메뉴 건너뛰기




Volumn 54, Issue 2, 1997, Pages 170-179

How HLA-DM affects the peptide repertoire bound to HLA-DR molecules

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; DIMER; HLA DM ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE; UNCLASSIFIED DRUG;

EID: 0030770701     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(97)00077-3     Document Type: Review
Times cited : (28)

References (69)
  • 1
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain RN: MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 76:287, 1994.
    • (1994) Cell , vol.76 , pp. 287
    • Germain, R.N.1
  • 2
    • 0026088251 scopus 로고
    • Formation of a nine-subunit complex by HLa class II glycoproteins and the invariant chain
    • Roche PA, Marks MS, Cresswell P: Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain. Nature 354:392, 1991.
    • (1991) Nature , vol.354 , pp. 392
    • Roche, P.A.1    Marks, M.S.2    Cresswell, P.3
  • 3
    • 0025202076 scopus 로고
    • MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
    • Bakke O, Dobberstein B: MHC class II-associated invariant chain contains a sorting signal for endosomal compartments. Cell 63:707, 1990.
    • (1990) Cell , vol.63 , pp. 707
    • Bakke, O.1    Dobberstein, B.2
  • 5
    • 0026353496 scopus 로고
    • Proteolysis of the MHC class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules
    • Roche PA, Cresswell P: Proteolysis of the MHC class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc Natl Acad Sci USA 88:3150, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3150
    • Roche, P.A.1    Cresswell, P.2
  • 6
    • 0028344898 scopus 로고
    • Endosomal aspartic proteinases are required for invariant chain processing
    • Marie MA, Taylor MD, Blum JS: Endosomal aspartic proteinases are required for invariant chain processing. Proc Natl Acad Sci USA 91:2171, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2171
    • Marie, M.A.1    Taylor, M.D.2    Blum, J.S.3
  • 7
    • 0026440236 scopus 로고
    • HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
    • Riberdy JM, Newcomb JR, Surman MJ, Barbosa JA, Cresswell P: HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 360:474, 1992.
    • (1992) Nature , vol.360 , pp. 474
    • Riberdy, J.M.1    Newcomb, J.R.2    Surman, M.J.3    Barbosa, J.A.4    Cresswell, P.5
  • 8
    • 0028136262 scopus 로고
    • The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy
    • Romagnoli P, Germain RN: The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy. J Exp Med 180:1107, 1994.
    • (1994) J Exp Med , vol.180 , pp. 1107
    • Romagnoli, P.1    Germain, R.N.2
  • 9
    • 0027489002 scopus 로고
    • The segment of invariant chain that is critical for association with MHC class II molecules contains the sequence of a peptide eluted from class II polypeptides
    • Freisewinkel IM, Schenck K, Koch N: The segment of invariant chain that is critical for association with MHC class II molecules contains the sequence of a peptide eluted from class II polypeptides. Proc Natl Acad Sci USA 90:9703, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9703
    • Freisewinkel, I.M.1    Schenck, K.2    Koch, N.3
  • 10
    • 0028867141 scopus 로고
    • Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR
    • Vogt AB, Stern LJ, Amshoff C, Dobberstein B, Hämmerling GJ, Kropshofer H: Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR. J Immunol 155:4757, 1995.
    • (1995) J Immunol , vol.155 , pp. 4757
    • Vogt, A.B.1    Stern, L.J.2    Amshoff, C.3    Dobberstein, B.4    Hämmerling, G.J.5    Kropshofer, H.6
  • 11
    • 0025331726 scopus 로고
    • Invariant chain association with HLA-DR molecules inhibits immunogeneic peptide binding
    • Roche PA, Cresswell P: Invariant chain association with HLA-DR molecules inhibits immunogeneic peptide binding. Nature 345:615, 1990.
    • (1990) Nature , vol.345 , pp. 615
    • Roche, P.A.1    Cresswell, P.2
  • 12
    • 0021167161 scopus 로고
    • Homozygous deletions that simultaneously eliminate expression of class I and class II antigens of EBV-transformed B-lymphoblastoid cells: Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens
    • DeMars R, Chang CC, Shaw S, Reitnauer PJ, Sondel PM: Homozygous deletions that simultaneously eliminate expression of class I and class II antigens of EBV-transformed B-lymphoblastoid cells: reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens. Hum Immunol 11:77, 1984.
    • (1984) Hum Immunol , vol.11 , pp. 77
    • DeMars, R.1    Chang, C.C.2    Shaw, S.3    Reitnauer, P.J.4    Sondel, P.M.5
  • 13
    • 0022625982 scopus 로고
    • Molecular analysis of HLa class I and class II antigen loss mutants reveals a homozygous deletion of the DR, DQ and part of the DP regions: Implications for class II gene order
    • Ehrlich H, Lee JS, Petersen JW, Bugawan T, DeMars R: Molecular analysis of HLA class I and class II antigen loss mutants reveals a homozygous deletion of the DR, DQ and part of the DP regions: implications for class II gene order. Hum Immunol 16:205, 1986.
    • (1986) Hum Immunol , vol.16 , pp. 205
    • Ehrlich, H.1    Lee, J.S.2    Petersen, J.W.3    Bugawan, T.4    DeMars, R.5
  • 14
    • 0025056497 scopus 로고
    • Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes
    • Mellins E, Smith L, Arp B, Cotner T, Celis E, Pious D: Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes. Nature 343:71, 1990.
    • (1990) Nature , vol.343 , pp. 71
    • Mellins, E.1    Smith, L.2    Arp, B.3    Cotner, T.4    Celis, E.5    Pious, D.6
  • 15
    • 0026566332 scopus 로고
    • The antigen processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation
    • Riberdy JM, Cresswell P: The antigen processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation. J Immunol 148:2586, 1992.
    • (1992) J Immunol , vol.148 , pp. 2586
    • Riberdy, J.M.1    Cresswell, P.2
  • 17
    • 0028676010 scopus 로고
    • In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides
    • Avva R, Cresswell P: In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides. Immunity 1:763, 1994.
    • (1994) Immunity , vol.1 , pp. 763
    • Avva, R.1    Cresswell, P.2
  • 18
  • 20
    • 0028217255 scopus 로고
    • The HLA-DMA gene is required for the formation of stable class II/peptide complexes
    • Fling SP, Arp B, Pious D: The HLA-DMA gene is required for the formation of stable class II/peptide complexes. Nature 368:554, 1994.
    • (1994) Nature , vol.368 , pp. 554
    • Fling, S.P.1    Arp, B.2    Pious, D.3
  • 22
    • 0025940456 scopus 로고
    • New class II-like genes in the murine MHC
    • Cho S, Attaya M, Monaco JJ: New class II-like genes in the murine MHC. Nature 353:573, 1991.
    • (1991) Nature , vol.353 , pp. 573
    • Cho, S.1    Attaya, M.2    Monaco, J.J.3
  • 24
    • 0028366547 scopus 로고
    • Limited polymorphism in HLA-DM does not involve the peptide binding groove
    • Sanderson F, Powis SH, Kelly AP, Trowsdale J: Limited polymorphism in HLA-DM does not involve the peptide binding groove. Immunogenetics 39:56, 1994.
    • (1994) Immunogenetics , vol.39 , pp. 56
    • Sanderson, F.1    Powis, S.H.2    Kelly, A.P.3    Trowsdale, J.4
  • 25
    • 0029426741 scopus 로고
    • Kissing cousins exchange CLIP
    • Sanderson F, Trowsdale J: Kissing cousins exchange CLIP. Curr Biol 5:1372, 1995.
    • (1995) Curr Biol , vol.5 , pp. 1372
    • Sanderson, F.1    Trowsdale, J.2
  • 26
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin LK, Cresswell P: HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82:155, 1995.
    • (1995) Cell , vol.82 , pp. 155
    • Denzin, L.K.1    Cresswell, P.2
  • 27
    • 0030978530 scopus 로고    scopus 로고
    • HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH
    • Kropshofer H, Arndt SO, Moldenhauer G, Hämmerling GJ, Vogt AB: HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH. Immunity 6:293, 1997.
    • (1997) Immunity , vol.6 , pp. 293
    • Kropshofer, H.1    Arndt, S.O.2    Moldenhauer, G.3    Hämmerling, G.J.4    Vogt, A.B.5
  • 29
    • 0028820625 scopus 로고
    • A lysosomal targeting signal in the cytoplasmic tail of the β chain directs HLA-DM to MHC class II compartments
    • Marks MS, Roche PA, van Donselaar E, Woodruff L, Peters PJ, Bonifacino JS: A lysosomal targeting signal in the cytoplasmic tail of the β chain directs HLA-DM to MHC class II compartments. J Cell Biol 131:351, 1995.
    • (1995) J Cell Biol , vol.131 , pp. 351
    • Marks, M.S.1    Roche, P.A.2    Van Donselaar, E.3    Woodruff, L.4    Peters, P.J.5    Bonifacino, J.S.6
  • 30
    • 0028789975 scopus 로고
    • The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
    • Lindstedt R, Liljedahl M, Péléraux A, Peterson PA, Karlsson L: The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity 3:561, 1995.
    • (1995) Immunity , vol.3 , pp. 561
    • Lindstedt, R.1    Liljedahl, M.2    Péléraux, A.3    Peterson, P.A.4    Karlsson, L.5
  • 31
    • 0028618339 scopus 로고
    • Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells
    • Karlsson L, Péléraux A, Lindstedt R, Liljedahl M, Peterson PA: Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells. Science 266: 1569, 1994.
    • (1994) Science , vol.266 , pp. 1569
    • Karlsson, L.1    Péléraux, A.2    Lindstedt, R.3    Liljedahl, M.4    Peterson, P.A.5
  • 33
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptides
    • Sherman MA, Weber DA, Jensen P: DM enhances peptide binding to class II MHC by release of invariant chain-derived peptides. Immunity 3:197, 1995.
    • (1995) Immunity , vol.3 , pp. 197
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.3
  • 34
    • 0028047736 scopus 로고
    • A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides
    • Mellins E, Cameron P, Amaya M, Goodman S, Pious D, Smith L, Arp B: A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides. J Exp Med 179:541, 1994.
    • (1994) J Exp Med , vol.179 , pp. 541
    • Mellins, E.1    Cameron, P.2    Amaya, M.3    Goodman, S.4    Pious, D.5    Smith, L.6    Arp, B.7
  • 36
    • 0030458137 scopus 로고    scopus 로고
    • HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules
    • Denzin LK, Hammond C, Cresswell P: HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J Exp Med 184:2153, 1996.
    • (1996) J Exp Med , vol.184 , pp. 2153
    • Denzin, L.K.1    Hammond, C.2    Cresswell, P.3
  • 37
    • 0030589330 scopus 로고    scopus 로고
    • HLA-DM is present in one-fifth the amount of HLA-DR in the class II peptide loading compartment where it associates with leupeptin-induced peptide (LIP)-HLA-DR complexes
    • Schafer PH, Green JM, Malapati S, Gu L, Pierce SK: HLA-DM is present in one-fifth the amount of HLA-DR in the class II peptide loading compartment where it associates with leupeptin-induced peptide (LIP)-HLA-DR complexes. J Immunol 157:5487, 1996.
    • (1996) J Immunol , vol.157 , pp. 5487
    • Schafer, P.H.1    Green, J.M.2    Malapati, S.3    Gu, L.4    Pierce, S.K.5
  • 39
    • 0024393778 scopus 로고
    • Peptide binding and release by proteins implicated as catalysts of protein assembly
    • Flynn GC, Chappell TG, Rothman JE: Peptide binding and release by proteins implicated as catalysts of protein assembly. Science 245:385, 1989.
    • (1989) Science , vol.245 , pp. 385
    • Flynn, G.C.1    Chappell, T.G.2    Rothman, J.E.3
  • 41
    • 0028789889 scopus 로고
    • HLA-DM: An in vivo facilitator of MHC class II peptide loading
    • Roche PA: HLA-DM: an in vivo facilitator of MHC class II peptide loading. Immunity 3:259, 1995.
    • (1995) Immunity , vol.3 , pp. 259
    • Roche, P.A.1
  • 42
    • 0028921633 scopus 로고
    • Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II
    • Sette A, Southwood S, Miller J, Appella E: Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II. J Exp Med 181:677, 1995.
    • (1995) J Exp Med , vol.181 , pp. 677
    • Sette, A.1    Southwood, S.2    Miller, J.3    Appella, E.4
  • 43
    • 0029824101 scopus 로고    scopus 로고
    • Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM
    • Weber DA, Evavold BD, Jensen PE: Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science 274:618, 1996.
    • (1996) Science , vol.274 , pp. 618
    • Weber, D.A.1    Evavold, B.D.2    Jensen, P.E.3
  • 48
    • 0029807634 scopus 로고    scopus 로고
    • Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs
    • van Ham SM, Grüneberg U, Malcharek G, Bröker I, Melms A, Trowsdale J: Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs. J Exp Med 184:2019, 1996.
    • (1996) J Exp Med , vol.184 , pp. 2019
    • Ham, S.M.1    Grüneberg, U.2    Malcharek, G.3    Bröker, I.4    Melms, A.5    Trowsdale, J.6
  • 51
    • 0029853195 scopus 로고    scopus 로고
    • Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules
    • Katz JF, Stebbins C, Appella E, Sant AJ: Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules. J Exp Med 184:1747, 1996.
    • (1996) J Exp Med , vol.184 , pp. 1747
    • Katz, J.F.1    Stebbins, C.2    Appella, E.3    Sant, A.J.4
  • 52
    • 0031080953 scopus 로고    scopus 로고
    • How HLA-DM edits the MHC class II peptide repertoire: Survival of the fittest?
    • Kropshofer H, Hämmerling GJ, Vogt AB: How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest? Immunol Today 18:77, 1997.
    • (1997) Immunol Today , vol.18 , pp. 77
    • Kropshofer, H.1    Hämmerling, G.J.2    Vogt, A.B.3
  • 53
    • 0030068236 scopus 로고    scopus 로고
    • A structural transition in class II major histocompatibility complex proteins at mildly acidic pH
    • Runnels HA, Moore JC, Jensen PE: A structural transition in class II major histocompatibility complex proteins at mildly acidic pH. J Exp Med 183:127, 1996.
    • (1996) J Exp Med , vol.183 , pp. 127
    • Runnels, H.A.1    Moore, J.C.2    Jensen, P.E.3
  • 54
    • 0030030896 scopus 로고    scopus 로고
    • Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced
    • Boniface JJ, Lyons DS, Wettstein DA, Allbritton NL, Davis MM: Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced. J Exp Med 183:119, 1996.
    • (1996) J Exp Med , vol.183 , pp. 119
    • Boniface, J.J.1    Lyons, D.S.2    Wettstein, D.A.3    Allbritton, N.L.4    Davis, M.M.5
  • 55
    • 0029121404 scopus 로고
    • Differential stability of HLA-DR alleles independent of endogenous peptides
    • Devaux B, Wilson KJ, Aguilar B, Jorgensen B, Rothbard JB: Differential stability of HLA-DR alleles independent of endogenous peptides. J Immunol 155:1921, 1995.
    • (1995) J Immunol , vol.155 , pp. 1921
    • Devaux, B.1    Wilson, K.J.2    Aguilar, B.3    Jorgensen, B.4    Rothbard, J.B.5
  • 56
    • 0025826118 scopus 로고
    • MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
    • Germain R, Hendrix LR: MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353:134, 1991.
    • (1991) Nature , vol.353 , pp. 134
    • Germain, R.1    Hendrix, L.R.2
  • 57
    • 0025870669 scopus 로고
    • A role for peptide in determining MHC class II structure
    • Sadegh-Nasseri S, Germain RN: A role for peptide in determining MHC class II structure. Nature 353:167, 1991.
    • (1991) Nature , vol.353 , pp. 167
    • Sadegh-Nasseri, S.1    Germain, R.N.2
  • 58
    • 0026571278 scopus 로고
    • The human MHC class II protein HLA-DR1 assembles as empty αβ-heterodimers in the absence of antigenic peptide
    • Stern LJ, Wiley DC: The human MHC class II protein HLA-DR1 assembles as empty αβ-heterodimers in the absence of antigenic peptide. Cell 68:465, 1992.
    • (1992) Cell , vol.68 , pp. 465
    • Stern, L.J.1    Wiley, D.C.2
  • 59
    • 0027303736 scopus 로고
    • Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules
    • Germain R, Rinker AG Jr: Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes selective cell surface expression of occupied molecules. Nature 363:725, 1993.
    • (1993) Nature , vol.363 , pp. 725
    • Germain, R.1    Rinker A.G. Jr2
  • 60
    • 0024314918 scopus 로고
    • Molecular chaperones: Proteins essential for the biogenesis of some macromolecular structures
    • Ellis RJ, Hemmingsen SM: Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures. Trends Biochem Sci 14:339, 1989.
    • (1989) Trends Biochem Sci , vol.14 , pp. 339
    • Ellis, R.J.1    Hemmingsen, S.M.2
  • 61
    • 0028135019 scopus 로고
    • Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA-DM genes
    • Brooks AG, Campbell PL, Reynolds P, Gautam AM, McCluskey J: Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA-DM genes. J Immunol 153: 5382, 1994.
    • (1994) J Immunol , vol.153 , pp. 5382
    • Brooks, A.G.1    Campbell, P.L.2    Reynolds, P.3    Gautam, A.M.4    McCluskey, J.5
  • 62
    • 0028899617 scopus 로고
    • The requirement for DM in class II restricted antigen presentation and SDS-stable dimer formation is allele and species dependent
    • Stebbins CS, Loss GE Jr, Elias CG, Chervonsky A, Sant AJ: The requirement for DM in class II restricted antigen presentation and SDS-stable dimer formation is allele and species dependent. J Exp Med 181:223, 1995.
    • (1995) J Exp Med , vol.181 , pp. 223
    • Stebbins, C.S.1    Loss G.E., Jr.2    Elias, C.G.3    Chervonsky, A.4    Sant, A.J.5
  • 63
    • 0030636722 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of antigens overcomes the requirement for HLA-DM in class II-restricted antigen presentation
    • Ma C, Blum JS: Receptor-mediated endocytosis of antigens overcomes the requirement for HLA-DM in class II-restricted antigen presentation. J Immunol 158:1, 1997.
    • (1997) J Immunol , vol.158 , pp. 1
    • Ma, C.1    Blum, J.S.2
  • 64
    • 0028240914 scopus 로고
    • Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH
    • Urban RG, Chicz RM, Strominger JL: Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH. J Exp Med 180:751, 1994.
    • (1994) J Exp Med , vol.180 , pp. 751
    • Urban, R.G.1    Chicz, R.M.2    Strominger, J.L.3
  • 65
    • 0029114962 scopus 로고
    • Structural features of invariant chain CLIP region controlling rapid release from HLA-DR molecules and inhibition of peptide binding
    • Kropshofer H, Vogt AB, Hämmerling GJ: Structural features of invariant chain CLIP region controlling rapid release from HLA-DR molecules and inhibition of peptide binding. Proc Natl Acad Sci USA 92:8313, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8313
    • Kropshofer, H.1    Vogt, A.B.2    Hämmerling, G.J.3
  • 66
    • 0029014498 scopus 로고
    • Invariant chain peptides enhancing or inhibiting the presentation of antigenic peptides by major histocompatibility complex class II molecules
    • Adams S, Humphreys RE: Invariant chain peptides enhancing or inhibiting the presentation of antigenic peptides by major histocompatibility complex class II molecules. Eur J Immunol 25:1693, 1995.
    • (1995) Eur J Immunol , vol.25 , pp. 1693
    • Adams, S.1    Humphreys, R.E.2
  • 67
    • 0000846523 scopus 로고
    • The structure of HLA-DR3 complexed with CLIP, an intermediate in peptide loading
    • Ghosh P, Amaya M, Mellins E, Wiley DC: The structure of HLA-DR3 complexed with CLIP, an intermediate in peptide loading. Nature 387:457, 1995.
    • (1995) Nature , vol.387 , pp. 457
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 68
    • 0029055938 scopus 로고
    • Antigen presentation mediated by recycling of surface HLA-DR molecules
    • Pinet V, Vergelli M, Martin R, Bakke O, Long EO: Antigen presentation mediated by recycling of surface HLA-DR molecules. Nature 375:603, 1995.
    • (1995) Nature , vol.375 , pp. 603
    • Pinet, V.1    Vergelli, M.2    Martin, R.3    Bakke, O.4    Long, E.O.5
  • 69
    • 0029790517 scopus 로고    scopus 로고
    • HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport
    • Liljedahl M, Kuwana T, Fung-Leung W-P, Jackson MR, Peterson PA, Karlsson L: HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport. EMBO J 15:4817, 1996.
    • (1996) EMBO J , vol.15 , pp. 4817
    • Liljedahl, M.1    Kuwana, T.2    Fung-Leung, W.-P.3    Jackson, M.R.4    Peterson, P.A.5    Karlsson, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.