Synthesis of a new carbocyclic nucleoside analog

Tetrahedron Letters

Volumn 38, Issue 36, 1997, Pages 6433-6436

  Bianco, Armandodoriano ^a   Mazzei, Raffaele Antonio ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC NUCLEOSIDE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030773841     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01470-6     Document Type: Article

References (20)

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2. b) White, E. L.; Parker, W. B.; Macy, L. J.; Shaddix, S. C.; McCaleb, G.; Secrist, J. A.; Vince, R.; Shannon, W. M., Biochem. Biophys. Res. Comm., 1989, 161, 393.
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7. c) Agrofoglio, L.; Suhas, E.; Farese, A.; Condom, R.; Challand, S. R.; Earl, R. A.; Guedj, R., Tetrahedron, 1994, 50, 10611, and references therein.
8. d) Tanaka, M., Norimine, Y., Fujita, T., Suemune, H., Sakai, K., J. Org. Chem., 1996, 61, 6952.
9. e) Vince, R., Pham, P., Nucleosides Nucleotides, 1995, 14, 2051.
10. f) Vince, R., Kilama, J., Pham, P., Beers, S., Nucleosides Nucleotides, 1995, 14, 1703.
11. g) Grumann, A., Marley, H., Taylor, R., Tetrahedron Letters, 1995, 7767.
12. h) Berranger, T., Langlois, Y., Tetrahedron Letters, 1995, 5523.
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14. 2O), δ: 147.3 (C-3), 130.8 (C-2), 81.8 (C-1), 62.0 (C-3′), 60.4 (C-4′), 60.2 (C-S″), 48.7 (C-4), 48.5 (C-5), 31.1 (C-5′). See also : Bianco, A., Guiso, M., Iavarone, C., Passacantilli, P., Trogolo, C., Tetrahedron, 1977, 33, 851.
15. 7: C 63.30, H 8.60; found C 63.18, H 8.68.
16. 8: C 62.71, H 8.24; found C 62.65, H 8.33.
17. a) Vorbruggen, H.; Höfle, G.,. Chem Ber., 1981, 114, 1256.
18. b) Vorbrüggen, H.; Bennua, B., Chem. Ber., 1981, 114, 1279, and references therein.
19. 8: C 60.96, H 7.37, N 5.69; found C 60.90, H 7.42, N 5.70.
20. 5: C 55.31, H 6.43, N 9.92; found C 55.20, H 6.51, N 9.83.