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Volumn 27, Issue 2-3, 1997, Pages 249-259

New antipsychotic medications: Strategies for evaluation and selected findings

Author keywords

Antipsychotic medications; Clinical trial designs; Clozapine; Olanzapine; Risperidone; Sertindole

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PLACEBO; RISPERIDONE; SERTINDOLE;

EID: 0030776066     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(97)00089-3     Document Type: Conference Paper
Times cited : (12)

References (45)
  • 1
    • 0027238608 scopus 로고
    • Clozapine-induced agranulocytosis: Incidence and risk factors in the United States
    • Alvir, J.M.J., Jeffrey, P.H., Lieberman, M.D., et al., 1993. Clozapine-induced agranulocytosis: incidence and risk factors in the United States. N. Engl. J. Med. 329, 162-167.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 162-167
    • Alvir, J.M.J.1    Jeffrey, P.H.2    Lieberman, M.D.3
  • 5
    • 0029949965 scopus 로고    scopus 로고
    • Treatment-resistant schizophrenia: Clinical experience with new antipsychotics
    • Bondolfi, G., Baumann, P., Dufour, H., 1996. Treatment-resistant schizophrenia: clinical experience with new antipsychotics. Eur. Neuropsychopharmacol. 6, 21-25.
    • (1996) Eur. Neuropsychopharmacol. , vol.6 , pp. 21-25
    • Bondolfi, G.1    Baumann, P.2    Dufour, H.3
  • 7
    • 0027972344 scopus 로고
    • Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia
    • Breier, A., Buchanan, R.W., Kirkpatrick, B., et al., 1994. Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia. Am. J. Psychiatry 151, 20-26.
    • (1994) Am. J. Psychiatry , vol.151 , pp. 20-26
    • Breier, A.1    Buchanan, R.W.2    Kirkpatrick, B.3
  • 8
    • 1842301779 scopus 로고    scopus 로고
    • The rationale and ethics of medication-free research in schizophrenia
    • Carpenter, W.T., , Schooler, N.R., Kane, J.M., 1997. The rationale and ethics of medication-free research in schizophrenia. Arch. Gen. Psychiatry 54, 401-407.
    • (1997) Arch. Gen. Psychiatry , vol.54 , pp. 401-407
    • Carpenter, W.T.1    Schooler, N.R.2    Kane, J.M.3
  • 10
    • 0027475985 scopus 로고
    • A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenia patients
    • Chouinard, G., Jones, B., Remington, G., et al., 1993. A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenia patients. J. Clin. Psychopharmacol. 13, 25-29.
    • (1993) J. Clin. Psychopharmacol. , vol.13 , pp. 25-29
    • Chouinard, G.1    Jones, B.2    Remington, G.3
  • 11
    • 0030532233 scopus 로고    scopus 로고
    • Risperidone: A new, novel (and better?) antipsychotic
    • Davis, J.M., Janicak, P.G., 1996. Risperidone: a new, novel (and better?) antipsychotic. Psychiatric Ann. 26, 78-87.
    • (1996) Psychiatric Ann. , vol.26 , pp. 78-87
    • Davis, J.M.1    Janicak, P.G.2
  • 12
    • 0343698504 scopus 로고
    • Risperidone in the treatment of first-episode psychotic patients: A double-blind multicenter study
    • Miami, Florida, 20-25 May 1995. New Research Program and Abstracts, NR465
    • Emsley, R.A., McCreadie, R., Lemmens, P., 1995. Risperidone in the treatment of first-episode psychotic patients: a double-blind multicenter study. American Psychiatric Association 148th Annual Meeting, Miami, Florida, 20-25 May 1995. New Research Program and Abstracts, NR465.
    • (1995) American Psychiatric Association 148th Annual Meeting
    • Emsley, R.A.1    McCreadie, R.2    Lemmens, P.3
  • 15
  • 16
    • 0018686085 scopus 로고
    • Depot fluphenazine and social therapy in the aftercare of schizophrenic patients: Relapse analyses of a two-year controlled trial
    • Hogarty, G.E., Schooler, N.R., Ulrich, R., et al., 1979. Depot fluphenazine and social therapy in the aftercare of schizophrenic patients: relapse analyses of a two-year controlled trial. Arch. Gen. Psychiatry 36, 1283-1294..
    • (1979) Arch. Gen. Psychiatry , vol.36 , pp. 1283-1294
    • Hogarty, G.E.1    Schooler, N.R.2    Ulrich, R.3
  • 19
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic
    • Kane, J., Honingfeld, G., Singer, J., et al., 1988. Clozapine for the treatment-resistant schizophrenic. Arch. Gen. Psychiatry 45, 789-796.
    • (1988) Arch. Gen. Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honingfeld, G.2    Singer, J.3
  • 20
    • 0002945274 scopus 로고    scopus 로고
    • The use of placebo controls in psychiatric research
    • Shamoo, A.E. (Ed.), Gordon and Breach Science, The Netherlands
    • Kane J., Borenstein M., 1997. The use of placebo controls in psychiatric research. In: Shamoo, A.E. (Ed.), Ethics in Neurobiological Research with Human Subjects. Gordon and Breach Science, The Netherlands, pp. 207-214.
    • (1997) Ethics in Neurobiological Research with Human Subjects , pp. 207-214
    • Kane, J.1    Borenstein, M.2
  • 22
    • 0342828015 scopus 로고
    • The comparative effectiveness of six phenothiazine compounds, phenobarbitol and inert placebo in the treatment of acutely ill patients: Global measures of severity of illness
    • Kurland, A.A., Hanlon, T.E., Taton, M.H., et al., 1961. The comparative effectiveness of six phenothiazine compounds, phenobarbitol and inert placebo in the treatment of acutely ill patients: global measures of severity of illness. J. Nerv. Ment. Dis. 133, 1-18..
    • (1961) J. Nerv. Ment. Dis. , vol.133 , pp. 1-18
    • Kurland, A.A.1    Hanlon, T.E.2    Taton, M.H.3
  • 23
    • 0342828016 scopus 로고
    • Drug treatment of schizophrenic patients: A comparative evaluation f chlorpromazine, chlorprothixine, fluphenazine, reserpine, thioridazine and trifluopromazine
    • Lasky, J.J., Klett, C.J., Caffey, E.M., et al., 1962. Drug treatment of schizophrenic patients: a comparative evaluation f chlorpromazine, chlorprothixine, fluphenazine, reserpine, thioridazine and trifluopromazine. Dis. Nervous System 23, 698-706..
    • (1962) Dis. Nervous System , vol.23 , pp. 698-706
    • Lasky, J.J.1    Klett, C.J.2    Caffey, E.M.3
  • 24
    • 84970838697 scopus 로고
    • Trial of maintenance therapy in schizophrenia
    • Leff, J.P., Wing, J.K., 1971. Trial of maintenance therapy in schizophrenia. Br. Med. J. 3, 559-604..
    • (1971) Br. Med. J. , vol.3 , pp. 559-604
    • Leff, J.P.1    Wing, J.K.2
  • 25
    • 0028237637 scopus 로고
    • Risperidone: A novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity
    • Leysen, J.E., Janssen, P.M.F., Megens, A.A.H.P., Schotte, A., 1994. Risperidone: A novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J. Clin. Psychiatry 55, 5-12.
    • (1994) J. Clin. Psychiatry , vol.55 , pp. 5-12
    • Leysen, J.E.1    Janssen, P.M.F.2    Megens, A.A.H.P.3    Schotte, A.4
  • 26
    • 0028799828 scopus 로고
    • Efficacy of risperidone treatment for psychoses associated with schizophrenia, schizoaffective disorder, bipolar disorder, or senile dementia in 11 geriatric patients: A case series
    • Madhusoodanan, S., Brenner, R., Araujo, L., Abaza, A., 1995. Efficacy of risperidone treatment for psychoses associated with schizophrenia, schizoaffective disorder, bipolar disorder, or senile dementia in 11 geriatric patients: a case series. J. Clin. Psychiatry 56, 514-518..
    • (1995) J. Clin. Psychiatry , vol.56 , pp. 514-518
    • Madhusoodanan, S.1    Brenner, R.2    Araujo, L.3    Abaza, A.4
  • 27
    • 0023184229 scopus 로고
    • Low and conventional dose maintenance therapy with fluphenazine deconate: Two year outcome
    • Marder, S.R., Van Putten, T., , Mintz, J., et al., 1987. Low and conventional dose maintenance therapy with fluphenazine deconate: Two year outcome. Arch. Gen. Psychiatry 44, 518-521.
    • (1987) Arch. Gen. Psychiatry , vol.44 , pp. 518-521
    • Marder, S.R.1    Van Putten, T.2    Mintz, J.3
  • 28
    • 0028342655 scopus 로고
    • Risperidone in the treat-ment of schizophrenia
    • Marder, S.R., Meibach, R.C., 1994. Risperidone in the treat-ment of schizophrenia. Am. J. Psychiatry 151, 825-835..
    • (1994) Am. J. Psychiatry , vol.151 , pp. 825-835
    • Marder, S.R.1    Meibach, R.C.2
  • 29
    • 0024989576 scopus 로고
    • Effects of six months of clozapine treatment on the quality of life of chronic schizophrenic patients
    • Meltzer, H.Y., Burnett, S., Bastani, B., Ramirez, L., 1990. Effects of six months of clozapine treatment on the quality of life of chronic schizophrenic patients. Hosp. Community Psychiatry 41, 892-897.
    • (1990) Hosp. Community Psychiatry , vol.41 , pp. 892-897
    • Meltzer, H.Y.1    Burnett, S.2    Bastani, B.3    Ramirez, L.4
  • 30
    • 84941824613 scopus 로고
    • Phenothiazine treatment in acute schizophrenia
    • National Institute of Mental Health-Psychopharmacology Service Center Collaborative Study Group (NIMH-PSCN), 1962. Phenothiazine treatment in acute schizophrenia. Arch. Gen. Psychiatry 10, 246-261.
    • (1962) Arch. Gen. Psychiatry , vol.10 , pp. 246-261
  • 31
    • 0014098537 scopus 로고
    • Differences in clinical effects of three phenothiazines in 'acute' schizophrenia
    • National Institute of Mental Health Psychopharmacology Research Branch Collaborative Study Group (NIMHPRBCSG), 1967. Differences in clinical effects of three phenothiazines in 'acute' schizophrenia. Dis. Nerv. Sys. 28, 369-383.
    • (1967) Dis. Nerv. Sys. , vol.28 , pp. 369-383
  • 32
    • 0342393238 scopus 로고    scopus 로고
    • Restabilization after relapse in the Treatment Strategies in Schizophrenia (TSS) Study
    • in press
    • Pandalai, S.P., Schooler, N.R., Manevitz, A. et al., in press. Restabilization after relapse in the Treatment Strategies in Schizophrenia (TSS) Study. Psychopharm. Bull.
    • Psychopharm. Bull.
    • Pandalai, S.P.1    Schooler, N.R.2    Manevitz, A.3
  • 33
    • 0018132565 scopus 로고
    • Clinical trial methodology
    • Peto, R., 1978. . Clinical trial methodology. Biomedicine 28, 24-36.
    • (1978) Biomedicine , vol.28 , pp. 24-36
    • Peto, R.1
  • 34
    • 0028865612 scopus 로고
    • Risperidone in the treatment of chronic schizophrenic patients: A multinational multi-center double-blind parallel-group study versus haloperidol
    • Peuskens, J., Risperidone Study Group, 1995. Risperidone in the treatment of chronic schizophrenic patients: a multinational multi-center double-blind parallel-group study versus haloperidol. Br. J. Psychiatry 166, 712-726.
    • (1995) Br. J. Psychiatry , vol.166 , pp. 712-726
    • Peuskens, J.1
  • 35
    • 0029916196 scopus 로고    scopus 로고
    • Subject selection biases in clinical trials: Data from a multicenter schizophrenia treatment study
    • Robinson, D., Woerner, M.G., Pollack, S., Lerner, G., 1996. Subject selection biases in clinical trials: data from a multicenter schizophrenia treatment study. J. Clin. Psychopharmacol. 16, 170-176.
    • (1996) J. Clin. Psychopharmacol. , vol.16 , pp. 170-176
    • Robinson, D.1    Woerner, M.G.2    Pollack, S.3    Lerner, G.4
  • 36
    • 0025988340 scopus 로고
    • Prospective study of tardive dyskinesia incidence in the elderly
    • Saltz, B.L., Woerner, M.G., , Kane, J.M., et al., 1991. Prospective study of tardive dyskinesia incidence in the elderly. JAMA 266, 2402-2406..
    • (1991) JAMA , vol.266 , pp. 2402-2406
    • Saltz, B.L.1    Woerner, M.G.2    Kane, J.M.3
  • 37
    • 0028836837 scopus 로고
    • Clozapine in older patients with psychosis and behavioral disruption
    • Salzman, C., Vaccaro, B., , Lieff, J., et al., 1995. Clozapine in older patients with psychosis and behavioral disruption. Am. J. Geriatr. Psychiatry 3, 26-33.
    • (1995) Am. J. Geriatr. Psychiatry , vol.3 , pp. 26-33
    • Salzman, C.1    Vaccaro, B.2    Lieff, J.3
  • 38
    • 0026042050 scopus 로고
    • Maintenance medication for schizophrenia: Strategies for dose reduction
    • Schooler, N.R., 1991. Maintenance medication for schizophrenia: strategies for dose reduction. Schizophr. Bull. 17, 311-323..
    • (1991) Schizophr. Bull. , vol.17 , pp. 311-323
    • Schooler, N.R.1
  • 39
    • 0038329968 scopus 로고
    • Efficacy of clozapine vs haloperidol in a long term clinical trial: Preliminary findings
    • Schooler, N.R., Kane, J., Marder, S., et al., 1995, Efficacy of clozapine vs haloperidol in a long term clinical trial: Preliminary findings. Schizophr. Res. 15, 165
    • (1995) Schizophr. Res. , vol.15 , pp. 165
    • Schooler, N.R.1    Kane, J.2    Marder, S.3
  • 40
    • 0030914609 scopus 로고    scopus 로고
    • Relapse and rehospitalization during maintenance treatment of schizophrenia: The effects of dose reduction and family treatment
    • Schooler, N.R., Keith, S.J., Severe, J.B., et al., 1997. Relapse and rehospitalization during maintenance treatment of schizophrenia: the effects of dose reduction and family treatment. Arch. Gen. Psychiatry 54, 453-464.
    • (1997) Arch. Gen. Psychiatry , vol.54 , pp. 453-464
    • Schooler, N.R.1    Keith, S.J.2    Severe, J.B.3
  • 41
    • 0342393237 scopus 로고    scopus 로고
    • Providing quality care in the context of clinical research
    • in press. Pincus, H. (Ed.), American Psychiatric Press
    • Schooler, N.R., Baker, R.W., in press. Providing quality care in the context of clinical research. In: Pincus, H. (Ed.), Informed Consent: A Resource Manual for Investigators, American Psychiatric Press.
    • Informed Consent: A Resource Manual for Investigators
    • Schooler, N.R.1    Baker, R.W.2
  • 42
    • 0029811287 scopus 로고    scopus 로고
    • Efficacy of risperidone in reducing positive and negative symptoms in medication-refractory schizophrenia: An open prospective study
    • Smith, R.C., Chua, J.W., Lipetsker, B., Bhattacharyya, A., 1996. Efficacy of risperidone in reducing positive and negative symptoms in medication-refractory schizophrenia: an open prospective study. J. Clin. Psychiatry 54, 460-466.
    • (1996) J. Clin. Psychiatry , vol.54 , pp. 460-466
    • Smith, R.C.1    Chua, J.W.2    Lipetsker, B.3    Bhattacharyya, A.4
  • 43
    • 0018861758 scopus 로고
    • Informed consent and bias in samples of schizophrenic subjects at risk for drug withdrawal
    • Spohn, H.E., Fitzpatrick, T., 1980. . Informed consent and bias in samples of schizophrenic subjects at risk for drug withdrawal. J. Abnorm. Psychol. 89, 79-92.
    • (1980) J. Abnorm. Psychol. , vol.89 , pp. 79-92
    • Spohn, H.E.1    Fitzpatrick, T.2
  • 44
    • 0029916389 scopus 로고    scopus 로고
    • A randomized, controlled dose-ranging trial of sertindole in patient with schizophrenia
    • van Kammen, D.P., McEvoy, J.P., Targum S.D. et al., 1996. A randomized, controlled dose-ranging trial of sertindole in patient with schizophrenia. Psychopharmacology 124, 168-175.
    • (1996) Psychopharmacology , vol.124 , pp. 168-175
    • Van Kammen, D.P.1    McEvoy, J.P.2    Targum, S.D.3
  • 45
    • 0030913838 scopus 로고    scopus 로고
    • Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia
    • Zimbroff, D.L., Kane, J.M., Tamminga, C.A., et al., 1997. Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Am. J. Psychiatry 154, 782-791..
    • (1997) Am. J. Psychiatry , vol.154 , pp. 782-791
    • Zimbroff, D.L.1    Kane, J.M.2    Tamminga, C.A.3


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