Serum testosterone levels after external beam radiation for clinically localized prostate cancer

International Journal of Radiation Oncology Biology Physics

Volumn 39, Issue 1, 1997, Pages 85-89

  Zagars, Gunar K ^a,b   Pollack, Alan ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Prostate cancer; Radiation; Testosterone

Indexed keywords

TESTOSTERONE;

ADULT; ARTICLE; CANCER LOCALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSTATE CANCER; RADIOIMMUNOASSAY; STATISTICAL ANALYSIS; STRESS; TESTOSTERONE BLOOD LEVEL; THERMOLUMINESCENCE DOSIMETER;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; HUMANS; MALE; MIDDLE AGED; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; TESTOSTERONE; TIME FACTORS;

EID: 0030776408     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00311-8     Document Type: Article

References (29)

1. Altman, D. G. Practical statistics for medical research. London: Chapman & Hall; 1991.
2. Amies, C. J.; Mameghan, H.; Rose, A.; Fisher, R. J. Testicular doses in definitive radiation therapy for localized prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 32:839-846; 1995.
3. Andriole, G. L.; Rao, G. S.; Kawakita, M.; Smith, D. S.; Ornstein, D. K. Reduced serum testosterone levels after radical retropubic prostatectomy (RRP) (Abstr.) J. Urol. 155:461A; 1996.
4. Cooper, C. S.; MacIndoe, J. H.; Perry, P. J.; Yates, W. R.; Williams, R. D. The effects of exogenous testosterone on total and free prostate specific antigen levels in healthy young men. J. Urol. 156:438-442; 1996.
5. Doering, C. H.; Kraemer, H. C.; Brodie, H. K.; Hamburg, D. A. A cycle of plasma testosterone in the human male. J. Clin. Endocrinol. Metab. 40:492-500; 1975.
6. Grigsby, P. W.; Perez, C. A. The effects of external beam radiotherapy on endocrine function in patients with carcinoma of the prostate. J. Urol. 135:726-727; 1986.
7. Gwicerman, A.; Maase, M.; Berthelsen. J. G.; Rorth, M.; Bertelsen, A.; Skakkebaek, N. E. Localised irradiation of testes with carcinoma in situ: Effects on Leydig cell function in 20 patients. J. Clin. Endocrinol. Metab. 73:596-603; 1991.
8. Isaacs, J. T. Role of androgens in prostatic cancer. Vitamins Horm. 49:433-502; 1994.
9. Lindh, A.; Carlstrom, K.; Eklund, J.; Wilking, N. Serum steroids and prolactin during and after major surgical trauma. Acta Anaesthesiol. Scand. 36:119-124; 1992.
10. Monath, J. R.; McCullough, D. L.; Hart, L. J.; Jarrow, J. P. Physiologic variations of serum testosterone within the normal range do not affect serum prostate-specific antigen. Urology 46:58-61; 1995.
11. Monda, J. M.; Myers, R. P.; Bostwick, D. G.; Oesterling, J. E. The correlation between serum prostate-specific antigen and prostate cancer is not influenced by the serum testosterone concentration. Urology 46:62-64; 1995.
12. Nader, S.; Schultz, P. N.; Cundiff, J. H.; Hussey, D. H.; Samaan, N. A. Endocrine profiles of patients treated with radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 9:1723-1726; 1983.
13. Perez, C. A. Presidential address of the 24th annual meeting of the American Society of Therapeutic Radiologists: Carcinoma of the prostate, a vexing biological and clinical enigma. Int. J. Radiat. Oncol. Biol. Phys. 9:1427-1438; 1983.
14. Pollack, A.; Zagars, G. K.; Starkschall, G.; Childress, C. H.; Kopplin, S.; Boyer, A. L.; Rosen, I. I. Conventional versus conformal radiotherapy for prostate cancer. Preliminary results of dosimetry and acute toxicity. Int. J. Radiat. Oncol. Biol. Phys. 34:555-564; 1996.
15. Rose, R. M.; Bourne, P.; Poe, R. O.; Mougey, E. H.; Collins, D. R.; Mason, J. W. Androgen responses to stress. Psychosom. Med. 31:418-436; 1969.
16. Schrader, S. M.; Turner, T. W.; Breitenstein, M. J.; Simon, S. D. Measuring male reproductive hormones for occupational field studies. J. Occup. Med. 35:574-576; 1993.
17. Seal, U. S. FSH and LH elevation after radiation for treatment of cancer of the prostate. Invest. Urol. 16:278-280; 1979.
18. Shalet, S. M. Effect of irradiation treatment on gonadal function in men treated for germ cell cancer. Eur. Urol. 23:148-152; 1993.
19. Shalet, S. M.; Tsatsoulis, A.; Whitehead, E.; Read, G. Vulnerability of the human Leydig cell to radiation damage is dependent on age. J. Endocrinol. 120:161-165; 1989.
20. Shapiro, E.; Kinsella, T. J.; Makuch, R. W.; Fraas, B. A.; Glatstein, E.; Rosenberg, S. A.; Sherrins, R. J. Effects of fractionated irradiation on endocrine aspects of testicular function. J. Clin. Oncol. 3:1232-1239; 1985.
21. Singer, F.; Zumoff, B. Subnormal serum testosterone levels in male internal medicine residents. Steroids 57:86-89; 1992.
22. Smals, A. G. H.; Kloppenborg, P. W. C.; Benraad, T. J. Circannual cycle in plasma testosterone levels in man. J. Clin. Endocrinol. Metab. 42:979-982; 1976.
23. Tomic, R.; Bergman, B.; Damber, J.-E.; Littbrand, B.; Lofroth, P. O. Effects of external radiation therapy for cancer of the prostate on the serum concentration of testosterone, follicle-stimulating hormone, luteinizing hormone and prolactin. J. Urol. 130:287-289; 1983.
24. Winters, S. J. Diurnal rhythm of testosterone and luteinizing hormone in hypogonadal men. J. Androl. 12:185-190; 1993.
25. Young, C. Y. F.; Andrews, P. E.; Montgomery, G. T.; Tindall, D. J. Tissue-specific and hormonal regulation of human prostate-specific glandular kallikrein. Biochemistry 31:818-824; 1992.
26. Zagars, G. K. Management of stage I seminoma: Radiotherapy. In: Horwich, A., ed. Testicular cancer, investigation and management. London: Chapman & Hall Medical; 1991:83-107.
27. Zagars, G. K.; Geara, F. B.; Pollack, A.; von Eschenbach, A. C. The T classification of clinically localized prostate cancer. An appraisal based on disease outcome following radiation therapy. Cancer 73:1904-1912; 1994.
28. Zagars, G. K.; Pollack, A.; von Eschenbach, A. C. Serum testosterone - A significant determinant of metastatic relapse for irradiated localized prostate cancer. Urology 49:327-334; 1997.
29. Zagars, G. K.; Sherman, N. E.; Babaian, R. J. Prostate-specific antigen and external beam radiotherapy in prostate cancer. Cancer 67:412-420; 1991.