An international evaluation of the cancer-preventive potential of nonsteroidal anti-inflammatory drugs

Cancer Epidemiology Biomarkers and Prevention

Volumn 6, Issue 9, 1997, Pages 749-753

  Vainio, Harri ^a   Morgan, Gareth ^a   Kleihues, Paul ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; SULINDAC;

ADENOMATOUS POLYP; ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER PREVENTION; CANCER RISK; CLINICAL TRIAL; COLORECTAL CANCER; CONFERENCE PAPER; GASTROINTESTINAL TOXICITY; HUMAN; LIVER TOXICITY; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICARCINOGENIC AGENTS; CHEMOPREVENTION; HUMANS; NEOPLASMS;

EID: 0030776215     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (21)

1. Stewart, B. W., McGregor, D., and Kleihues, P. Principles of Chemoprevention. IARC Sci. Pub. No. 139. Lyon, France: IARC, 1996.
2. Bennett, A., and Del Tacca, M. Proceedings: prostaglandins and human colonie carcinoma. Gut, 16: 409, 1975.
3. Pollard, M., and Luckert, P. H. Indomethacin treatment of rats with dimethylhydrazine-induced intestinal tumors. Cancer Treat. Rep., 64: 1323-1327, 1980.
4. Reddy, B. S., Tokumo, K., Kulkarni, N., Aligia, C, and Kellof, G. Inhibition of colon carcinogenesis by prostaglandin synthesis inhibitors and related compounds. Carcinogenesis (Lond.), 13: 1019-1023, 1992.
5. Kune, G. A., Kune, S., and Watson, L. F. Colorectal cancer risk, chronic illnesses, operations, and medications: case control results from the Melbourne Colorectal Cancer Study. Cancer Res., 48: 4399-4404, 1988.
6. Rosenberg, L., Palmer, J. R., Zauber, A. G., Warshauer, M. E., Stolley, P. D., and Shapiro, S. A hypothesis: non-steroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer. J. Natl. Cancer Inst., 83: 355-358, 1991.
7. Gann, P. H., Manson, J. E., Glynn, R. J., During, J. E., and Hennekens, C. H. Low dose aspirin and incidence of colorectal tumours in a randomized trial. J. Natl. Cancer Inst., 85: 1220-1224, 1993.
8. Greenberg, E. R., Baron, J. A., Freeman, T. H., Mandel, J. S., and Haile, R. Reduced risk of large bowel adenomas among aspirin users. J. Natl. Cancer Inst., 85: 912-916, 1993.
9. Suh, O., Mettlin, C., and Pettrelli, N. J. Aspirin use, cancer and polyps of the large bowel. Cancer (Phila.), 73: 1171-1177, 1993.
10. Thun, M. J., Namboodiri, M. N., and Heath, C. W. Aspirin use and reduced risk of fatal colon cancer. New Engl. J. Med., 325: 1593-1596, 1991.
11. Giovanucci, E., Egan, K. M., Hunter, D. J., Stampfer, M. J., Colditz, G. A., Willett, W. C., and Speizer, F. E. Aspirin and the reduced risk of Colorectal cancer in women. New Engl. J. Med., 333: 609-614, 1995.
12. Peleg, I. I., Lubin, M. F., Cotsonis, G. A., Clark, W. S., and Wilcox, C. M. Long-term use of nonsteroidal antiinflammatory drugs and other chemopreventors and risk of subsequent colorectal neoplasia. Dig. Dis. Sci., 41: 1319-1326, 1996.
13. Paganini-Hill, A., Hsu, G., Ross, R. K., and Henderson, B. E. Aspirin use and incidence of large-bowel cancer in a Califomian retirement community. J. Natl. Cancer Inst., 83: 1182-1183, 1991.
14. Waddell, W. R., and Loughry, R. W. Sulindac for polyposis of the colon. J. Surg. Oncol., 24: 83-87, 1983.
15. Waddell, W. R., Ganser, G. F., Cerise, E. J., and Loughry, R. W. Sulindac for polyposis of the colon. Am. J. Surg., 157: 175-178, 1989.
16. Labayle, D., Fischer, D., Vielh, P., Drouhin, F., Pariente, A., Bones, C., Duhamel, O., Trousset, M., and Attali, P. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology, 101: 635-639, 1991.
17. Rigau, J., Pique, J. M., Rubio, E., Planas, R., Tarrech, J. M., and Bordas, J. M. Effects of long term sulindac therapy on colonic polyposis. Ann. Intern. Med., 115: 952-954, 1991.
18. Giardiello, F. M., Hamilton, S. R., Krush, A. J., Paintadosi, S., Hylind, L. M., Celano, P., Booker, S. V., Robinson, C. R., and Offerhaus, G. J. A. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. New Engl. J. Med., 328: 1313-1316, 1993.
19. Niv, Y., and Fraser, G. M. Adenocarcinoma in the rectal segment in familial adenomatous polyposis is not prevented by sulindac therapy. Gastroenterology, 707: 854-857, 1994.
20. Lynch, H. T., Thorson, A. G., and Smyrk, T. Rectal cancer after prolonged sulindac chemoprevention. A case report. Cancer (Phila.), 75: 936-938, 1995.
21. Moser, A. R., Pitot, H. C., and Dove, W. F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science (Washington DC), 247: 322-324, 1990.