The effect of 15-HPETE on airway responsiveness and pulmonary cell recruitment in rabbits

British Journal of Pharmacology

Volumn 122, Issue 2, 1997, Pages 249-256

  Riccio, M M ^a,b   Matsumoto, T ^a   Adcock, J J ^a   Douglas, G J ^a   Spina, D ^a   Page, C P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Sandoz Institute   (United Kingdom)

Author keywords

15 HPETE; Airways; Capsaicin; Histamine; Lipoxygenase

Indexed keywords

15 HYDROPEROXYARACHIDONIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; ATROPINE; CAPSAICIN; HISTAMINE; TYROSYL DEXTRO ARGINYLGLYCYL 4 NITROPHENYLALANYLPROLINAMIDE;

AIRWAY; ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; INFLAMMATORY INFILTRATE; LUNG ALVEOLUS CELL; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ATROPINE; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CAPSAICIN; HISTAMINE; HYDROXYEICOSATETRAENOIC ACIDS; LEUKOTRIENES; LIPID PEROXIDES; LUNG; MALE; MUSCARINIC ANTAGONISTS; RABBITS;

EID: 0030770912     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701379     Document Type: Article

References (52)

1. ADCOCK, J.J. & GARLAND, L.G. (1993). The contribution of sensory reflexes and "hyperalgesia" to airway hyperresponsiveness. In Airway Hyperresponsiveness: Is it Really Important for Asthma, ed. Page, C.P. & Gardiner, P.J. pp. 234-255. Oxford: Blackwell Scientific Publications.
2. BALLATI, L., EVANGELISTA, S. & MANZINI, S. (1992). Repeated antigen challenge induced airway hyperresponsiveness to neurokinin A and vagal non-adrenergic, non-cholinergic (NANC) stimulation in guinea pigs. Life Sci., 51, PL119-24.
3. BELVISI, M.G., PATACCHINI, R., BARNES, P.J. & MAGGI, C.A. (1994). Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences. Br. J. Pharmacol., 111, 103-110.
4. BOICHOT, E., BIYAH, K., GERMAIN, N., EMONDS-ALT, X., LAGENTE, V. & ADVENIER, C. (1996). Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs. Eur. Respir. J., 9, 1445-1450.
5. BOICHOT, E., GERMAIN, N., LAGENTE, V. & ADVENIER, C. (1995). Prevention by the tachykinin NK2 receptor antagonist, SR 48968, of antigen-induced airway hyperresponsiveness in sensitized guinea-pigs. Br. J. Pharmacol., 114, 259-261.
6. BRADDING, P., REDINGTON, A.E., DJUKANOVIC, R., CONRAD, D.J. & HOLGATE, S.T. (1995). 15-Lipoxygenase immunoreactivity in normal and in asthmatic airways. Am. J. Respir. Crit. Care Med., 151, 1201-1204.
7. CHOUDRY, N.B., GRAY, S.J., POSNER, J. & FULLER, R.W. (1991). The effect of 443C81, a mu opioid receptor agonist, on the response to inhaled capsaicin in healthy volunteers. Br. J. Clin. Pharmacol., 32, 633-636.
8. CONRAD, D.J., KUHN, H., MULKINS, M., HIGHLAND, E. & SIGAL, E. (1992). Specific inffammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc. Natl. Acad. Sci. U.S.A., 89, 217-221.
9. COYLE, A.J., PERRETTI, F., MANZINI, S. & IRVIN, C.G. (1994). Cationic protein-induced sensory nerve activation: role of substance P in airway hyperresponsiveness and plasma protein extravasation. J. Clin. Invest., 94, 2301-2306.
10. DAFFONCHIO, L., HERNANDEZ, A., GALLICO, L. & OMINI, C. (1990). Airway hyperreactivity induced by active cigarette smoke exposure in guinea-pigs: possible role of sensory neuropeptides. Pulm. Pharmacol., 3, 161-166.
11. DAHLEN, S.E., RAUD, J., SERHAN, C.N., BJORK, J. & SAMUELSSON, B. (1987). Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. Acta Physiol. Scand., 130, 643-647.
12. FERREIRA, S.H., LORENZETTI, B.B., BRISTOW, A.F. & POOLE, S. (1988). Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature, 334, 698-700.
13. FOLLENFANT, R.L., NAKAMURA-CRAIG, M. & GARLAND, L.G. (1990). Sustained hyperalgesia in rats evoked by 15-hydroperoxyeicosatetraenoic acid is attenuated by the protein kinase inhibitor H-7. Br. J. Pharmacol., 99, 289P.
14. GOETZL, E.J., PHILLIPS, M.J. & GOLD, W.M. (1983). Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. J. Exp. Med., 158, 731-737.
15. HANSSON, A., SERHAN, C.N., HAEGGSTROM, J., INGELMAN SUNDBERG, M. & SAMUELSSON, B. (1986). Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid. Biochem. Biophys. Res. Commun., 134, 1215-1222.
16. HERD, C.M., GOZZARD, N. & PAGE, C.P. (1995). Capsaicin pretreatment prevents the development of antigen-induced airway hyperresponsiveness in neonatally immunised rabbits. Eur. J. Pharmacol., 282, 111-119.
17. HOPKINS, N.K., OGLESBY, T.D., BUNDY, G.L. & GORMAN, R.R. (1984). Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells. J. Biol. Chem., 259, 14048-14053.
18. HUNTER, J.A., FINKBEINER, W.E., NADEL, J.A., GOETZL, E.J. & HOLTZMAN, M.J. (1985). Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc. Natl. Acad. Sci. U.S.A., 82, 4633-4637.
19. JARREAU, P.H., D'ORTHO, M.P., BOYER, V., HARF, A. & MACQUIN MAVIER, I. (1994). Effects of capsaicin on the airway responses to inhaled endotoxin in the guinea pig. Am. J. Respir. Crit. Care Med., 149, 128-133.
20. JOHN, C., BRUNNER, S. & TANAKA, D.T. (1993). Neuromodulation mediated by neurokinin-1 subtype receptors in adult rabbit airways. Am. J. Physiol., 263, L228-33.
21. JOHNSON, H.G., MCNEE, M.L. & SUN, F.F. (1985). 15-Hydroxyeicosatetraenoic acid is a potent inflammatory mediator and agonist of canine tracheal mucus secretion. Am. Rev. Respir. Dis., 131, 917-922.
22. KARLSSON, J.A., ZACKRISSON, C., SJOLIN, C. & FORSBERG, K. (1991). Cigarette smoke-induced changes in guinea-pig airway responsiveness to histamine and citric acid. Acta Physiol. Scand., 142, 119-125.
23. KIRSCH, C.M., SIGAL, E., DJOKIC, T.D., GRAF, P.D. & NADEL, J.A. (1988). An in vivo chemotaxis assay in the dog trachea: evidence for chemotactic activity of 8,15-diHETE. J. Appl. Physiol., 64, 1792-1795.
24. KOTO, H., AIZAWA, H., TAKATA, S., INOUE, H. & HARA, N. (1995). An important role of tachykinins in ozone-induced airway hyperresponsiveness. Am. J. Respir. Crit. Care Med., 151, 1763-1769.
25. LAI, C.K., PHILLIPS, G.D., JENKINS, J.R. & HOLGATE, S.T. (1990a). The effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid (15-HETE) on airway calibre and non-specific responsiveness in normal and asthmatic human subjects. Eur. Respir. J., 3, 38-45.
26. LAI, C.K., POLOSA, R. & HOLGATE, S.T. (1990b). Effect of 15-(s)-hydroxyeicosatetraenoic acid on allergen-induced asthmatic responses. Am. Rev. Respir. Dis., 141, 1423-1427.
27. LENDRUM, A.C. (1944). The staining of eosinophil polymorphs and enterochromaffic cells in histological sections. J. Pathol. Bact., 56, 441-445.
28. MAREK, W., POTTHAST, J.J.W., MARCZYNSKI, H. & BAUR, X. (1996). Role of substance P and neurokinin A in toluene diisocyanate-induced increased airway responsiveness in rabbits. Lung, 174, 83-97.
29. MEINI, S., EVANGELISTA, S., GEPPETTI, P., SZALLASI, A., BLUMBERG, P.M. & MANZINI, S. (1992). Pharmacologic and neurochemical evidence for the activation of capsaicin-sensitive sensory nerves by lipoxin A4 in guinea pig bronchus. Am. Rev. Respir. Dis., 146, 930-934.
30. MIZZUGUCHI, M., FUJIMURA, M., AMEMIYA, T., NISHI, K., OHKA, T. & MATSUDA, T. (1996). Involvement of NK2 receptors rather than NK1 receptors in bronchial hyperresponsiveness induced by allergic reaction in guinea-pigs. Br. J. Pharmacol., 117, 443-448.
31. MORITA, E., SCHRODER, J.M. & CHRISTOPHERS, E. (1990). Identification of a novel and highly potent eosinophil chemotactic lipid in human eosinophils treated with arachidonic acid. J. Immunol., 144, 1893-1900.
32. NADEL, J.A., CONRAD, D.J., UEKI, I.F., SCHUSTER, A. & SIGAL, E. (1991). Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells. J. Clin. Invest., 87, 1139-1145.
33. NAKAMURA-CRAIG, M. & GILL, B.K. (1991). Effect of neurokinin A. substance P and calcitonin gene related peptide in peripheral hyperalgesia in the rat paw. Neurosci. Lett., 124, 49-51.
34. NAKAMURA-CRAIG, M. & SMITH, T.W. (1989). Substance P and peripheral inflammatory hyperalgesia. Pain, 38, 91-98.
35. PERRETTI, F., BALLATI, L., MANZINI, S., MAGGI, C.A. & EVANGELISTA, S. (1995). Antibronchospastic activity of MEN10,627, a novel tachykinin NK2 receptor antagonist, in guinea-pig airways. Eur. J. Pharmacol., 273, 129-135.
36. PERRETTI, F. & MANZINI, S. (1993). Activation of capsaicin-sensitive sensory fibers modulates PAF-induced bronchial hyperresponsiveness in anesthetized guinea pigs. Am. Rev. Respir. Dis., 148, 927-931.
37. RICCIO, M.M., MANZINI, S. & PAGE, C.P. (1993). The effect of neonatal capsaicin on development of bronchial hyperresponsiveness in allergic rabbits. Eur. J. Pharmacol., 232, 89-97.
38. SAFIEH-GARABEDIAN, B., POOLE, S., ALLCHORNE, A., WINTER, J. & WOOLF, C.J. (1995). Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br. J. Pharmacol., 115, 1265-1275.
39. SAMUELSSON, B., DAHLEN, S.E., LINDGREN, J.A., ROUZER, C.A. & SERHAN, C.N. (1987). Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science, 237, 1171-1176.
40. SCHWENK, U., MORITA, E., ENGEL, R. & SCHRODER, J.M. (1992). Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid. J. Biol. Chem., 267, 12482-12488.
41. SERHAN, C.N., HAMBERG, M. & SAMUELSSON, B. (1984a). Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. Biochem. Biophys. Res. Commun., 118, 943-949.
42. SERHAN, C.N., HAMBERG, M. & SAMUELSSON, B. (1984b). Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc. Natl. Acad. Sci. U.S.A., 81, 5335-5339.
43. SHAK, S., PEREZ, H.D. & GOLDSTEIN, I.M. (1983). A novel dioxygenation product of arachidonic acid possesses potent chemotactic activity for human polymorphonuclear leukocytes. J. Biol. Chem., 258, 14948-14953.
44. SIGAL, E. & NADEL, J.A. (1991). The airway epithelium and arachidonic acid 15-lipoxygenase. Am. Rev. Respir. Dis., 143, S71-4.
45. SPINA, D., MCKENNIFE, M.G., COYLE, A.J., SEEDS, E.A., TRAMONTANA, M., PERRETTI, F., MANZINI, S. & PAGE, C.P. (1991). Effect of capsaicin on PAF-induced bronchial hyperresponsiveness and pulmonary cell accumulation in the rabbit. Br. J. Pharmacol., 103, 1268-1274.
46. TANAKA, D.T., ANDO, R.E., LARSEN, G.L. & IRVIN, C.G. (1991). Cholinergic mechanisms involved with histamine hyperreactivity in immune rabbit airways challenged with ragweed antigen. Am. Rev. Respir. Dis., 144, 70-75.
47. TANAKA, D.T. & GRUNSTEIN, M.M. (1986). Effect of substance P on neurally mediated contraction of rabbit airway smooth muscle. J. Appl. Physiol., 60, 458-463.
48. TEPPER, J.S., COSTA, D.L., FITZGERALD, S., DOERFLER, D.L. & BROMBERG, P.A. (1993). Role of tachykinins in ozone-induced acute lung injury in guinea pigs. J. Appl. Physiol., 75, 1404-1411.
49. THOMPSON, J.E., SCYPINSKI, L.A., GORDON, T. & SHEPPARD, D. (1987). Tachykinins mediate the acute increase in airway responsiveness caused by toluene diisocyanate in guinea pigs. Am. Rev. Respir. Dis., 136, 43-49.
50. TURK, J., MASS, R.L., BRASH, A.R., ROBERTS, L.J.I. & OATES, J.A. (1982). Arachidonic acid 15-lipoxygenase products from human eosinophils. J. Biol. Chem., 257, 7068-7076.
51. WHITE, D.M., BASBAUM, A.I., GOETZL, E.J. & LEVINE, J.D. (1990). The 15-lipoxygenase product, 8R,15S-diHETE, stereospecitically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat. J. Neurophysiol., 63, 966-970.
52. WOOLF, C.J., SAFIEH GARABEDIAN, B., MA, Q.P., CRILLY, P. & WINTER, J. (1994). Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience, 62, 127-331.