Syndrome of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas (Carney complex): Breast imaging findings

Radiology

Volumn 205, Issue 1, 1997, Pages 221-227

  Courcoutsakis, Nikos A ^a   Chow, Catherine K ^a   Shawker, Thomas H ^a   Carney, J Aidan ^b   Stratakis, Constantine A ^c,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b MAYO CLINIC   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d GEORGETOWN UNIVERSITY HOSPITAL   (United States)

Author keywords

Breast neoplasms, diagnosis; Breast neoplasms, MR; Breast neoplasms, radiography; Breast neoplasms, US; Carney complex; Gadolinium

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BREAST ADENOMA; BREAST DUCT; BREAST FIBROADENOMA; BREAST TUMOR; CARNEY COMPLEX; CHROMOSOME 2P; CLINICAL ARTICLE; FEMALE; HUMAN; MAMMOGRAPHY; MYXOMA; NEURILEMOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SKIN PIGMENTATION; TUMOR CALCINOSIS;

EID: 0030770303     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiology.205.1.9314989     Document Type: Article

References (19)

1. Online Mendelian Inheritance in Man (OMIM). Available at: http://www.ncbi. nlm.nih.gov/Omim/. Accessed February 1997.
2. Carney JA, Gordon H, Carpenter PC, Shenoy V, Go VLW. The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine 1985; 64:270-283.
3. Carney JA. The Carney complex (myxomas, sporty pigmentation, endocrine overactivity, and schwannomas). Dermatol Clin North Am 1995; 13:19-26.
4. Carney JA, Young WF. Primary pigmented adrenocortical disease and its associated conditions. Endocrinologist 1992; 2:6-21.
5. Carney JA. Psammomatous melanotic schwannoma: a distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome. Am J Surg Pathol 1990; 14:206-222.
6. Premkumar A, Stratakis CA, Shawker TH, Papanicolaou DA, Chrousos GP. Testicular ultrasound in Carney complex. JCU 1997; 25:211-214.
7. Stratakis CA, Carney JA, Lin JP, et al. Carney complex, a familial multiple neoplasia and lentiginosis syndrome: analysis of 11 kindreds and linkage to the short arm of chromosome 2. J Clin Invest 1996; 97:699-705.
8. Carney JA, Toorkey BC. Myxoid fibroadenoma and allied conditions (myxomatosis) of the breast: a heritable disorder with special associations including cardiac and cutaneous myxomas. Am J Surg Pathol 1991; 15:713-721.
9. Carney JA, Toorkey BC. Ductal adenoma of the breast with tubular features: a probable component of the complex of myxomas, spotty pigmentation, endocrine overactivity, and schwannomas. Am J Surg Pathol 1991; 15:722-731.
10. Carney AJ, Stratakis C. Ductal adenoma of the breast. Am J Surg Pathol 1996; 20: 1154-1155.
11. Gollin SM, Jenkins RB, Swaney WP, Mulvihil JJ, Bartlet D Jr, Nwokoro NA. 10q26: consistent chromosomal breakpoint in two cardiac myxomas from a patient with Carney syndrome (abstr). Am J Hum Genet 1995; 57:A65.
12. Hachiya J, Seki T, Okada M, Nitatori T, Korenaga T, Furuya Y. MR imaging of the breast with Gd-DTPA enhancement: comparison with mammography and ultrasonography. Radiat Med 1991; 9:232-240.
13. Boetes C, Mus RDM, Holland R, et al. Breast tumors: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent. Radiology 1995; 197:743-747.
14. Jackson VP, Rothschild PA, Kreipke DL, Mail JT, Holden RH. The spectrum of sonographic findings of fibroadenoma of the breast. Invest Radiol 1986; 21:34-40.
15. Venta LA, Dudiak CM, Salomon CG, Flisak ME. Sonographic evaluation of the breast. RadioGraphics 1994; 14:29-50.
16. Greenstein Orel S, Schnall MD, LiVolsi VA, Troupin RH. Suspicious breast lesions: MR imaging with radiologic-pathologic correlation. Radiology 1994; 190:485-493.
17. Heywang SH, Wolf A, Pruss E, Hilbertz T, Eiermann W, Permanetter W. MR imaging of the breast with Gd-DTPA: use and limitations. Radiology 1989; 171:95-103.
18. Dupont W, Page DL, Pari FF, et al. Long term risk of breast cancer in women with fibroadenoma. N Engl J Med 1994; 331:10-15.
19. Stratakis CA, Courcoutsakis NA, Doppman JL, Carney JA, Shawker TH. Thyroid gland abnormalities in patients with the "syndrome of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas (Carney Complex)." J Clin Endocrinol Metab 1997; 82:2037-2043.