Immunoblotting patterns of cytoskeletal dendritic protein expression in human neocortex

Molecular and Chemical Neuropathology

Volumn 31, Issue 3, 1997, Pages 235-244

  Kaufmann, Walter E ^a,b   Taylor, Christopher V ^a   Lishaa, Nancy A ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

Cerebral cortex; Enhanced chemiluminescence; Human; Immunoblotting; MAP 5; Microtubule associated protein (MAP) 2; Neurofilaments; Sternberger monoclonals incorporated antibody 32 (SMI 32)

Indexed keywords

CYTOSKELETON PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 5; NEUROFILAMENT PROTEIN;

ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MONKEY; NEOCORTEX; NONHUMAN; OPTICAL DENSITY; PRIORITY JOURNAL; PROTEIN ANALYSIS;

EID: 0030777098     PISSN: 10447393     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02815127     Document Type: Article

References (30)

1. Abrams M. T., Reiss A. L., Freund L. S., Baumgardner T. L., Chase G. A., and Denckla M. B. (1994) Molecular-neurobehavioral associations in females with the fragile X full mutation. Am. J. Med. Genet. 51, 317-327.
2. Ang L. C., Munoz D. G., Shul D., and George D. H. (1991) SMI-32 immunoreactivity in human striate cortex during postnatal development. Dev. Brain Res. 61, 103-109.
3. Arnold S. E., Lee V. M.-Y., Gur R. E., and Trojanowski J. Q. (1991) Abnormal expression of two microtubule-associated proteins (MAP2 and MAPS) in specific subfields of the hippocampal formation in schizophrenia. Proc. Natl. Accid. Sci. USA 88, 10,850-10,854.
4. Dickson D. W., Ksiezak-Reding H., Liu W.-K., Davies P., Crowe A., and Yen S.-H. (1992) Immunocytochemistry of neurofibrillary tangles (NFT) with antibodies to subregions of tau protein: identification of hidden and cleaved tau epitopes in NFT. Acta Neuropathol. 84, 596-605.
5. Evers P. and Uylings H. B. M. (1994) Effects of microwave pretreatment on immunocytochemical staining of vibratome sections and tissue blocks of human cerebral cortex stored in formaldehyde fixative for long periods. J. Neurosci. Methods 55, 163-172.
6. Fischer I. and Shea T. B. (1991) Differential appearance of extensively phosphorylated forms of the high molecular weight neurofilament protein in regions of mouse brain during postnatal development. J. Neuroimmunol. 31, 73-81.
7. Hendry S. H. C. and Bhandari M. A. (1992) Neuronal organization and plasticity in adult monkey visual cortex: immunoreactivity for microtubule-associated protein 2. Vis. Neurosci. 9, 445-459.
8. Johnson G. V. M. and Jope R. S. (1992) The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration. J. Neurosci. Res. 33, 505-512.
9. Kalcheva N., Albala J. S., Binder L. I., and Shafit-Zagardo B. (1994) Localization of specific epitopes on human microtubule-associated protein 2. J. Neurochem. 6, 2336-2341.
10. Kaufmann W. E. (1996) Mental retardation and learning disorders: a neuropathological differentiation, in Developmental Disabilities in Infancy and Childhood, vol. 2 (Capute A. J. and Accardo P. J., eds.), pp. 49-70, Paul H/Brookes, Baltimore, MD.
11. Kaufmann W. E., Hohmann C. H., Israel J. J., and Naidu S. (1995b) Microtubule-associated protein 2 is abnormally expressed in the neocortex of Rett syndrome subjects and in a related animal model. Ann. Neurol. 38, 500.
12. Kaufmann W. E., Naidu S., and Budden S. (1995a) Abnormal expression of microtubule-associated protein 2 (MAP-2) in neocortex in Rett Syndrome. Neuropediatrics 26, 109-113.
13. Kaufmann W. E., Worley P. F., Pegg J., Bremer M., and Isakson P. (1996) COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc. Natl. Acad. Sci. USA 93, 2317-2321.
14. Knaus P., Betz H., and Rehm H. (1986) Expression of synaptophysin during postnatal development of the mouse brain. J. Neurochem. 47, 1302-1304.
15. Kunze D. and Rüstow B. (1993) Pathobiochemical aspects of cytoskeleton components. Eur. J. Clin. Chem. Clin. Biochem. 31, 477-489.
16. Leifer D. and Kowall N. W. (1993) Immunohistochemical patterns of selective cellular vulnerability. J. Neurol. Sci. 119, 217-228.
17. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
18. Luby-Phelps K., Taylor D. L., and Lanni F. (1986) Probing the structure of the cytoplasm. J. Cell Biol. 102, 2015-2022.
19. Mitchison T. and Kirschner M. (1988) Cytoskeletal dynamics and nerve growth. Neuron 1, 761-772.
20. Nassogne M.-C., Evrard P., and Courtoy P. J. (1995) Selective neuronal toxicity of cocaine in embryonic mouse brain cocultures. Proc. Natl. Acad. Sci. USA 92, 11,029-11,033.
21. Riederer B., Cohen R., and Matus A. (1986) MAP-5: a novel brain microtubule-associated protein under strong developmental regulation. J. Neurocytol. 15, 763-775.
22. Schilling G., Sharp A. H., Loev S. J., Wagster M. V., Li S.-H., Stine O. C., and Ross C. A. (1995) Expression of the Huntington's disease (IT 15) protein product in HD patients. Hum. Mol. Genet. 4, 1365-1371.
23. Sillevis Smitt P. A. E., van der Loos C., Vianney de Jong J. M. B., and Troost D. (1993) Tissue fixation methods alter the immunohistochemical demonstrability of neurofilament proteins, synaptophysin, and glial fibrillary acidic protein in human cerebellum. Acta Histochem. 95, 13-21.
24. Sims K. B., Crandall J. E., Kosik K. S., and Williams R. S. (1988) Microtubule-associated protein 2 (MAP 2) immunoreactivity in human fetal cortex. Brain Res. 449, 192-200.
25. Sternberger L. A. and Sternberger N. H. (1983) Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc. Natl. Acad. Sci. USA 83, 1536-1540.
26. Tan S. E., Abel E. L., and Berman R. F. (1993) Brain MAP-2 phosphorylation is decreased following prenatal alcohol exposure in rats. Alcohol 10, 391-396.
27. Ulloa L., Ledesma D., Montejo de Garcini E., and Diaz-Nido J. (1995) Axonal microtubule-associated proteins are phosphorylated in Alzheimer's disease in a similar way to that found in developing neurites. Biocell 19, 17-26.
28. Vermersch P., Delacourte A., Javoy-Agid F., Hauw J.-J., and Agid Y. (1993) Dementia in Parkinson's disease: biochemical evidence for cortical involvement using the immunodetection of abnormal Tau proteins. Ann. Neurol. 33, 445-450.
29. Woolf N. J. (1993) Cholinoceptive cells in rat cerebraf cortex: somatodendritic immunoreactivity for muscarinic receptor and cytoskeletal proteins. J. Chem. Neuroanat. 6, 375-390.
30. Woolf N. J., Young S. L., Johnson G. V. W., and Fanselow M. S. (1994) Pavlovian conditioning alters cortical microtubule-associated protein-2. NeuroReport 5, 1045-1048.