Multiple characteristics of a pentameric regulatory array endow the human α-subunit glycoprotein hormone promoter with trophoblast specificity and maximal activity

Molecular Endocrinology

Volumn 11, Issue 11, 1997, Pages 1669-1680

  Budworth, Paul R ^a   Quinn, Patrick G ^b   Nilson, John H ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHORIONIC GONADOTROPIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; FOLLITROPIN; GLYCOPROTEIN; HORMONE; LUTEINIZING HORMONE; THYROTROPIN; TRANSCRIPTION FACTOR;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TATA BOX; TISSUE SPECIFICITY; TROPHOBLAST;

CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HUMANS; MACROMOLECULAR SUBSTANCES; MUTAGENESIS, SITE-DIRECTED; ORGAN SPECIFICITY; PREGNANCY; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TATA BOX; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TROPHOBLASTS; TUMOR CELLS, CULTURED;

EID: 0030769066     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.11.11.1669     Document Type: Article

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