Does isatin interact with rat brain monoamine oxidases in vivo?

Neuroscience Letters

Volumn 233, Issue 1, 1997, Pages 58-60

  Panova, N G ^a   Zemskova, M A ^a   Axenova, L N ^a   Medvedev, A E ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Anxiety; Endogenous regulator; Isatin; Monoamine oxidase; Monoamine oxidase inhibitors; Rat brain; Sedation

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ANTICONVULSIVE AGENT; ISATIN; MONOAMINE OXIDASE INHIBITOR; PHENELZINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; AUDIOGENIC SEIZURE; CONVULSION; DATA ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; ENZYME INHIBITORS; ISATIN; MALE; MONOAMINE OXIDASE; PHENELZINE; RATS;

EID: 0030772761     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00597-1     Document Type: Article

References (18)

1. Bhattacharya, S.K. and Acharya, S.B., Further investigations on the anxiogenic effects of isatin, Biogen. Amines, 9 (1993) 453-463.
2. Bhattacharya, S.K., Chakrabarti, A., Sandler, M. and Glover, V., Anxyolytic activity of intraventricularly administered atrial natriuretic peptide in the rat, Neuropsychopharmacology, 15 (1996) 199-206.
3. Bhattacharya, S.K., Clow, A., Przyborowska, A., Halket, J., Glover, V. and Sandler, M., Effect of aromatic acids, pentylene tetrazole and yohimbine on isatin and tribulin activity in rat brain, Neurosci. Lett., 132 (1991) 44-46.
4. Cesura, A.M. and Pletscher, A., The new generation of monoamine oxidase inhibitors, Prog. Drug Res., 38 (1992) 171-297.
5. Clow, A., Glover, V. and Sandler, M., Stress reduces in vivo inhibition of monoamine oxidase by phenelzine in rat brain, Neurosci. Lett., 107 (1989) 331-334.
6. Glover, V., Halket, J., Watkins, P.J., Clow, A., Goodwin, B.L. and Sandler, M., Isatin: identity with the purified monoamine oxidase inhibitor, tribulin, J. Neurochem., 51 (1988) 656-659.
7. Glover, V., Medvedev, A.E. and Sandler, M., Isatin is a potent antagonist of guanylate cyclase-coupled atrial natriuretic peptide receptors, Life Sci., 57 (1995) 2073-2079.
8. Green, A.L., Assessment of the potency of reversible MAO inhibitors in vivo. In K.F. Tipton, P. Dosters and M. Strolin Benedetti (Eds.), Monoamine Oxidase and Disease: Prospect for Therapy with Reversible Inhibitors, Academic Press, London, 1984, pp. 73-82.
9. Hamaue, N., Minami, M., Kanamaru, Y., Togashi, M., Monma, Y., Ishikura, M., Mahara, R., Yamazaki, N., Saito, H. and Parvez, S.H., Endogenous monoamine oxidase (MAO) inhibitor (tribulin-like activity) in the brain and urine of stroke-prone SHR, Biogen. Amines, 8 (1992) 401-412.
10. Hamaue, N., Minami, M., Kanamaru, Y., Ishikura, M., Yamazaki, N., Saito, H. and Parvez, S.H., Identification of isatin, an endogenous MAO inhibitor in the brain of stroke-prone SHR, Biogen. Amines, 10 (1994) 99-110.
11. Kumar, R., Bansal, R.C. and Mahmood, A., In vivo effects of isatin on certain enzymes, lipids, and serotonergic system of rat brain, Ind. J. Med. Res., 100 (1994) 246-250.
12. McIntyre, I.M. and Norman, T.R., Serotonergic effects of isatin: an endogenous MAO inhibitor related to tribulin, J. Neural. Transm. (Gen. Sect.), 79 (1990) 35-40.
13. Medvedev, A.E., Clow, A., Sandler, M. and Glover, V., Isatin: a link between natriuretic peptides and monoamines?, Biochem. Pharmacol., 52 (1996) 385-391.
14. Medvedev, A.E., Gorkin, V.Z., Fedotova, I.B. and Semiokhina, A.F., Monoamine oxidase inhibitors as anticonvulsants, Can. J. Physiol. Pharmacol., 71 (Suppl.) (1994) 400 (Abstract).
15. Medvedev, A.E., Ivanov, A.S., Kamyshanskaya, N.S., Kirkel, A.Z., Moskvitina, T.A., Gorkin, V.Z., Li, N.Y. and Marshakov, V.Y., Interaction of indole derivatives with monoamine oxidase A and B. Studies on the structure-inhibitory activity relationship, Biochem. Mol. Biol. Int., 36 (1995) 113-122.
16. Medvedev, A.E., Kirkel, A.Z., Kamyshanskaya, N.S., Moskvitina, T.A., Axenova, L.N., Gorkin, V.Z., Andreeva, N.I., Golovina, S.M. and Mashkovsky, M.A., Monoamine oxidase inhibition by novel antidepressant tetrindole, Biochem. Pharmacol., 47 (1994) 303-308.
17. Watkins, P., Clow, A., Glover, V., Halket, J., Przyborowska, A. and Sandler, M., Isatin, regional distribution in rat brain and tissues, Neurochem. Int., 17 (1990) 321-323.
18. Yuwiller, A., The effect of isatin (tribulin) on metabolism of indoles in rat brain and pineal: in vitro and in vivo studies, Neurochem. Res., 15 (1990) 95-100.