Effect of troglitazone on blood insulin levels after pancreas transplantation with systemic venous drainage in rats

Transplantation

Volumn 64, Issue 10, 1997, Pages 1476-1478

  Uchiyama, Kiyoshi ^a   Nakai, Ichiro ^a   Shimizu, Yoshihiro ^a   Mitsuo, Manabu ^a   Yasunami, Yohichi ^b   Oka, Takahiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TROGLITAZONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DOSE RESPONSE; GLUCOSE BLOOD LEVEL; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; RAT; VEIN BLOOD FLOW;

EID: 0030775364     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199711270-00018     Document Type: Article

References (14)

1. Diem P, Abid M, Redmon JB, Sutherland DE, Robertson RP. Systemic venous drainage of pancreas allografts as independent cause of hyperinsulinemia in type I diabetic recipients. Diabetes 1990; 39(5): 534.
2. Osei K, Cottrell DA, Henry ML, Tesi RJ, Ferguson RM, O'dorisio TM. Minimal model analysis of insulin sensitivity and glucose mediated glucose disposal in type-1 (insulin dependent) diabetic pancreas allograft recipients. Diabetologia 1992; 35: 676.
3. Marangou AG, Weber KM, Boston RC, et al. Metabolic consequences of prolonged hyperinsulinemia in humans: evidence for induction of insulin insensitivity. Diabetes 1986; 35: 1383.
4. Fujiwara T, Yoshioka S, Yoshioka T, Ushiyama I, Horikoshi H. Characterization of new oral antidiabetic agent CS-045. Diabetes 1988; 37(11): 1549.
5. Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM. Metabolic effects of new oral hypoglycemic agent CS045 in NIDDM subjects. Diabetes Care 1992; 15: 193.
6. Lee S, Tung KSK, Koopmans H, Chandler JG, Orloff MJ. Pancreaticoduodenal transplantation in the rat. Transplantation 1972; 13: 421.
7. Lundbaek K. Intravenous glucose tolerance as a tool in definition and diagnoses of diabetes mellitus. BMJ 1962; 2: 1507.
8. Osei K, Mitchell HL, O'Doriso TM. Physiologic and pharmacological stimulation of pancreatic islet hormone secretion on type diabetic pancreas allograft recipients. Diabetes 1990; 39: 1235.
9. Pagano G, Cavallo-Perin P, Cassader M. An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. J Clin Invest 1983; 72: 1814.
10. Elahi D, Clark BA, McAloon-Dyke M. Islet cell responses to glucose in human transplanted pancreas. Am J Physiol 1991; 261: E800.
11. Mitsuo M, Nakai I, Oda T, Shimizu Y, Oka T. Importance of venous drainage site of pancreas graft on carbohydrate and lipid metabolisms in streptozotocin induced diabetic rats. Transplant Proc 1994; 26: 485.
12. Tominaga M, Igarashi M, Daimon M, et al. Thiazolidinediones (AD-4833 and CS-045 improve hepatic insulin resistance in streptozotocin-induced diabetic rats. Endocrine J 1993; 40: 343.
13. Stout RW. Development of vascular lesions in insulin-treated animals fed a normal diet. BMJ 1970; 19: 685-687.
14. Abe H, Bandai A, Makuuchi M, et al. Hyperinsulinaemia accelerates accumulation of cholesterol ester in aorta of rats with transplanted pancreas. Diabetologia 1996; 39: 1276.