Overview of biological themes in PTSD

Annals of the New York Academy of Sciences

Volumn 821, Issue , 1997, Pages 1-9

  Pitman, Roger K ^a,b,c  

^a Manchester VA Medical Center   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLISM; ANXIETY NEUROSIS; CONFERENCE PAPER; EMOTION; GENETIC ASSOCIATION; HIPPOCAMPUS; HUMAN; IMAGING; INJURY; MEDICAL RESEARCH; MENTAL DISEASE; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; SELF REPORT;

EID: 0030767917     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48264.x     Document Type: Conference Paper

References (27)

1. AMERICAN PSYCHIATRIC ASSOCIATION. 1994. Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. American Psychiatric Association. Washington, DC.
2. AMERICAN PSYCHIATRIC ASSOCIATION. 1980. Diagnostic and Statistical Manual of Mental Disorders, 3rd Ed. American Psychiatric Association. Washington, DC.
3. PITMAN, R. K. & S. P. ORR. 1993. Psychophysiologic testing for post-traumatic stress disorder: Forensic psychiatric application. Bull. Am. Acad. Psychiatry & Law 21: 37-52.
4. BREMNER, D., P. RANDALL, T. N. SCOTT, R. A. BRONEN, J. P. SEIBYL, S. M. SOUTHWICK, R. C. DELANEY, G. MCCARTY, D. S. CHARNEY & R. B. INNIS. 1995. MRI-based measurements of hippocampal volume in combat-related posttraumatic stress disorder. Am. J. Psychiatry 152: 973-981.
5. GURVITS, T. V., M. E. SHENTON, H. HOKAMA, H. OHTA, N. B. LASKO, M. W. GILBERTSON, S. P. ORR, R. KIKINIS, F. A. JOLESZ, R. W. MCCARLEY & R. K. PITTMAN. 1996. Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol. Psychiatry 40: 1091-1099.
6. BREMNER, J. D., P. RANDALL, E. VERMETTEN, L. STAIB, R. A. BRONEN, C. MAZURÉ, S. CAPELLI, G. MCCARTHY, R. B. INNIS & D. S. CHARNEY. 1997. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse. A preliminary report. Biol. Psychiatry 41: 23-32.
7. STEIN, M. B., C. HANNAH, C. KOVEROLA & G. MCCLARTY. 1995. Neuroanatomic and cognitive correlates of early abuse. Am. Psychiatric Assoc. Syllabus & Proc. Summary 148: 113.
8. RAUCH, S. L., B. A. VAN DER KOLK, R. E. FISLER, N. M. ALPERT, S. P. ORR, C. R. SAVAGE, A. J. FISCHMAN, M. A. JENIKE & R. K. PITMAN. 1996. A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script driven imagery. Arch. Gen. Psychiatry 53: 380-387.
9. SHIN, L. M., S. M. KOSSLYN, R. J. MCNALLY, N. M. ALPERT, W. L. THOMPSON, S. L. RAUCH, M. A. MACKLIN & R. K. PITMAN. 1997. Visual imagery and perception in posttraumatic stress disorder: A positron emission tomographic investigation. Arch. Gen. Psychiatry 54: 233-241.
10. HESTON, L. 1987. What about environment? Paul Hoch Award Lecture. 77th Annual Meeting of the American Psychopathological Association. New York, NY.
11. PITMAN, R. K., S. P. ORR & A. Y. SHALEV. 1993. Once bitten, twice shy: Beyond the conditioning model of PTSD. Biol. Psychiatry 33: 145-146.
12. DARWIN, C. 1965. The Expression of the Emotions in Man and Animals. University of Chicago Press. Chicago, IL. (Reprinted from John Murray. London, 1872).
13. MCGAUGH, J. L. 1990. Significance and remembrance: The role of neuromodulatory systems. Psychol. Sci. 1: 15-25.
14. LEDOUX, J. E. 1990. Information flow from sensation to emotion: Plasticity in the neural computation of stimulus value. In Learning Computational Neuroscience: Foundations of Adaptive Networks. M. Gabriel & J. Moore, Eds.: 3-51. MIT Press. Cambridge, MA.
15. SELYE, H. 1946. The general adaptation syndrome and the diseases of adaptation. J. Clin. Endocrinol. 6: 117-230.
16. BOSCARINO, J. A. 1996. Post-traumatic stress disorder, exposure to combat, and lower plasma cortisol among Vietnam veterans: Findings and clinical implications. J. Consult. Clin. Psychol. 63: 191-201.
17. YEHUDA, R., M. H. TEICHER, R. L. TRESTMAN, R. A. LEVENGOOD & L. J. SIEVER. 1996. Cortisol regulation in posttraumatic stress disorder and major depression: A chronobiological analysis. Biol. Psychiatry 40: 79-88.
18. UNO, H., R. TARARA, J. ELSE, M. SULEMAN & R. M. SAPOLSKY. 1989. Hippocampal damage associated with prolonged and fatal stress in primates. J. Neurosci. 9: 1705-1711.
19. WATANABE, Y., E. GOULD & B. S. MCEWEN. 1992. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res. 588: 341-345.
20. DOUGLAS, R. J. 1972. Pavlovian conditioning and the brain. In Inhibition and Learning. R. A. Boakes & M. S. Halliday, Eds.: 529-553. Academic. London.
21. ESKAY, R. L., T. CHAUTARD, T. TORDA, R. I. DAOUD & C. HAMELINK. 1995. Alcohol, corticosteroids, energy utilization, and hippocampal endangerment. Ann. N.Y. Acad. Sci. 771: 105-114.
22. LYONS, M. J., J. GOLDBERG, S. A. EISEN, W. R. TRUE, J. MEYER, M. T. TSUANG & W. G. HENDERSON. 1993. Do genes influence exposure to trauma?: A twin study of combat. Am. J. Med. Genet. (Neuropsyschiatr. Genet.) 14: 22-27.
23. TRUE, W. R., J. RICE, S. A. EISEN, A. C. HEATH, J. GOLDBERG, M. J. LYONS & J. NOWAK. 1993. A twin study of genetic and environmental contributions to liability for posttraumatic stress symptoms. Arch. Gen. Psychiatry 50: 257-264.
24. GURVITS, T. V., N. B. LASKO, S. C. SCHACHTER, A. A. KUHNE, S. P. ORR & R. K. PITMAN. 1993. Neurological status of Vietnam veterans with chronic post-traumatic stress disorder. J. Neuropsychiatry Clin. Neurosci. 5: 183-188.
25. HUESSY, H. R. 1989. PTSD and sexually abused children. J. Am. Acad. Child Adolesc. Psychiatry 29: 298.
26. ORR, S. P., N. B. LASKO, L. J. METZGER, N. J. BERRY, C. E. AHERN & R. K. PITMAN. 1997. Psychophysiologic assessment of PTSD in adult female victims of childhood sexual abuse. Ann. N.Y. Acad. Sci., this volume.
27. CHROUSOS, G. P., R. MCCARTY, K. PACÁK, G. CIZZA, E. STERNBERG, P. W. GOLD & R. KVETN̄ANSKÝ. 1995. Stress: Basic mechanisms and clinical implications. Ann. N.Y. Acad. Sci. Vol. 771.