Dedifferentiation of atrial cardiomyocytes as a result of chronic atrial fibrillation

American Journal of Pathology

Volumn 151, Issue 4, 1997, Pages 985-997

  Ausma, Jannie ^a,d   Wijffels, Maurits ^a   Van Eys, Guillaume ^a   Koide, Masafumi ^b   Ramaekers, Frans ^a   Allessie, Maurits ^a   Borgers, Marcel ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b CHUBU NATIONAL HOSPITAL   (Japan)

^c JANSSEN RESEARCH FOUNDATION   (Belgium)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CARDIOTIN; CONNECTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVERSION; CELL DIFFERENTIATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; FEMALE; GOAT; HEART ATRIUM FIBRILLATION; HEART DEVELOPMENT; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ATRIAL FIBRILLATION; BIOLOGICAL MARKERS; CARDIAC PACING, ARTIFICIAL; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL NUCLEUS; CHRONIC DISEASE; CONTRACTILE PROTEINS; CYTOSKELETAL PROTEINS; FEMALE; GOATS; HEART ATRIA; IMMUNOHISTOCHEMISTRY; MUSCLE PROTEINS; MUSCLE, SMOOTH; MYOCARDIUM; PROTEIN KINASES; SARCOPLASMIC RETICULUM;

EID: 0030770732     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (77)

1. White CW, Kerber RE, Weiss HR, Marcus ML: The effects of atrial fibrillation on atrial pressure-volume and flow relationships. Circ Res 1982, 51:205-215
2. Borgers M, Ausma J, Wijffels M, Allessie M: Atrial fibrillation in the goat: a model for chronic hibernating myocardium. Circulation 1994, 90:1-407
3. Ausma J, Wijffels M, Thoné F, Wouters L, Allessie M, Borgers M: Structural changes of atrial myocardium after chronic atrial fibrillation in the goat. Circulation 1997 (in press)
4. Ausma J, Borgers M, Wijffels M, Ramaekers F, Allessie M: Chronic atrial fibrillation induces changes in cardiomyocyte phenotype. J Mol Cell Cardiol 1996, 28:A80
5. Borgers M, Thoné F, Wouters L, Ausma J, Shivalkar B, Flameng W: Structural correlates of regional myocardial dysfunction in patients with critically coronary artery stenosis: chronic hibernation? Cardiovasc Pathol 1993, 2:237-245
6. Rahimtoola SH: A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation 1985, 72:V123-V135
7. Vanoverschelde JLJ, Wijns W, Depré C, Essamri B, Heyndricks S, Borgers M, Bol A, Melin J: Mechanisms of chronic regional postischemic dysfunction in humans: new insights from the study on non-infarcted collateral dependent myocardium. Circulation 1993, 87: 1513-1523
8. Ausma J, Schaart G, Thoné F, Shivalkar B, Flameng W, Depré C, Vanoverschelde J-L, Ramaekers F, Borgers M: Chronic ischemic viable myocardium in man: aspects of dedifferentiation. Cardiovasc Pathol 1995, 4:29-37
9. Ausma J, Fürst D, Thoné F, Shivalkar B, Flameng W, Weber K, Ramaekers F, Borgers M: Molecular changes of titin in left ventricular dysfunction as a result of chronic hibernation. J Mol Cell Cardiol 1995, 27:1203-1212
10. Ausma J, Van Eys GJJM, Broers JLV, Thone F, Flameng W, Ramaekers FCS, Borgers M: Nuclear lamin expression in chronic hibernating myocardium in man. J Mol Cell Cardiol 1996, 28:1297-1305
11. Danto BI, Fischman DA: Immunocytochemical analysis of intermediate filaments in embryonic heart cells with monoclonals to desmin. J Cell Biol 1984, 98:2179-2191
12. Tokuyasu KT, Maher PA: Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. I. Presence of immunofluorescent titin spots in premyofibril stages. J Cell Biol 1987, 105:2781-2793
13. Tokuyasu KT, Maher PA: Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. II. Generation of α-actinin dots within titin spots at the time of the first myofibril formation. J Cell Biol 1987, 105:2795-2801
14. Schaart G, Viebahn C, Langmann W, Ramaekers FCS: Desmin and titin expression in early postimplantation mouse embryos. Development 1989, 107:585-596
15. Van der Loop FTL, Schaart G, Langmann W, Ramaekers FCS, Viebahn CH: Expression and organisation of muscle specific proteins during early development stages of the rabbit heart. Anat Embryol 1992, 185:439-450
16. Schaart G, Moens L, Endert J, Ramaekers FCS: Biochemical characterization of cardiotin, a sarcoplasmic reticulum associated protein. FEBS Lett 1997, 403:168-172
17. Schaart G, Van der Ven PMF, Ramaekers FCS: Characterization of cardiotin, a structural component in the myocardium. Eur J Cell Biol 1993, 62:34-48
18. Wijffels MCEF, Kirchhof CJHJ, Dorland R, Allessie MA: Atrial fibrillation begets atrial fibrillation: a study in awake chronically instrumented goats. Circulation 1995, 92:1954-1968
19. Flameng W, Wouters L, Sergeant P, Lewi P, Borgers M, Thoné F, Suy R: Multivariate analysis of angiographic histologic and electrocardiographic data in patients with coronary heart disease. Circulation 1984, 70:7-17
20. Junqueria LCU, Bignolas G, Bretani RR: Picrosirius staining plus polarization microscopy: a specific method for collagen detection in tissue sections. Histochem J 1979, 11:447-455
21. MacKenna DA, Omens JH, McCulloch AD, Covell JW: Contribution of collagen matrix to passive left ventricular mechanisms in isolated rat hearts. Am J Physiol 1994, 266:H1007-H1018
22. Shapiro EP, Effron MB, Lima S, Ouyang P, Siu CO, Bush D: Transient atrial dysfunction after conversion of chronic atrial fibrillation to sinus rhythm. Am J Cardiol 1988, 62:1202-1207
23. Manning W, Silverman D, Katz S, Riley M, Came P, Doherty R, Munson J, Douglas P: Impaired left atrial mechanical function after cardioversion: relation to the duration of atrial fibrillation. J Am Coll Cardiol 1994, 23:135-140
24. Woodcock-Mitchell J, Mitchell JJ, Low RB, Kieny M, Sengel P, Rubbia L, Skalli O, Jackson B, Gabbiani G: α-Smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. Differentiation 1988, 39:161-166
25. Babai F, Musir-Aghdam J, Schurch W, Royal A, Gabbiani G: Coexpression of α-sarcomeric, α-smooth muscle actin and desmin during myogenesis in rat and mouse embryos. I. Skeletal muscle. Differentiation 1990, 44:132-142
26. Bochaton-Piallat M-L, Ropraz P, Gabbiani G, Santeusanio G, Palmieri G, Schiaroli S, Spagnoli LG: Actin isoform and intermediate filament protein expression in human developing skeletal muscle. BAM 1992, 2:83-87
27. Wang S-M, Greaser ML, Schultz E, Bulinski JC, Lin JJC, Lessard JL: Studies on cardiac myofibrillogenesis with antibodies to titin, actin, tropomyosin and myosin. J Cell Biol 1988, 107:1075-1083
28. Van der Loop FTL, Van der Ven PMF, Fürst DO, Gautel M, Van Eys GJJM, Ramaekers FCS: Integration of titin in the sarcomeres of cultured differentiating human skeletal muscle cells. Eur J Cell Biol 1996, 69:301-307
29. Van der Loop FTL, Van Eys GJJM, Schaart G, Ramaekers FCS: Titin expression as an early marker of heart and skeletal muscle differentiation in vitro: developmental re-organisation in relation to cytoskeletal constituents. J Muscle Res Cell Motil 1996, 17:23-36
30. Schultheiss T, Lin Z, Lu M-H, Murray J, Fischman DA, Weber K, Masaki T, Imamura M, Holtzer H: Differential distribution of subsets of myofibrillar proteins in cardiac non-striated and striated myofibrils. J Cell Biol 1990, 110:1159-1172
31. Van der Ven PMF, Schaart G, Jap PHK, Sengers RCA, Stadhouders AM, Ramaekers FCS: Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation. Cell Tissue Res 1992, 270:189-198
32. Van der Ven PMF, Schaart G, Croes HJE, Jap PHK, Ginsel LA, Ramaekers FCS: Titin aggregates associated with intermediate filaments align along stress fiber-like structures during human skeletal muscle cell differentiation. J Cell Sci 1993, 106:749-759
33. Cary RB, Klymkowsky MW: Disruption of intermediate filament organization leads to structural defects at the intersomite junction in Xenopus myotomal muscle. Development 1995, 121:1041-1052
34. Van der Loop FTL, Schaart G, Langmann H, Ramaekers FCS, Viebahn Ch: Rearrangement of intercellular junctions and cytoskeletal proteins during rabbit myocardium development. Eur J Cell Biol 1995, 68:62-69
35. Leistadt E, Aksnes G, Verburg E, Christensen G: Atrial contractile dysfunction after short-term atrial fibrillation is reduced by verapamil but increased by BAY K8644. Circulation 1996, 93:1747-1754
36. Thompson EW, Marino TA, Uboh CE, Kent RL, Cooper G: Atrophy reversal and cardiomyocyte redifferentiation in reloaded cat myocardium. Circ Res 1984, 367-377
37. Sharp WW, Terracio L, Borg TK, Samarel AM: Contractile activity modulates actin synthesis and turnover in cultured neonatal rat heart cells. Circ Res 1993, 73:172-183
38. Manning W, Silverman D, Katz S, Riley M, Came P, Doherty R, Munson J, Douglas P: Impaired left atrial mechanical function after cardioversion: relation to the duration of atrial fibrillation. J Am Coll Cardiol 1994, 23:135-140
39. Simpson DG, Carver W, Borg TK, Terracio L: Role of mechanical stimulation in the establishment and maintenance of muscle cell differentiation. Int Rev Cytol 1994, 150:69-94
40. Ausma J, Cleutjens JPM, Thoné F, Flameng W, Ramaekers F, Borgers M: Chronic hibernating myocardium: interstitial changes. Mol Cel Biochem 1995, 147:35-42
41. Fisher SA, Periasamy M: Collagen synthesis inhibitors disrupt embryonic cardiomyocyte myofibrillogenesis and alter the expression of cardiac specific genes in vitro. J Mol Cell Cardiol 1994, 26:721-731
42. Borisov AB: Myofibrillogenesis and reversible disassembly of myofibrils as adaptive reactions of cardiac muscle cells. Acta Physiol Scand 1991, S599:71-80
43. Mary-Rabine L, Albert A, Pham TD, Hordorf, Fenoglio JJ, Malm JR, Rosen MR: The relationship of human atrial cellular electrophysiology to clinical function and ultrastructure. Circ Res 1983, 52:188-199
44. Greaser ML, Handel SE, Wang SM, Schultz E, Bulinski JC, Lessard JL: Assembly of titin, myosin, actin and tropomyosin into myofibrils in cultured chick cardiomyocytes. UCLA Symp Mol Cell Biol 1989, 93:246-257
45. Wang S-M, Greaser ML: Immunocytochemical studies using a monoclonal antibody to bovine cardiac titin on intact and extracted myofibrils. J Muscle Res Cell Motil 1985, 6:293-312
46. Fürst DO, Osborn M, Nave R, Weber K: The organisation of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol 1988, 106:1563-1572
47. Fürst DO, Nave R, Osborn M, Weber K: Repetitive titin epitopes with a 42 nm spacing coincide in relative position with known A band striations also identified by major myosin-associated proteins: an immunoelectron-microscopical study on myofibrils. J Cell Sci 1989, 94:119-125
48. Obermann WHJ, Gautel M, Steiner F, Van der Ven PMF, Weber K, Fürst DO: The structure of the sarcomeric M-band: localization of defined domains of myomesin, M-protein and the 250 kD carboxyterminal region of titin by immunoelectron microscopy. J Cell Biol 1996, 134:1441-1453
49. Vinkemeier U, Obermann W, Weber K, Fürst DO: The globular head domain of titin extends into the center of the sarcomeric M band: cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins. J Cell Sci 1993, 106:319-330
50. Gautel M, Zuffardi O, Freiburg A, Labeit S: Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction. EMBO J 1995, 14:1952-1960
51. Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillesen D, Gabbiani G: A monoclonal antibody against α-smooth muscle: a new probe for smooth muscle differentiation. J Cell Biol 1986, 103:2787-2796
52. 2+-ATPaSe of cardiac sarcoplasmic reticulum cross-reacts with slow type I but not with fast type II canine skeletal muscle fibers: an immunocytochemical and immunochemical study. Cell Motil Cytoskel 1988, 9:164-174
53. 2+-pump isoforms and of phospholamban in pig smooth muscle tissues. Biochem J 1990, 271:649-653
54. 2+-transport ATPase. Biochem J 1989, 264:765-769
55. 2+ pump is expressed in platelets, in lymphoid cells, and in mast cells. J Biol Chem 1994, 269:1410-1416
56. Kobayashi M, Ohtsuka K, Tamura K, Ohara K, Fujihira S, Hirano Y, Kusunoki C, Hayashi M, Satoh S, Katayama M: Production of monoclonal antibody against recombinant human FKBP-12 and subcellular localization of FKBP-12 in human mononuclear and polymorphonuclear cells. Transplant Proc 1993, 25:655-657
57. Knudson CM, Chaudhari N, Sharp AH, Powell JA, Beam KG, Campbell KP: Specific absence of the α1 subunit of the dihydropyridine receptor in mice with muscular dysgenesis. J Biol Chem 1989, 264: 1345-1348
58. Suzuki T, Lui P, Wang JH: Rapid purification of phospholamban by monoclonal antibody immunoaffinity chromatography. Biochem Cell Biol 1987, 65:302-309
59. Bader D, Masaki T, Fischman DA: Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol 1982, 95:763-770
60. Das KM, Dasgupta A, Mandal A, Geng X: Autoimmunity of cytoskeletal protein tropomyosin: a clue to the pathogenetic mechanism for ulcerative colitis. J Immunol 1993, 150:2487-2493
61. Debus E, Weber K, Osborn M: Monoclonal antibodies to desmin, the muscle specific intermediate filament. EMBO J 1983, 2:2305-2312
62. Pieper FR, Schaart G, Krimpenfort PJ, Hendrik JB, Moshage HJ, Ramaekers FCS, Berns A, Bloemendal H: Transgenic expression of the expression of the muscle specific intermediate filament protein desmin in non-muscle cells. J Cell Biol 1989, 108:1009-1024
63. Ramaekers FCS, Moesker O, Huysmans A, Schaart G, Westerhof G, Wagenaar SS, Herman CJ, Vooijs GP: Intermediate filament proteins in the study of tumor heterogeneity: an in-depth study on tumors of the urinary and respiratory tracts. Ann NY Acad Sci 1985, 455:614-634
64. Ramaekers FCS, Huysmans A, Schaart G, Moesker O, Vooijs GP: Tissue distribution of keratin 7 as monitored by a monoclonal antibody. Exp Cell Res 1987, 170:235-249
65. Smedts F, Ramaekers F, Robben H, Pruszczynski M, Van Muijen G, Lane B, Leigh I, Vooijs P: Changing patterns of keratin expression during progression of cervical intra-epithelial neoplasia. Am J Pathol 1990, 136:657-668
66. Van Helden WCH, Kok-Verspuy A, Harff GA, van Kamp GJ: Ratenephelometric determination of fibronectin in plasma. Clin Chem 1985, 31:1182-1184
67. Verstraeten AA, Mackie EJ, Hageman PC, Hilgers J, Schol DJ, De Jongh GJ, Schalkwijk J: Tenascin expression in basal cell carcinoma. Br J Dermatol 1992, 127:571-574
68. Garbarsch C, Matthiessen ME, Olsen BE, Moe D, Kirkeby S: Immunohistochemistry of the intracellular matrix components and the epithelio-mesenchymal junction of the human tooth germ. Histochem J 1994, 26:110-118
69. Fleming TP, Garrod DR, Elsmore AJ: Desmosome biogenesis in the mouse preimplantation embryo. Development 1991, 112:527-539
70. Parrish EP, Steart PV, Garrod DR, Weller R: Antidesmosomal monoclonal antibody in the diagnosis of intracranial tumors. J Pathol 1987, 153:265-273
71. Koch PJ, Walsch MJ, Schmelz M, Goldschmidt MD, Zimblemann R, Franke WW: Identification of desmoglein, a constitutive desmosomal glycoprotein as a member of the cadherin family of cell adhesion molecules. Eur J Cell Biol 1990, 53:1-12
72. Gourdie RG, Severs NJ, Green CR, Rothery S, Germroth S, Thompson RP: The spatial distribution and relative abundance of gap-junctional connexin 40 and 43 correlated to functional properties of components of cardiac atrioventricular conduction system. J Cell Sci 1993, 105:985-991
73. Geiger B, Volberg T, Ginsberg D, Bitzur S, Sabanay I, Hynes RO: Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin. J Cell Sci 1990, 97:607-614
74. Hozák P, Sasseville M-J, Raymond Y, Cook PR: Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J Cell Sci 1995, 108:635-644
75. Machiels BM, Broers JLV, Raymond Y, De Ley L, Kuijpers HJH, Caberg NEH, Ramaekers FCS: Abnormal A-type lamin organization in human lung carcinoma cell lines. Eur J Cell Biol 1995, 67:328-335
76. Zatloukal K, Denk H, Spurej G, Hutter H: Modulation of protein composition of nuclear lamina-reduction of lamins-B1 and lamins-B2 in livers of griseofulvin-treated mice. Lab Invest 1992, 66:589-597
77. Bridger JM, Kill I, O'Farrell M, Hutchison CJ: Internal lamin substructure within G1 nuclei of human dermal fibroblasts. J Cell Sci 1993, 104:297-306