A study of the pharmacokinetics and tolerability of ritipenem acoxil in healthy volunteers following multiple oral dosing

Journal of Antimicrobial Chemotherapy

Volumn 40, Issue 2, 1997, Pages 291-294

  Poggesi, I ^a   Spinelli, R ^a   Frigerio, E ^a   Strolin Benedetti, M ^a,c   Carra', L ^a   Sassella, D ^a   Rimoldi, R ^b  

^a PFIZER INC   (United States)

^b Hospital of Varese   (Italy)

^c Zambon Group SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; RITIPENEM ACOXIL;

ADULT; AREA UNDER THE CURVE; ARTICLE; DRUG CLEARANCE; DRUG HALF LIFE; DRUG TOLERABILITY; HUMAN; HUMAN EXPERIMENT; MALE; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ADULT; ANALYSIS OF VARIANCE; CARBAPENEMS; HUMANS; KIDNEY; MALE; MIDDLE AGED;

EID: 0030770330     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/40.2.291     Document Type: Article

References (6)

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2. Albin, H., Vinçon, G., Jacob, C., Jannuzzo, M. G., Mignon, A. & Sassella, D. (1989). Tolerability and pharmacokinetics of FCE 22891 following multiple oral dosing. In Recent Advances in Chemotherapy - Antimicrobial Section 1. Proceedings of the 16th International Congress of Chemotherapy, Jerusalem, Israel, 1989 (Rubinstein, E. & Adam, D., Eds), pp. 85.1-.2. Lewin-Epstein, Jerusalem.
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5. Castellani, P., Dewland, P. M., Patel, B. T., Strolin-Benedetti, M. & Sassella, D. (1994). Pharmacokinetics of FCE 22101 Arginine after single intravenous 0.5 and 1.0 gram doses. In Recent Advances in Chemotherapy - Proceedings of the 18th International Congress of Chemotherapy, Stockholm, Sweden, 1993, pp. 355-6. American Society for Microbiology, Washington, DC.
6. 14C]FCE 22891, a penem antibiotic, following oral administration to healthy volunteers. Antimicrobial Agents and Chemotherapy 36, 1958-63.