-
1
-
-
0026743925
-
Studies on zwitter-ionization of drugs. I: Synthesis and pharmacological activities of N-alkylcarboxylic acid derivatives of 4-(2-chlorodibenz[b,f][1,4]oxazepin-11-yl)-piperazine, 4-(2-chlorodibenzo[b,f][1,4]thiazepin-11-yl)piperazine, and 4-(11H-dibenz[b,e]azepin-6-yl)piperazine
-
Abstr in English
-
Muramatsu H, Sawanishi H, Iwasaki N, Kakiuchi M, Ohashi T, Kato H and Ito Y: Studies on zwitter-ionization of drugs. I: Synthesis and pharmacological activities of N-alkylcarboxylic acid derivatives of 4-(2-chlorodibenz[b,f][1,4]oxazepin-11-yl)-piperazine, 4-(2-chlorodibenzo[b,f][1,4]thiazepin-11-yl)piperazine, and 4-(11H-dibenz[b,e]azepin-6-yl)piperazine. Yakugaku Zasshi 112, 479-488 (1992) (Abstr in English)
-
(1992)
Yakugaku Zasshi
, vol.112
, pp. 479-488
-
-
Muramatsu, H.1
Sawanishi, H.2
Iwasaki, N.3
Kakiuchi, M.4
Ohashi, T.5
Kato, H.6
Ito, Y.7
-
2
-
-
0027763538
-
Study on zwitter-ionization of drugs. II: Synthesis and pharmacological activity of some N-[3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl]-N-metylamino- and N-[3-(6H-dibenz[b,e]oxepin-11-ylidene)propyl]-N-methylamino-alkanoic acid derivatives and related compounds
-
Tokyo
-
Muramatsu H, Sawanishi H, Iwasaki N, Kakiuchi M, Ohashi T, Kato H and Ito Y: Study on zwitter-ionization of drugs. II: Synthesis and pharmacological activity of some N-[3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl]-N-metylamino-and N-[3-(6H-dibenz[b,e]oxepin-11-ylidene)propyl]-N-methylamino-alkanoic acid derivatives and related compounds. Chem Pharm Bull (Tokyo) 41, 1987-1993 (1993)
-
(1993)
Chem Pharm Bull
, vol.41
, pp. 1987-1993
-
-
Muramatsu, H.1
Sawanishi, H.2
Iwasaki, N.3
Kakiuchi, M.4
Ohashi, T.5
Kato, H.6
Ito, Y.7
-
3
-
-
0028212724
-
Studies on zwitter-ionization of drugs. III: Synthesis and pharmacological activities of N-alkylcarboxylic acid derivatives of 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino-[1,2-a]azepine and 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7] cyclohepta[1,2-c]pyridine
-
Abstr in English
-
Muramatsu H, Sawanishi H, Iwasaki N, Kakiuchi M, Ohashi T, Kato H and Ito Y: Studies on zwitter-ionization of drugs. III: Synthesis and pharmacological activities of N-alkylcarboxylic acid derivatives of 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino-[1,2-a]azepine and 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7] cyclohepta[1,2-c]pyridine. Yakugaku Zasshi 114, 54-62 (1994) (Abstr in English)
-
(1994)
Yakugaku Zasshi
, vol.114
, pp. 54-62
-
-
Muramatsu, H.1
Sawanishi, H.2
Iwasaki, N.3
Kakiuchi, M.4
Ohashi, T.5
Kato, H.6
Ito, Y.7
-
4
-
-
0028027848
-
Amphoteric drugs. I: Synthesis and antiallergic activity of [4-(diphenylmethoxy)piperidino]-, [4-(diphenylmethyl)piperazinyl]-and [4-(diphenylmethylene)piperidino]alkanoic acid derivatives
-
Tokyo
-
Iwasaki N, Sakaguchi J, Ohashi T, Takahara E, Ogawa N, Yasuda S, Koshinaka E, Kato H, Ito Y and Sawanishi H: Amphoteric drugs. I: Synthesis and antiallergic activity of [4-(diphenylmethoxy)piperidino]-, [4-(diphenylmethyl)piperazinyl]-and [4-(diphenylmethylene)piperidino]alkanoic acid derivatives. Chem Pharm Bull (Tokyo) 42, 2276-2284 (1994)
-
(1994)
Chem Pharm Bull
, vol.42
, pp. 2276-2284
-
-
Iwasaki, N.1
Sakaguchi, J.2
Ohashi, T.3
Takahara, E.4
Ogawa, N.5
Yasuda, S.6
Koshinaka, E.7
Kato, H.8
Ito, Y.9
Sawanishi, H.10
-
5
-
-
0028061764
-
Amphoteric drugs. II: Synthesis and antiallergic activity of [4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidino]alkanoic acid derivatives and related compounds
-
Tokyo
-
Iwasaki N, Sakaguchi J, Ohashi T, Yamazaki M, Ogawa N, Yasuda S, Koshinaka E, Kato H, Ito Y and Sawanishi H: Amphoteric drugs. II: Synthesis and antiallergic activity of [4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidino]alkanoic acid derivatives and related compounds. Chem Pharm Bull (Tokyo) 42, 2285-2290 (1994)
-
(1994)
Chem Pharm Bull
, vol.42
, pp. 2285-2290
-
-
Iwasaki, N.1
Sakaguchi, J.2
Ohashi, T.3
Yamazaki, M.4
Ogawa, N.5
Yasuda, S.6
Koshinaka, E.7
Kato, H.8
Ito, Y.9
Sawanishi, H.10
-
6
-
-
0029025273
-
Amphoteric drugs. 3: Synthesis and antiallergic activity of 3-[(5,11-dihydro[1]-benzoxepino[4,3-b]-piperidin-11-ylidene)piperidino]propionic acid derivatives and related compounds
-
Iwasaki N, Ohashi T, Musoh K, Nishino H, Kado N, Yasuda S, Kato H and Ito Y: Amphoteric drugs. 3: Synthesis and antiallergic activity of 3-[(5,11-dihydro[1]-benzoxepino[4,3-b]-piperidin-11-ylidene)piperidino]propionic acid derivatives and related compounds. J Med Chem 38, 496-507 (1995)
-
(1995)
J Med Chem
, vol.38
, pp. 496-507
-
-
Iwasaki, N.1
Ohashi, T.2
Musoh, K.3
Nishino, H.4
Kado, N.5
Yasuda, S.6
Kato, H.7
Ito, Y.8
-
7
-
-
0006856654
-
Pharmacological studies of HSR-609, a novel amphoteric antiallergic agent (1): Effects on various allergic models
-
Musoh K, Ohashi T, Takahashi H, Iwanaga Y, Morikawa K, Kato H and Ito Y: Pharmacological studies of HSR-609, a novel amphoteric antiallergic agent (1): Effects on various allergic models. Jpn J Pharmacol 67, Suppl I, 285P (1995)
-
(1995)
Jpn J Pharmacol
, vol.67
, Issue.1 SUPPL.
-
-
Musoh, K.1
Ohashi, T.2
Takahashi, H.3
Iwanaga, Y.4
Morikawa, K.5
Kato, H.6
Ito, Y.7
-
8
-
-
0006847849
-
Pharmacological studies of HSR-609, a novel amphoteric antiallergic agent (2): Organ specificity of antihistamine action
-
Kawamura K, Hosotani T, Ohashi T, Kimura T, Watanabe Y, Iwanaga Y, Morikawa K, Kato H, Ito Y and Gomi Y: Pharmacological studies of HSR-609, a novel amphoteric antiallergic agent (2): Organ specificity of antihistamine action. Jpn J Pharmacol 67, Suppl I, 285P (1995)
-
(1995)
Jpn J Pharmacol
, vol.67
, Issue.1 SUPPL.
-
-
Kawamura, K.1
Hosotani, T.2
Ohashi, T.3
Kimura, T.4
Watanabe, Y.5
Iwanaga, Y.6
Morikawa, K.7
Kato, H.8
Ito, Y.9
Gomi, Y.10
-
11
-
-
85004774532
-
Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivities
-
Juniper EF, Cartier A, Trebilcock AL, Frith PA, Dolovich J and Hargreave FE: Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivities. Clin Allergy 11, 61-66 (1981)
-
(1981)
Clin Allergy
, vol.11
, pp. 61-66
-
-
Juniper, E.F.1
Cartier, A.2
Trebilcock, A.L.3
Frith, P.A.4
Dolovich, J.5
Hargreave, F.E.6
-
12
-
-
0024404353
-
Azelastine: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential
-
McTavish D and Sorkin EM: Azelastine: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential. Drugs 38, 778-800 (1989)
-
(1989)
Drugs
, vol.38
, pp. 778-800
-
-
McTavish, D.1
Sorkin, E.M.2
-
13
-
-
0028173646
-
1-receptor antagonists: Comparative tolerability and safety
-
1-receptor antagonists: Comparative tolerability and safety. Drug Safety 10, 350-380 (1994)
-
(1994)
Drug Safety
, vol.10
, pp. 350-380
-
-
Estelle, F.1
Simons, R.2
-
14
-
-
0003092787
-
Histamine, bradykinin, and their antagonists
-
Edited by Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Gilman AG, McGraw-Hill, New York
-
Babe KS and Serafin WE: Histamine, bradykinin, and their antagonists. In The Pharmacological Basis of Therapeutics, 9th ed, Edited by Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Gilman AG, pp 581-600, McGraw-Hill, New York (1996)
-
(1996)
The Pharmacological Basis of Therapeutics, 9th Ed
, pp. 581-600
-
-
Babe, K.S.1
Serafin, W.E.2
-
15
-
-
0014424692
-
Comprehensive observational assessment: Ia. A sysquantitative procedure for assessing the behavioral and physiologic state of the mouse
-
Berlin
-
Irwin S: Comprehensive observational assessment: Ia. A sysquantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia (Berlin) 13, 222-257 (1968)
-
(1968)
Psychopharmacologia
, vol.13
, pp. 222-257
-
-
Irwin, S.1
-
17
-
-
0021248301
-
Pharmacology of a new sleep inducer, 1H-1,2,4-triazolyl benzophenone derivative, 450191-S (II): Sleep-inducing activity and effect on the motor system
-
Abstr in English
-
Yamamoto K, Matsushita A, Sawada T, Naito Y, Yoshimura K, Takesue H, Utsumi S, Kawasaki K, Hirono S, Koshida H and Tazaki T: Pharmacology of a new sleep inducer, 1H-1,2,4-triazolyl benzophenone derivative, 450191-S (II): Sleep-inducing activity and effect on the motor system. Folia Pharmacol Jpn 84, 25-89 (1984) (Abstr in English)
-
(1984)
Folia Pharmacol Jpn
, vol.84
, pp. 25-89
-
-
Yamamoto, K.1
Matsushita, A.2
Sawada, T.3
Naito, Y.4
Yoshimura, K.5
Takesue, H.6
Utsumi, S.7
Kawasaki, K.8
Hirono, S.9
Koshida, H.10
Tazaki, T.11
-
18
-
-
10644244600
-
The rabbit diencephalon in stereotaxic coordinates
-
Sawyer CH, Everett JW and Green JD: The rabbit diencephalon in stereotaxic coordinates. J Comp Neurol 101, 801-824 (1954)
-
(1954)
J Comp Neurol
, vol.101
, pp. 801-824
-
-
Sawyer, C.H.1
Everett, J.W.2
Green, J.D.3
-
19
-
-
0025924519
-
Effects of antihistaminics on locomotor activity in mice: Comparison with opiate and amphetamine-induced hyperactivity
-
Leza JC, Lizasoain I and Lorenzo P: Effects of antihistaminics on locomotor activity in mice: Comparison with opiate and amphetamine-induced hyperactivity. Gen Pharmacol 22, 293-296 (1991)
-
(1991)
Gen Pharmacol
, vol.22
, pp. 293-296
-
-
Leza, J.C.1
Lizasoain, I.2
Lorenzo, P.3
-
20
-
-
0024404414
-
Effect of epinastine, a new antiallergic agent, on the central nervous system
-
Tasaka K, Kamei C, Nakano S, Tsujimoto S and Chung YH: Effect of epinastine, a new antiallergic agent, on the central nervous system. Pharmacometrics 38, 53-62 (1989)
-
(1989)
Pharmacometrics
, vol.38
, pp. 53-62
-
-
Tasaka, K.1
Kamei, C.2
Nakano, S.3
Tsujimoto, S.4
Chung, Y.H.5
-
21
-
-
0023096152
-
Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assay
-
Kubo N, Shirakawa O, Kuno T and Tanaka C: Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assay. Jpn J Pharmacol 43, 277-282 (1987)
-
(1987)
Jpn J Pharmacol
, vol.43
, pp. 277-282
-
-
Kubo, N.1
Shirakawa, O.2
Kuno, T.3
Tanaka, C.4
-
22
-
-
0023745712
-
General pharmacology of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate: 1st Communication: Effects on the central nervous system
-
Saito T, Fukuda T, Sukamoto T, Yoshidomi M, Morimoto Y, Shimohara K and Ito K: General pharmacology of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate: 1st Communication: Effects on the central nervous system. Arzneimittelforschung 38, 66-69 (1988)
-
(1988)
Arzneimittelforschung
, vol.38
, pp. 66-69
-
-
Saito, T.1
Fukuda, T.2
Sukamoto, T.3
Yoshidomi, M.4
Morimoto, Y.5
Shimohara, K.6
Ito, K.7
-
23
-
-
0014458913
-
Activity of antihistamines in laboratory antidepressant tests
-
Barnett A, Taber RI and Roth FE: Activity of antihistamines in laboratory antidepressant tests. Int J Neuropharmacol 8, 73-79 (1969)
-
(1969)
Int J Neuropharmacol
, vol.8
, pp. 73-79
-
-
Barnett, A.1
Taber, R.I.2
Roth, F.E.3
-
24
-
-
0022514494
-
Studies on the barbital-type physical dependence liability of terfenadine in mice and rats
-
Abstr in English
-
Kaneto H, Kaneda H, Taira K, Deguchi Y and Hanada S: Studies on the barbital-type physical dependence liability of terfenadine in mice and rats. Pharmacometrics 31, 579-586 (1986) (Abstr in English)
-
(1986)
Pharmacometrics
, vol.31
, pp. 579-586
-
-
Kaneto, H.1
Kaneda, H.2
Taira, K.3
Deguchi, Y.4
Hanada, S.5
-
25
-
-
0026671408
-
Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin
-
Honig PK, Woosley RL, Zamani K, Conner DP and Cantilena LR: Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin. Clin Pharmacol Ther 52, 231-238 (1992)
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 231-238
-
-
Honig, P.K.1
Woosley, R.L.2
Zamani, K.3
Conner, D.P.4
Cantilena, L.R.5
-
26
-
-
0000965479
-
Hypnotics and sedatives; Ethanol
-
Edited by Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Gilman AG, McGraw-Hill, New York
-
Hobbs WR, Rall TW and Verdoorn TA: Hypnotics and sedatives; Ethanol. In The Pharmacological Basis of Therapeutics, 9th ed, Edited by Hardman JG, Limbird LE, Molinoff PB, Ruddon RW and Gilman AG, pp 361-396, McGraw-Hill, New York (1996)
-
(1996)
The Pharmacological Basis of Therapeutics, 9th Ed
, pp. 361-396
-
-
Hobbs, W.R.1
Rall, T.W.2
Verdoorn, T.A.3
-
27
-
-
0023760095
-
In vitro and in vivo studies of the non-sedating antihistamine epinastine
-
Fügner A, Bechtel WD, Kuhn FJ and Mierau J: In vitro and in vivo studies of the non-sedating antihistamine epinastine. Arzneimittelforschung 38, 1446-1453 (1988)
-
(1988)
Arzneimittelforschung
, vol.38
, pp. 1446-1453
-
-
Fügner, A.1
Bechtel, W.D.2
Kuhn, F.J.3
Mierau, J.4
-
28
-
-
0023269535
-
Comparative effects of loratadine and selected antihistamines on sleep-waking patterns in the cat
-
Ongini E, Marzanatti M and Guzzon V: Comparative effects of loratadine and selected antihistamines on sleep-waking patterns in the cat. Drug Dev Res 10, 75-83 (1987)
-
(1987)
Drug Dev Res
, vol.10
, pp. 75-83
-
-
Ongini, E.1
Marzanatti, M.2
Guzzon, V.3
-
29
-
-
0014125460
-
Cholinergic agonist-antagonist interactions on neocortical and limbic EEG activation
-
Yamamoto K and Domino EF: Cholinergic agonist-antagonist interactions on neocortical and limbic EEG activation. Int J Neuropharmacol 6, 357-373 (1967)
-
(1967)
Int J Neuropharmacol
, vol.6
, pp. 357-373
-
-
Yamamoto, K.1
Domino, E.F.2
-
30
-
-
1842315114
-
Sleep factors; Models concerning their multiple interactions and specificity for sleep
-
Edited by Inoué S and Krueger JM, SPB Academic Publishing, Hague
-
Krueger JM, Obal F, Toth L, Johannsen L, Cady AB and Opp M: Sleep factors; Models concerning their multiple interactions and specificity for sleep. In Endogenous Sleep Factors, Edited by Inoué S and Krueger JM, pp 19-29, SPB Academic Publishing, Hague (1990)
-
(1990)
Endogenous Sleep Factors
, pp. 19-29
-
-
Krueger, J.M.1
Obal, F.2
Toth, L.3
Johannsen, L.4
Cady, A.B.5
Opp, M.6
-
31
-
-
0015276837
-
The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle
-
Jouvet M: The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle. Ergeb Physiol 64, 166-307 (1972)
-
(1972)
Ergeb Physiol
, vol.64
, pp. 166-307
-
-
Jouvet, M.1
-
32
-
-
0002253731
-
Cholinergic mechanisms and sleep
-
Edited by Waser PG, Raven Press, New York
-
Jouvet M: Cholinergic mechanisms and sleep. In Cholinergic Mechanisms, Edited by Waser PG, pp 455-476, Raven Press, New York (1975)
-
(1975)
Cholinergic Mechanisms
, pp. 455-476
-
-
Jouvet, M.1
-
33
-
-
0023945587
-
Evidence for histaminergic arousal mechanisms in the hypothalamus of cat
-
Lin JS, Sakai K and Jouvet M: Evidence for histaminergic arousal mechanisms in the hypothalamus of cat. Neuropharmacolgy 27, 111-122 (1988)
-
(1988)
Neuropharmacolgy
, vol.27
, pp. 111-122
-
-
Lin, J.S.1
Sakai, K.2
Jouvet, M.3
|