Similarities and differences between the subchronic and withdrawal effects of clozapine and olanzapine on forelimb force steadiness

Psychopharmacology

Volumn 132, Issue 4, 1997, Pages 408-414

  Stanford, John A ^a   Fowler, Stephen C ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Antipsychotic; Atypical; Clozapine; Force; Forelimb; Neuroleptics; Olanzapine; Quipazine; Subchronic; Tolerance; Tremor; Trihexyphenidyl

Indexed keywords

CLOZAPINE; OLANZAPINE; QUIPAZINE; TRIHEXYPHENIDYL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FORELIMB; MALE; MUSCLE FORCE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TREMOR;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CLOZAPINE; DRUG TOLERANCE; FORELIMB; MALE; MUSCARINIC ANTAGONISTS; PIRENZEPINE; QUIPAZINE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN AGONISTS; SUBSTANCE WITHDRAWAL SYNDROME; TREMOR; TRIHEXYPHENIDYL;

EID: 0030770611     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050363     Document Type: Article

References (26)

1. 2C receptors. J Pharmacol Exp Ther 274: 1414-1424
2. Coward DM (1993) The pharmacology of clozapine-like atypical antipsychotics. In: Barnes TRE (ed) Antipsychotic drugs and their side-effects. Academic Press, London, pp 27-44
3. Das S, Fowler SC (1995a) Quipazine partially reversed the rhythm slowing and force decreasing effects of clozapine on rats' tongue movements. Soc Neurosci Abstr 25: 2107
4. Das S, Fowler SC (1995b) Acute and subchronic effects of clozapine on licking in rats: tolerance to disruptive effects on number of licks, but no tolerance to rhythm slowing. Psychopharmacology 120: 249-255
5. Das S, Fowler SC (1996) Similarity of clozapine's and olanzapine's acute effects on rats' lapping behavior. Psychopharmacology 123: 374-378
6. Faustman WO, Fowler SC (1982) An examination of methodological refinements, clozapine, and fluphenazine in the anhedonia paradigm. Pharmacol Biochem Behav 17: 987-993
7. Fischer PA, Baas H, Hefner R (1990) Treatment of Parkinsonian tremor with clozapine. J Neurotransm 2: 233-238
8. Ford KE, Fowler SC, Nail GI, (1979) Effects of clozapine and chlorpromazine upon operant response measures in rats. Pharmacol Biochem Behav 11: 239-241
9. Fowler SC, Liao RM, Skjoldager PD (1990) A new rodent model for neuroleptic-induced pseudoparkinsonism: low doses of haloperidol increase forelimb tremor in the rat. Behav Neurosci 104: 449-456
10. Fowler SC, Davison KH, Stanford JA (1994) Unlike haloperidol, clozapine slows and dampens rats' forelimb force oscillations and decreases force output in a press-while-licking behavioral task. Psychopharmacology 116: 19-25
11. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PPA (1994) International Union of Pharmacology Classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 46: 157-203
12. 2 antagonists on a conditioned avoidance task in rats. J Pharmacol Exp Ther 258: 118-123
13. Kaempf GL, Porter JH (1987) Differential effects of pimozide and clozapine on schedule-controlled and schedule-induced behaviors after acute and chronic administration. J Pharmacol Exp Ther 243: 437-445
14. Konicki PE, Jaskiw GE, Vrtunski PB (1994) Clozapine related force control deficits in chronic schizophrenic patients. Soc Neurosci Abstr 20: 854
15. Moore NA, Tye NC, Axton MS, Risius FC (1992) The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther 262: 545-551
16. Moore NA, Calligaro DO, Wong DT, Bymaster F, Tye NC (1993) The pharmacology of olanzapine and other new antipsychotic agents. Curr Opin Invest Drugs 2: 281-293
17. Sanger DJ (1985) The effects of clozapine on shuttle-box avoidance responding in rats: comparisons with haloperidol and chlordiazepoxide. Pharmacol Biochem Behav 23: 231-236
18. Schotte A, Janssen PFM, Gommeren W, Luvten WHML, Van-Compel P, Lesage AS, DeLoore K, Leysen JE (1996) Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology 124: 57-73
19. Shore D (1995) Clinical implications of clozapine discontinuation: report of an NIMH workshop. Schizophr Bull 21: 333-338
20. Stanford JA, Fowler SC (1994) Like clozapine, olanzapine slows rats' forelimb frequency oscillations in a press-while-licking behavioral task. Soc Neurosci Abstr 24: 1637
21. Stanford JA, Fowler SC (1997) Subchronic effects of clozapine and haloperidol on rats' forelimb force and duration during a press-while-licking task. Psychopharmacology 130:249-253
22. Stille G, Lauener H, Eichenberger E (1971) The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5-H-dibenzo[b,e][1, 4] diazepine (clozapine). Farmaco 26: 603-625
23. Verghese C, DeLeon J, Nair C, Simpson GM (1996) Clozapine withdrawal effects and receptor profiles of typical and atypical neuroleptics. Biol Psychiatry 1996: 135-138
24. Wiley JL, Compton AD, Porter JH (1994) Differential effects of clozapine and pimozide on fixed-ratio responding during repeated dosing. Pharmacol Biochem Behav 48: 253-257
25. Wilkinson, L (1990) SYSTAT: the system for statistics. SYSTAT, Inc., Evanston, Ill.
26. Young, AM, Goudie AJ (1995) Adaptive processes regulating tolerance to behavioral effects of drugs. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology: the fourth generation of progress. Raven Press, New York, pp 733-742