Multiple malformation syndrome following fluconazole use in pregnancy: Report of an additional patient

American Journal of Medical Genetics

Volumn 72, Issue 3, 1997, Pages 253-256

  Aleck, Kyrieckos A ^a,c   Bartley, Douglas L ^b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b MARICOPA MEDICAL CENTER   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Antley Bixler syndrome; Fluconazole; Radiohumeral synostosis; Teratogenesis

Indexed keywords

FLUCONAZOLE;

ARTICLE; CASE REPORT; EAR MALFORMATION; EXOPHTHALMOS; HUMAN; MALE; MULTIPLE MALFORMATION SYNDROME; NEWBORN; NOSE MALFORMATION; PRENATAL EXPOSURE; PRIORITY JOURNAL; SYNOSTOSIS; TERATOGENESIS; TERATOGENICITY;

ABNORMALITIES, MULTIPLE; ADULT; AMPHOTERICIN B; ANTIFUNGAL AGENTS; COCCIDIOIDES; COCCIDIOIDOMYCOSIS; FEMALE; FLUCONAZOLE; HUMANS; INFANT, NEWBORN; MALE; MENINGITIS, FUNGAL; OSTEOCHONDRODYSPLASIAS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

PYRUS COMMUNIS;

EID: 0030770714     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19971031)72:3<253::AID-AJMG1>3.0.CO;2-S     Document Type: Article

References (12)

1. Buttar HS, Moffatt JH, Bura C (1991): Pregnancy outcome in ketoconazole-treated rats and mice [abstract no. P117]. Teratology 43:424.
2. Como JA, Dismukes WE (1994): Oral azol drugs as sysemic antifungal therapy. N Engl J Med 330:263-272.
3. Galgiani JN, Cantanzaro A, Cloud GA, Higgs J, Friedman BA, Larsen RA, Graybill JR, and the NIAID-Mycoses Study Group (1993): Fluconazole therapy for coccidioidal meningitis. Ann Intern Med 119:28-35.
4. Hassel S, Butler MG (1994): Antley-Bixler syndrome: Report of a patient and review of the literature. Clin Genet 46:372-376.
5. Inman W, Pearce G, Wilton L (1994): Safety of fluconazole in the treatment of vaginal candidiasis: A prescription-event monitoring study, with special reference to the outcome of pregnancy. Eur J Clin Pharmacol 46: 115-118.
6. Lee BE, Feinberg M, Abraham JJ, Murthy ARK (1992): Congenital malformations in an infant born to a woman treated with fluconazole. Pediatr Infect Dis J 11:1062-1064.
7. Lind J (1985): Limb malformations in a case of hydrops fetalis with ketoconazole use during pregnancy. Arch Gynecol 237:398.
8. Pursley TJ, Blomquist IK, Abraham J, Andersen HF, Bartley, JA (1996): Fluconazole-induced congenital anomalies in three infants. Clinical Infect Dis 22:336-340.
9. Saag MS, Dismukes WE (1988): Azole antifungal agents: Emphasis on new triazoles. Antimicrob Agents Chemother 32:1-8.
10. Tachibana M, Noguchi Y, Monro AM (1987): Toxicology of fluconizole in experimental animals. In: Fromptling RA (ed): "Recent Trends in the Discovery, Development and Evaluation of Fungal Drugs." Barcelona, Spain: JR Prous.
11. Tiboni GM (1993): Second branchial arch anomalies induced by fluconazole, a bis-triazole antifungal agent, in cultured mouse embryos. Chem Pathol Pharrnacol 79:381-384.
12. Van Cauteren H, Coussement W, Vandenberghe J, Herin V, Vanparys P, Marsboom R (1987): The lexicological properties of itraconazole. In Fromtling RA (ed): "Recent Trends in the Discovery, Development and Evaluation of Antifungal Agents." Barcelona, Spain: J.R. Prous.