19-nor-10-azasteroids, a new class of steroid 5α-reductase inhibitors. 2. X-ray structure, molecular modeling, conformational analysis of 19-nor- 10-azasteroids and comparison with 4-azasteroids and 6-azasteroids

Journal of Medicinal Chemistry

Volumn 40, Issue 21, 1997, Pages 3466-3477

  Guarna, Antonio ^a   Occhiato, Ernesto G ^a   Machetti, Fabrizio ^a   Marrucci, Alessandro ^a   Danza, Giovanna ^a   Serio, Mario ^a   Paoli, Paola ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

19 NOR 10 AZASTEROID; AZASTEROID; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DOG; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; MALE; MOLECULAR MODEL; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

AZASTEROIDS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; TESTOSTERONE; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 0030774872     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970297k     Document Type: Article

References (40)

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