Optimization of conditions for conversion of tylosin to a novel antibiotic, acetyl-isovaleryl tylosin (AIV), by Streptomyces thermotolerans and scale-up to 200-liter pilot-scale fermentor

Journal of Fermentation and Bioengineering

Volumn 84, Issue 1, 1997, Pages 77-81

  Huang, Guowei ^a   Okamoto, Rokuro ^b   Hikita, Atsushi ^c   Park, Yongsoo ^c   Okabe, Mitsuyasu ^c  

^a GIFU UNIVERSITY   (Japan)

^b MERCIAN CORPORATION   (Japan)

^c SHIZUOKA UNIVERSITY   (Japan)

Author keywords

Acetyl isovaleryl tylosin; Bioconversion; Streptomyces thermotolerans; Tylosin

Indexed keywords

ANTIBIOTICS; BACTERIA; CELL CULTURE; COMPOSITION; FERMENTATION; OXYGEN; PH; TEMPERATURE;

ACETYL ISOVALERYL TYLOSIN; STREPTOMYCES THERMOTOLERANS; TYLOSIN;

BIOCONVERSION;

ACETYLISOVALERYLTYLOSIN; TYLOSIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM CULTURE; BIOTRANSFORMATION; CULTURE MEDIUM; DRUG ACETYLATION; DRUG SYNTHESIS; FERMENTATION; NONHUMAN; STREPTOMYCES; STREPTOMYCES THERMOTOLERANS;

BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES THERMOTOLERANS;

EID: 0030770773     PISSN: 0922338X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0922-338X(97)82790-0     Document Type: Article

References (7)

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