Genetics of native airway responsiveness in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 156, Issue 4 II SUPPL., 1997, Pages

  De Sanctis, George T ^a   Drazen, Jeffrey M ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ASTHMA; BRONCHUS HYPERREACTIVITY; CONFERENCE PAPER; GENE LOCUS; GENE SEGREGATION; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT;

EID: 0030768970     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.156.4.12-tac-2     Document Type: Conference Paper

References (26)

1. National Heart, Lung, and Blood Institute. 1991. Guidelines for the diagnosis and management of asthma. National Asthma Education Program. J. Allergy Clin, Imnunol. 88(3, Pt. 2):425-534. Expert Panel Report.
2. Hirshman, C. A., H. Downes, and L. Veith. 1984. Airway responses in offspring of dogs with and without airway hyperreactivity. J. Appl. Physiol. 56:1272-1277.
3. Konno, S., M. Adachi, T. Matsuura, K. Sunouchi, H. Hoshino, A. Okazawa, H. Kobayashi, and T. Takahashi. 1993. Bronchial reactivity to methacholine and serotonin in six inbred mouse strains. Arerugi 42(1):42-47.
4. Levitt, R. C., and W. Mitzner. 1988. Expression of airway hyperreactivity to acetylcholine as a simple autosomal recessive trait in mice. FASEB J. 2:2605-2608.
5. Levitt, R. C., and W. Mitzner. 1989. Autosomal recessive inheritance of airway hyperreactivity to 5-hydroxytryptamine. J. Appl. Physiol. 67:1125-1132.
6. Pattemore, P. K., M. I. Asher, A. C. Harrison, E. A. Mitchell, H. H. Rea, and A. W. Stewart. 1990. The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms. Am. Rev. Respir. Dis. 142:549-554.
7. Martin, T. R., N. P. Gerard, S. J. Galli, and J. M. Drazen. 1988. Pulmonary responses to bronchoconstrictor agonists in the mouse. J. Appl. Physiol. 64:2318-2323.
8. Kleeberger, S. R., D. J. Bassett, G. J. Jakab, and R. C. Levitt. 1990. A genetic model for evaluation of susceptibility to ozone-induced inflammation. Am. J. Physiol. 258:L313-L320.
9. Renz, H., H. R. Smith, J. E. Henson, B. S. Ray, C. G. Irvin, and E. W. Gelfand. 1992. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J. Allergy Clin. Imnmnol. 89:1127-1138.
10. Dietrich, W. F., J. C. Miller, R. G. Steen, M. Merchant, D. Damron, R. Nahf, A. Gross, D. C. Joyce, M. Wessel, and R. D. Dredge. 1994. A genetic map of the mouse with 4,006 simple sequence length polymorphisms. Nat. Genet. 7:220-245.
11. Nadeau, J. H., and B. A. Taylor. 1984. Lengths of chromosomal segments conserved since divergence of man and mouse. Proc. Natl. Acad. Sci. U.S.A. 81:814-818.
12. Viskochil, D., A. M. Buchberg, G. Xu, R. M. Cawthon, J. Stevens, R. K. Wolff, M. Culver, J. C. Carey, N. G. Copeland, and N. A. Jenkins. 1990. Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell 62:187-192.
13. Snapper, J. R., J. M. Drazen, S. H. Loring, W. Schneider, and R. J. Ingram. 1978. Distribution of pulmonary responsiveness to aerosol histamine in dogs. J. Appl. Physiol. 44:734-742.
14. Pauwels, R., M. Van der Straeten, and J. Weyne. 1985. Genetic factors in non-specific bronchial reactivity in rats. Eur. J. Respir Dis. 66:98-104.
15. Douglas, J. S., P. Ridgway, and C. Brink. 1977. Airway responses of the guinea pig in vivo and in vitro. J. Pharmacol. Exp. Ther. 202:116-124.
16. Longphre, M., and S. R. Kleeberger. 1995. Susceptibility to platelet-activating factor-induced airway hyperreactivity and hyperpermeability: interstrain variation and genetic control. Am. J. Respir. Cell Mol. Biol. 13:586-594.
17. Levitt, R. C., W. Mitzner, and S. R. Kleeberger. 1990. A genetic approach to the study of lung physiology: understanding biological variability in airway responsiveness. Am. J. Physiol. 258:L157-L164.
18. Gavett, S. H., and M. Wills-Karp. 1993. Elevated lung G protein levels and muscarinic receptor affinity in a mouse model of airway hyperreactivity. Am. J. Physiol. 265:L493-L500.
19. Levitt, R. C., and S. E. Ewart. 1995. Genetic susceptibility to atracurium-induced bronchoconstriction. Am. J. Respir. Crit. Care Med. 151:1537-1542.
20. Martin, T. R., M. L. Cohen, and J. M. Drazen. 1994. Serotonin-induced pulmonary responses are mediated by the 5-HT receptor in the mouse. J. Pharmacol. Exp. Ther. 268:104-109.
21. De Sanctis, G. T., M. Merchant, D. R. Beier, R. D. Dredge, J. K. Grobholz, T. R. Martin, E. S. Lander, and J. M. Drazen. 1995. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat. Genet. 11(2):150-154.
22. Todd, J. A., T. J. Aitman, R. J. Cornall, S. Ghosh, J. R. Hall, C. M. Hearne, A. M. Knight, J. M. Love, M. A. McAleer, and J. B. Prins. 1991. Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature 351:542-547.
23. Jacob, H. J., K. Lindpaintner, S. E. Lincoln, K. Kusumi, R. K. Bunker, Y. P. Mao, D. Ganten, V. J. Dzau, and E. S. Lander. 1991. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. Cell 67:213-224.
24. Paigen, B., D. Mitchell, K. Reue, A. Morrow, J. Lusis, and R. C. LeBoeuf. 1987. Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. Proc. Natl. Acad. Sci. U.S.A. 84:3763-3767.
25. Ewart, S. L., W. Mitzner, D. A. DiSilvestre, D. A. Meyers, and R. C. Levitt. 1996. Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6. Am. J. Respir. Cell Mol. Biol. 14(5):487-495.
26. Wright, S. 1968. Evolution and the Genetics of Populations, Volume 1: Genetic and Biometric Foundations. University of Chicago Press, Chicago.