Lymphoid blast crisis during complete cytogenetic remission following interferon-α and hydroxyurea therapy

Acta Haematologica

Volumn 98, Issue 3, 1997, Pages 155-159

  Bose, S ^a   Chowdhyy, V P ^a   Saxena, R ^a   Kucheria, K ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Chronic myelogenous leukemia; Interferon therapy; Lymphoid blast crisis

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; HYDROXYUREA;

ADULT; ARTICLE; BLAST CELL CRISIS; BLAST TRANSFORMATION; BONE MARROW EXAMINATION; CASE REPORT; CHROMOSOME 22Q; CHROMOSOME 9Q; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOGENETICS; DIPLOIDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; KARYOTYPE; LEUKEMIA REMISSION; METAPHASE; ONCOGENE; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLAST CRISIS; FEMALE; HUMANS; HYDROXYUREA; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERFERON-ALPHA; KARYOTYPING; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MIDDLE AGED; PHILADELPHIA CHROMOSOME;

EID: 0030773325     PISSN: 00015792     EISSN: 14219662     Source Type: Journal    
DOI: 10.1159/000203611     Document Type: Article

References (34)

1. Rowley JD: A new consistent chromosomal abnormality in chronic myelogenous leukemia. Leukemia identified by quinacrine fluorescence and Giemsa staining. Nature 1973:243: 290-293.
2. de Klein A, Gcurts van Kessel AG, Grosveld G, Bartram CR, Hagemeijer A, Bootsma D, Spurr NK, Heister Kemp N, Groffen J, Stephenson JR: A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukemia. Nature 1982; 300:765-767.
3. Heisterkamp N, Stephenson JR, Groffen J, Hansen PF. de Klein A, Bartram CR, Grosveld G: Localization of the c-abl oncogene adjacent to a translocation breakpoint in chronic myelocytic leukemia. Nature 1983;306:239-242.
4. Kantarjian HM, Keating MJ, Walters RS, Me Credie KB, Smith TL, Talpaz M, Beran M. Cork A, Trujillo JM, Freireich EJ: Clinical and prognostic features of Philadelphia chromosome-negative chronic myelogenous leukemia. Cancer 1986;58:2023-2030.
5. Bartram CR: Rearrangements of c-abl and bcr genes in Ph'-negative CML and Ph-positive acute leukemias. Leukemia 1988;2:63-69.
6. Champlin RE, Golde DW: Chronic myelogenous leukemia - Recent advances. Blood 1985; 65:1039-1047.
7. Tien HF, Chuang SM, Wang CH, Lee FT, Chien SH. Chen YC, Shen MC, Liu CH: Chromosomal characteristics of the Ph-positive chronic myelogenous leukemia in transformation - A study of 23 Chinese patients in Taiwan. Cancer Genet Cytogenet 1989:39:89-97.
8. Hagemeijer A, Smit EMI, Lowenberg B, Abels J: Chronic myeloid leukemia with permanent disappearance of Ph chromosome and development of new clonal subpopulations. Blood 1979;53:1-14.
9. Smadja N, Krulik M. Audebcrt AA, de Gra-mont A, Debray J: Spontaneous regression of cytogenetic and haematologic anomalies in Ph-positive chronic myelogeneous leukaemia. Br J Haematol 1989;63:257-262.
10. Sokal JE, Gockcrman JP, Bigner SH: Evidence for a selective antileukemic effect of cytosine arabinosidc in chronic granulocytic leukemia. Leukemia Res 1988;12:453-458
11. Fegan C, Morgan G, Whittaker JA: Spontaneous remission in a patient with chronic myeloid leukemia. Br J Haematol 1989:72:594-595.
12. Goldman JM, Apperley JF, Jones LM, Marcus RE, Goolden AWG, Batchelor JR. Hale G, Waldmann H, Reid CD. Hows JM. Gordon-Smith EF, Catovsky D, Galton DAG: Bone marrow transplantation for chronic myeloid leukemia. N Engl J Med 1986;314:202-207.
13. Talpaz M, Kantarjian H, Kurzrock R, Trujillo JM, Gutterman JU: Interferon alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Ann Intern Med 1991; 114:532-538.
14. Lazaridou A, Chase A, Melo J, Garicochea B, Diamond J, Goldman J: Lack of reciprocal translocation in BCR-ABL positive Ph-negative chronic myeloid leukaemia. Leukemia 1994;8:454-457.
15. Garicochea B, Chase A, Lazaridou A. Goldman JM: T lymphocytes in chronic myelogenous leukemia (CML): No evidence of the BCR/ABL fusion gene detected by fluorescence in situ hybridization in 14 patients. Leukemia 1994;8:1197-1201.
16. Opalka B, Wandl UB, Becher R, Kloke O, Nagel-Hiemke M, Moritz T. Beere U, Sceber S, Niederle N: Minimal residual disease in patients with chronic myelogenous leukemia undergoing long-term treatment with recombinant interferon alpha 2b alone or in combination with interferon gamma. Blood 1991;78: 2188-2191.
17. Kloke O, Niederle N, Qiu JY, Wandl U, Moritz T, Nagechiemke M, Hawig I, Opalka B, Seeber S, Becher R: Impact of interferon alpha induced cytogenetic improvement on survival in chronic myelogenous leukemia following interferon therapy. Br J Haematol 1993;83:399-403.
18. The Italian Cooperative Study Group on Chronic Myelogenous Leukemia: Interferon alpha-23 compared with conventional chemotherapy for the treatment of chronic myeloid leukemia. N Engl J Med 1994;330:820-825.
19. Hehlmann R, Heimpel H, Hasford J, Kolb HJ, Pralle H, Hossfeld DK, Queisser W, Löffler H, Hochhaus A, Heinze B, Georgii A, Bartram CR, Griesshammer M, Bergmann L, Essers U, Falge C, Queisser U, Meyer P., Schmitz N, Eimermacher H, Wolther F, Fett W, Kleeberg UR, Kabisch A, Neri C, Zimmermann R, Meuret G, Tichelli A, Kanz L, Tiggs FJ, Shmid L, Brockhaus W, Toblcr A, Reiter A, Pcrker M, Emmerich B, Vcrpoort K, Zankovich R, v Wussow P, Prummer O, Thiele J, Burhr T, Ansari H, German CML Study Group: Randomized comparison of interferon alpha with busulphan and hydroxyurea in chronic myelogenous leukemia (CML). Blood 1994:84:4064-4077.
20. Kantarjian HM, Smith TL, O’Brien S, Beran M, Pierce S, Talpaz M: Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon alpha therapy. Ann Intern Med 1995;122:254-261.
21. Allan NC. Richards SM. Shepherd PCA: UK Medical Research Council randomised, multicentre trial of interferon-alpha n 1 for chronic myeloid leukemia: Improved survival irrespective of cytogenetic response. Lancet 1995:345: 1392-1397.
22. Dhingra K, Kurzrock R. Kantarjian H, Baine R, Eastman PS, Ku S, Gutterman JU, Talpaz M: Minimal residual disease in interferon-treated chronic myelogenous leukemia: Results and pitfalls of analysis based on polymerase chain reaction. Leukemia 1992;6:754-760.
23. Zhao L, Kantarjian HM, Van Oort J, Cork A, Trujillo JM, Liang JC: Detection of CML patients in complete remission after interferon treatment. Leukemia 1993;7:168-171.
24. Hochhaus A, Lin F, Reiter A, Skladny H, van Rhee F, Shepherd PCA, Allan NC, Hchlmann R, Goldman JM, Cross NCP: Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-alpha. Br J Haematol 1995;91:126-131.
25. Appelbaum FR, Najfcld V, Singer JN: Chronic myelogenous leukemia; prolonged survival with spontaneous decline in the frequency of PH'-positive cells and subsequent development of mixed PH'-positive and PH'-negative blast crisis. Cancer 1983;51:149-153.
26. O'Brien S, Witt R, Talpaz M, Kantarjian H: Extramedullary blast crisis in a patient with Ph' chromosome-positive chronic myelogenous leukemia in complete cytogenetic remission. Cancer 1990;67:1946-1949.
27. Labardini L: Late appearance of Philadelphia chromosome in two patients with chronic myelogenous leukemia. Blood 1980;56:812-814.
28. Fialkow PJ, Martin PJ, Najfeld V, Penfold GK, Jacobsen PJ, Hensen JA: Evidence for a multi-step pathogenesis of chronic myelogenous leukemia. Blood 1981;58:158-163.
29. Lisker R. Cases L. Mutchinick O, Lopez-Ariza B, Lambardini J: Patient with chronic myelogenous leukemia and late appearing Philadelphia chromosome. Can Genet Cytogenet 1982;6: 275-277.
30. Fialkow PJ, Jacobson RJ, Papayannopoulou T: Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am J Med 1977:63:125-130.
31. Martin PJ, Najfeld V, Hansen JA, Penfold GK, Jacobson RJ. Fialkow PJ: Involvement of the B-lymphoid system in chronic myelogenous leukemia. Nature 1980;287:49-50.
32. Raskind WH, Fialkow PJ: The use of cell markers in the study of human haematopoietic neoplasia. Adv Cancer Res 1987;49:127-167.
33. Kuriyama K, Gale PP, Tomonage M, Ikeda S, Yao E, Klisak I, Whelan K, Ycleir H, Ichimaru M, Spurkes RG. Drezasen O: CML-TI: A cell line derived from T-lymphocyte acute phase of chronic myelogenous leukemia. Blood 1989; 74:1381-1387.
34. Tcffcri A, Schad CR, Pruthi RK, Ahmann GJ, Spurbeck JL. Dewald GW: Fluorescent in situ hybridization studies of lymphocytes and neutrophils in chronic granulocytic leukemia. Cancer Genet Cytogenet 1995,83:61-64.