The effects of T cell subpopulations and recombinant interleukin (IL)-2 on peripheral B cell function in patients with myasthenia gravis

Human Antibodies

Volumn 8, Issue 2, 1997, Pages 90-94

  Zhang, Jian ^a,c   Zhou, Wen Bin ^a   Wang, Hong Lin ^a   Guo, Shi Shi ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Anti AChR antibody; B cell differentiation; IL 2; Myasthenia gravis; T cell subpopulation

Indexed keywords

RECOMBINANT INTERLEUKIN 2;

ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; MYASTHENIA GRAVIS; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030772106     PISSN: 10932607     EISSN: None     Source Type: Journal    
DOI: 10.3233/hab-1997-8206     Document Type: Article

References (36)

1. Linstrom JM, Seybold ML, Lennon VA, Whittingham S, Duane DD. Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value. Neurology 1976; 26: 1054
2. Compston DAS, Vincent A, Newson-Davis J, Batchelor JR. Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain 1980; 103: 579
3. Almon RR, Andrew CG, Appel SH. Serum globulin in myasthenia gravis: Inhibition of a-bungarotoxin binding to acetylcholine receptors. Science 1974; 186: 55
4. Vincent A, Newson-Davis J. Anti-acetylcholine receptor antibodies. J Neurol Neurosurg Psychiatry 1980; 43: 590
5. Drachman DB. The biology of myasthenia gravis. Annu Rev Neurosci 1981; 4: 195
6. Engel AG. Morphological and immunopathological findings in myasthenia gravis and in congenital myasthenic syndromes. J Neurol Neurosurg Psychiatry 1980; 43: 577
7. Lisak RP, Levinson AI, Zeriman B, Kornstein MJ. In vitro synthesis of IgG and antibodies to AChR by peripheral and thymic lymphocytes. Ann NY Acad Sci 1987; 505: 39
8. Shinomiya N, Yata J. B and T cell involvement in anti-acetylcholine receptor antibody formation in myasthenia gravis. Clin Exp Immunol 1981; 46: 277
9. Shinomiya N, Yata J, Sasazuki T. T cell subsets regulating anti-acetylcholine receptor-antibody formation in myasthenia gravis and characterization of suppressor T-cell factors involved. Clin Immunol Immunopathol 1984; 33: 182
10. Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor: Partial characterization of the receptor. Nature 1982; 300: 267
11. Smith KA. Interleukin-2. Ann Rev Immunol 1984; 2: 319
12. Oosterhuis HHGH. Studies in myasthenia gravis. Part 1. A clinical study of 180 patients. J Neurol Sci 1964; 1: 512
13. Yoshikawa N, Morita T, Resetkova E, Arreaza G, Volpé R. Reduced activation of suppressor T lymphocyte by specific antigens in autoimmune thyroid disease. J Endocrinol Invest 1993; 15: 609
14. Kuks JBM, Limburg PC, Oosterhuis HJG, The TH. Antibodies to acetylcholine receptors in myasthenia gravis. In vitro synthesis by peripheral blood lymphocytes before and after thymectomy. Clin Exp Immunol 1992; 87: 246
15. Möller SA, Borrebaeck CAR. A filter immuno-plaque assay for the detection of antibody-secreting cells in vitro. J Immunol Meth 1985; 79: 195
16. Engleman EG, Benike CJ, Glickman E. Evans RL. Antibodies to membrane structures that distinguish suppressor/cytotoxic and helper T lymphocyte subpopulations block the mixed leukocyte reaction in man. J Exp Med 1981; 154: 193
17. + suppressor cells. J Clin Immunol 1984; 4: 395
18. Skolnik PR, Lisak RP, Zeriman B. Monoclonal antibody analysis of blood T-cell subsets in myasthenia gravis. Ann Neurol 1981; 11: 170
19. Mischak RP, Dau PC, Gonzalez RL, Spitler LE. In vitro testing of suppressor cell activity in myasthenia gravis. In: Dau PC, ed. Plasma-pheresis and the Immunobiology of Myasthenia Gravis. Boston: Houghton Mifflin, 1979: pp. 72
20. Holfeld R, Toyka KV, Heininger K, Gross-Wilde H, Kalies I. Autoimmune human T lymphocytes specific for acetylcholine receptor. Nature 1984; 310: 244
21. Wekerle H, Holfeld R, Ketelsen UP. Thymic myogenesis, T-lymphocytes and the pathogenesis of myasthenia gravis. Ann NY Acad Sci 1981; 377: 455
22. Ashana D, Fujii Y, Huston G, Linstrom J. Regulation of antibody production by helper T cell clones in experimental autoimmune myasthenia gravis is mediated by IL-4 and antigen-specific T cell factors. Clin Immunol Immunopathol 1993; 67: 240
23. Wang ZY, Link H, Ljundahl Å, Hÿjeberg B, Link, Qiao J, Melms A, Olsson T. Induction of IFN-γ, IL-4 and TGF-β in rats orally tolerized against experimental autoimmune myasthenia gravis. Cell Immunol 1994; 157: 353
24. Christadoss P, Dauphinee M. Immunotherapy for myasthenia gravis: A murine model. J Immunol 1986; 136: 2437
25. Waldor M, Sriram S, McDevitt HO, Steinman L. In vivo therapy with monoclonal anti I-A antibody suppresses immune response to acetylcholine receptor. Proc Natl Acad Sci USA 1983; 80: 2713
26. Lider OT, Reshef T, Beraud E, Ben-Nun A, Cohen IR. Anti-idiotypic network induced by T cell vaccination against experimental autoimmune encephalomyelitis. Science 1981; 239: 181
27. Sun D, Qin Y, Chluba J, Epplen JT, Wekerle H. Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature 1988; 332: 843
28. Lohse AW, Mor F, Karin N, Cohen IR. Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells. Science 1986; 244: 820
29. + T lymphocytes. Biochemistry 1989; 341: 748
30. + cells in myasthenia gravis patients and in healthy controls. J Immunol 1996; 154: 1508
31. + T cell response to the human acetylcholine receptor α subunit in myasthenia gravis: A study with synthetic peptides. J Immunol 1990; 144: 1276
32. + T-epitope repertoire on the human acetylcholine receptor α subunit in severe myasthenia gravis. Neurology 1992; 42: 1092
33. Manfredi AA, Protti MP, Dalton WM, Howard JF, Conti-Tronconi BM. T helper cell recognition of muscle acetylcholine receptor in myasthenia gravis: Epitopes on the γ and δ subunits. J Clin Invest 1993; 92: 1055
34. + T cells suppresses the development of experimental autoimmune myasthenia gravis in Lewis rats. Eur J Immunol 1995, 25: 1191
35. + T cells are essential to induce experimental autoimmune myasthenia gravis. J Exp Med 1996; 184: 349
36. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17: 138