:159-166, 1992.
12. Takeichi M. Cadherins in cancer: Implications for invasion and metastasis. Curr Opin Cell Biol 5:806-811, 1993.
13. Shimoyama Y, Hirohashi S, Hirano S, et al. Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas Cancer Res 49:2128-2133, 1989.
14. Shimoyama Y, Hirohashi S. Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 51:2185-2192, 1991.
15. Navarro P, Gómez M, Pizarro A, Gamallo C, Quintanilla M, Cano A. A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol 115:517-533, 1991.
16. +-adenosine triphosphate during mouse skin tumor progression. Am J Pathol 140:1179-1185, 1992.
17. Cano A, Gamallo C, Kemp CJ, et al. Expression pattern of the cell adhesion molecules E-cadherin, P-cadherin and α6β4 integrin is altered in pre-malignant skin tumors of p53-deficient mice. Int J Cancer 65:254-262, 1996.
18. Ringwald M, Baribault H, Schmidt C, Kemler R. The structure of the gene coding for the mouse cell adhesion molecule uvomorulin. Nucleic Acids Res 19:6533-6539, 1991.
19. Hatta M, Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA. Takeichi M. Genomic organization and chromosomal mapping of the mouse P-cadherin gene. Nucleic Acids Res 19:4437-4441, 1991.
20. Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M. Genomic structure and chromosomal mapping of the mouse N-cadherin gene. Proc Natl Acad Sci USA 89:8443-8447, 1992.
21. Sorkin BC, Hemperley JJ, Edelman GM, Cunningham BA. Structure of the gene for the liver cell adhesion molecule, L-CAM. Proc Natl Acad Sci USA 85:7617-7621, 1988.
22. Behrens J, Löwrick O, Klein-Hitpass L, Birchmeier W. The E-cadherin promoter: Functional analysis of the GC-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci USA 88:11495-11499, 1991.
23. Bussemakers MJ, Giroldi LA, van Bokhoven A, Schalken JA. Transcriptional regulation of the human E-cadherin gene in human prostate cell lines: Characterization of the human E-cadherin promoter. Biochem Biophys Res Commun 203:1284-1290, 1994.
24. Hennig G, Behrens J, Truss M, Frisch S, Reichmann E, Birchmeier W. Progression of carcinoma cells is associated with alterations in chromatic structure and factor binding at the E-cadherin promoter in vivo. Oncogene 11:475-484, 1995.
25. Hennig G, Löwrick O, Birchmeier W, Behrens J. Mechanism identified in the transcriptional control of epithelial gene expression. J Biol Chem 271:595-602, 1996.
26. Sorkin BC, Jones FS, Cunningham BA, Edelman GM. Identification of the promoter and a transcriptional enhancer of the gene encoding L-CAM, a calcium-dependent cell adhesion molecule. Proc Natl Acad Sci USA 90:11356-11360, 1993.
27. Goomer RS, Holst BD, Wood IC, Jones FS, Edelman GM. Regulation in vitro of an L-CAM enhancer by homeobox genes HoxD9 and HNF-1. Proc Natl Acad Sci USA 91:7985-7989, 1994.
28. Hatta M, Takeichi M. Complex cell type-specific transcriptional regulation by the promoter and an intron of the mouse P-cadherin gene. Development Growth & Differentiation 36:509-519, 1994.
29. Faraldo MLM, Cano A. The 5′ flanking sequences of the mouse P-cadherin gene. Homologies to 5′ sequences of the E-cadherin gene and identification of a first 215 base-pair intron. J Mol Biol 231:935-941, 1993.
30. Di′az-Guerra M, Haddow S, Bauluz C, et al. Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harbouring Harvey ras gene alterations. Cancer Res 52:680-687, 1992.
31. Nordeen SK. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6:454-457, 1988.
32. Gorman CM, Merlino GT, Willingham MC, Pastan I, Howard BH. The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety or eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci USA 79:6777-6781, 1982.
33. Boshart M, Weber F, Jahn G, Dorsh-Häsler K, Fleckenstein B, Schaffner W. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41:521-530, 1985.
34. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1989.
35. Gorman CM, Moffat LF, Howard BH. Recombinant genomes which express chloramphenicol acetyl transferase in mammalian cells. Mol Cell Biol 2:1044-1051, 1982.
36. Shapiro DJ, Sharp PA, Wahli WW, Keller MJ. A high-efficiency HeLa cell nuclear transcription extract. DNA 7:47-55, 1988.
37. Hennighausen L, Lubon H. Interaction of protein with DNA in vitro. Methods Enzymol 152:721-735, 1987.
38. Kadonaga JT, Carner KR, Masiarz FR, Tjian R. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 51:1079-1090, 1987.
39. Imagawa M, Chiu R, Karin M. Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP. Cell 51:251-260, 1987.
40. Chodosh LA, Baldwin AS, Carthew RW, Sharp PA. Human CCAAT-binding proteins have heterologous subunits. Cell 53:11-24, 1988.
41. Ryden TA, Beemon K. Avian retrovirus long terminal repeats bind CCAAT/enhancer-binding protein. Mol Cell Biol 9:1155-1164, 1989.
42. Courtois SJ, Lafontaine DA, Lemaigre FP, Durviaux SM, Rousseau GG. Nuclear factor-1 and activator protein-2 bind in a mutually exclusive way to overlapping promoter sequences and trans-activate the human growth hormone gene. Nucleic Acids Res 18:57-64, 1990.
43. Burns PA, Kemp CJ, Cannon JV, Lane DP, Bremner R, Balmain A. Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice. Oncogene 6:2363-2369, 1991.
44. Lee YH, Yano M, Liu SY, Matsunaga E, Johnson PF, González FJ. A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBPβ and an Sp1 factor. Mol Cell Biol 14:1383-1394, 1994.
45. Kozak M. Features in the 5′ non-coding sequences of rabbit α and β-globin mRNAs that affect translational efficiency. J Mol Biol 235:95-111, 1994.
46. Sagliocco FA, Vega-Laso MR, Zhu D, Tuite MF, McCarthy JEG, Brown AJP. The influence of 5′-secondary structures upon ribosome binding to mRNA during translation in yeast. J Biol Chem 268:26522-26530, 1993.
47. Gunther M, Frebourg T, Laithier M, et al. An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line. Mol Cell Biol 15:2490-2499, 1995.
48. Apt D, Chong T, Liu Y, Bernard HU. Nuclear factor I and epithelial cell-specific transcription of human papillomavirus type 16. J Virol 76:4455-4463, 1993.
49. Apt D, Liu Y, Bernard HU. Cloning and functional analysis of spliced isoforms of human nuclear factor I-X: Interference with transcriptional activation by NFI/CTF in a cell-type specific manner. Nucleic Acids Res 22:3825-3833, 1994.
50. Bernard HU, Apt D. Transcriptional control and cell type specificity of HPV gene expression. Arch Dermatol 130:210-215, 1994.
51. Hoppe-Seyler F, Butz K. Cellular control of human papillomavirus oncogene transcription. Mol Carcinog 10:134-141, 1994.