IgA from HIV+ haemophilic patients triggers intracellular signals coupled to the cholinergic system of the intestine

Clinical and Experimental Immunology

Volumn 110, Issue 2, 1997, Pages 189-195

  Sales, M E ^a   Sterin Borda, L ^a   De Bracco, M M E ^b   Rodriguez, M ^a   Narbaitz, M ^b   Borda, E ^a  

^a Centre de Estudios Farmacologicos y Botanicos   (Argentina)

^b INST DE INVEST HEMATOLOGICAS   (Argentina)

Author keywords

AIDS intestinal disease; Cholinergic receptors; HIV+ IgA; Muscarinic signalling

Indexed keywords

IMMUNOGLOBULIN A; ION CHANNEL;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CHOLINERGIC SYSTEM; CHOLINERGIC TRANSMISSION; EPITHELIUM CELL; HEMOPHILIA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOFLUORESCENCE; INTESTINE INNERVATION; INTESTINE MUCOSA; MALABSORPTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030774151     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1997.tb08316.x     Document Type: Article

References (33)

1. Laughon BE, Druckman DA, Vernon A et al. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology 1988; 94:984-93.
2. Ullrich R, Zeltz M, Heisse W et al. Small intestinal structure and function in patients with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy. Ann Intern Med 1989; 111:15-21.
3. Kapembwa MS, Batman PA, Fleming SC, Griffin GE. HIV enteropathy. Lancet 1989; 2:1521-2.
4. Holmgren J, Fryklund J, Larsson H. Gamma-interferon-mediated down-regulation of electrolyte secretion by intestinal epithelial cells: a local immune mechanism? Scand J Immunol 1989; 30:449-503.
5. de Bracco MME, Borda E, Galassi N et al. Autoantibodies in HIV-infected patients that modulate the cholinergic activity of heart and gut tissue. Autoimmunity 1993; 14:307-14.
6. Borda E, Sterin-Borda L, Vernava D et al. Parasympathomimetic activity of sera from HIV-infected hemophilic patients with or without diarrhea. Immunol Infect Dis 1993; 3:321-6.
7. Hosey MM. Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors. FASEB J 1992; 6:845-52.
8. 2. Amm J Reprod Immunol 1989; 20:147-52.
9. Zhang L, Horowitz B, Buxton ILO. Muscarinic receptors in canine colonic circular smooth muscle. I Coexistence of M2 and M3 subtypes. Mol Pharmacol 1991; 40:943-51.
10. Lowry OH, Rosebrough NJ, Fair AL, Randall RS. Protein measurement with the Polin phenol reagent. J Biol Chem 1951; 193:205-68.
11. Sterin-Borda L, Borda E, Fink S, de Bracco MME. Effect of phytohemagglutinin-stimulated human lymphocytes on isolated rat atria. Participation of lipoxygenase products of arachidonic acid metabolism. Naunyn Schmiedeberg's Arch Pharmacol 1983; 324:58-63.
12. Brown BL, Albaro JDM, Ekins RP, Sgherzi AM. A simple and sensitive saturation assay method for the measurement of adenosine 3′,5′-monophosphate. Biochem J 1971; 121:561-2.
13. Goin JC, Perez Leiros C, Borda E, Sterin-Borda L. Modification of cholinergic-mediated transmembrane signals by the interaction of human chagasic IgG with cardiac muscarinic receptors. Neuroimmunomodulation 1994; 1:284-91.
14. Berridge MJ, Downes CP, Hanley MP. Lithium amplifies agonist dependent phosphatidyl inositol response in brain and salivary glands. Biochem J 1982; 206:587-95.
15. Camusso JJ, Sterin-Borda L, Rodriguez M et al. Pharmacological evidence for the existence of different subtypes of muscarinic acetylcholine receptors for phosphoinositide hydrolysis in neonatal versus adult rat atria. J Lipid Mediators Signalling 1995; 12:1-10.
16. Granstrom E, Kindahl H. Radioimmunoassay of prostaglandins and thromboxanes. In: Frolich JC, ed. Advances in prostaglandin and thromboxane research. New York: Raven Press 1978; 5:119-210.
17. Mundson J, Rodbard D. LIGAND: a versatile computerized approach to characterization of ligand binding systems. Anal Biochem 1980; 107:220-39.
18. Morrow WJW, Isenberg DA, Sebol RE et al. AIDS virus infection and autoimmunity: a perspective of the clinical, immunological and molecular origins of autoallergic pathologies associated with HIV disease. Clin Immunol Immunopathol 1991; 58:163-80.
19. van der Leite J, Lange IMA, Vos JJE et al. Autoimmunity against blood cells in human immune deficiency virus (HIV) infection. Brit J Hematol 1987; 67:109-14.
20. Riera NE, Galassi N, Anselmo A et al. Leukoagglutinins in patients with hemophilia. Immunol Letters 1990; 24:107-12.
21. de la Barrera S, Fainboim L, Lugo S et al. Anti class II antibodies in AIDS patients and AIDS risk groups. Immunology 1987; 62:59-604.
22. Felder CC. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 1995; 9:619-25.
23. Mayer RJ, Marshall LA. New insights on mammalian phospholipase A2 (s): comparison of arachidonoyl-selective and non-selective enzymes. FASEB J 1993; 7:339-48.
24. 2: ion transport in the canine proximal colon. Am 3 Physiol 1991; 260:G481-G488.
25. Rehfeldt W, Mass R, Goppelt-Struebe M. Characterization of phospholipase A2 in monocytic cell lines. Functional and biochemical aspects of membrane association. Biochem J 1991; 276:631-6.
26. Reinhold SL, Prescott SM, Zimmerman GA, McIntyre TM. Activation of neutrophil phospholipase D by three separable mechanisms. FASEB J 1990; 4:208-14.
27. Cooke HJ. Neuroimmunomodulation of ion secretion by inflammatory mediators. Ann NY Acad Sci 1992; 664:346-52.
28. Goodwin JS, Webb DR. Regulation of immune response by prostaglandins. Clin Immunol Immunopathol 1980; 15:106-22.
29. 2 and cAMP phosphodiesterase levels in Kaposi's sarcoma: a virus against host defense mechanism. Res Commu Chem Pathol Pharmacol 1992; 78:249-52.
30. Fanger MW, Goldstine SN, Shen L. Cytofluorographic analysis of receptors for IgA on human polymorphonuclear leukocytes and monocytes and the correlation of receptor expression with phagocytosis. Mol Immunol 1983; 20:1019-27.
31. Ward PA. Neutrophils and adjuvant arthritis. Clin Exp Immunol 1997; 107:225-6.
32. 2: forgotten, promiscuous, capricious. Ann NY Acad Sci 1992; 664:248-59.
33. 2 in alterations of the β adrenergic system from rat eclamptic uterus. Biochem Pharmacol 1995; 50:1071-7.