Site-specific mutagenesis of a recombinant anti-single-stranded DNA Fab. Role of heavy chain complementarity-determining region 3 residues in antigen interaction

Journal of Biological Chemistry

Volumn 272, Issue 43, 1997, Pages 26864-26870

  Komissarov, Andrey A ^a   Marchbank, Marie T ^a   Calcutt, Michael J ^a   Quinn, Thomas P ^a   Deutscher, Susan L ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; MUTANT PROTEIN; RECOMBINANT PROTEIN; SINGLE STRANDED DNA;

AMINO ACID SUBSTITUTION; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; BINDING SITE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANTIGEN-ANTIBODY COMPLEX; BINDING SITES, ANTIBODY; DNA, SINGLE-STRANDED; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

EID: 0030776843     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.43.26864     Document Type: Article

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