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Volumn 100, Issue 8, 1997, Pages 613-622

Neurochemical alterations and current pharmacological strategies in the treatment of traumatic brain injury;Neurochemische veranderungen und aktuelle pharmakologische ansatze beim schadel-hirn-trauma

Author keywords

Brain injury; Pathophysiology; Pharmacotherapy

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CALCIUM ANTAGONIST; CORTICOSTEROID; ELIPRODIL; GANGLIOSIDE; INDOMETACIN; METHYLPREDNISOLONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NIMODIPINE; OPIATE ANTAGONIST; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTIRELIN; THROMBOCYTE ACTIVATING FACTOR; TOCOPHEROL; AMINO ACID RECEPTOR BLOCKING AGENT; ARACHIDONIC ACID; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; EXCITATORY AMINO ACID; REACTIVE OXYGEN METABOLITE;

EID: 0030767674     PISSN: 01775537     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001130050166     Document Type: Article
Times cited : (2)

References (107)
  • 1
    • 0028173069 scopus 로고
    • 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity
    • 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res 663: 237-243
    • (1994) Brain Res , vol.663 , pp. 237-243
    • Aikake, A.1    Kaneko, S.2    Tamura, Y.3    Nakata, N.4
  • 2
    • 0023626732 scopus 로고
    • Outcome after severe head injury. Relationship to mass lesions, diffuse injury, and ICP course in pediatric and adult patients
    • Albenco AM, Ward JD, Choi SC, Marmarou A, Young HF (1987) Outcome after severe head injury. Relationship to mass lesions, diffuse injury, and ICP course in pediatric and adult patients. J Neurosurg 67: 648-656
    • (1987) J Neurosurg , vol.67 , pp. 648-656
    • Albenco, A.M.1    Ward, J.D.2    Choi, S.C.3    Marmarou, A.4    Young, H.F.5
  • 3
    • 0020660955 scopus 로고
    • Cerebral arterial spasm - A controlled trial of nimodipine in patients with subarachnoid hemorrhage
    • Allen GS, Ahn HS, Preziosi TJ et al. (1983) Cerebral arterial spasm - a controlled trial of nimodipine in patients with subarachnoid hemorrhage. N Engl J Med 308: 619-624
    • (1983) N Engl J Med , vol.308 , pp. 619-624
    • Allen, G.S.1    Ahn, H.S.2    Preziosi, T.J.3
  • 4
    • 0022224135 scopus 로고
    • Lipid hydrolysis and peroxidation in injured spinal cord: Partial protection with methylprednisolone or vitamin E and selenium
    • Anderson DK, Saunders RD, Demediuk P et al. (1985) Lipid hydrolysis and peroxidation in injured spinal cord: partial protection with methylprednisolone or vitamin E and selenium. Cent Nerv Syst Trauma 2: 257-267
    • (1985) Cent Nerv Syst Trauma , vol.2 , pp. 257-267
    • Anderson, D.K.1    Saunders, R.D.2    Demediuk, P.3
  • 6
    • 0024591312 scopus 로고
    • Release of glutamate and free fatty acids in vasogenic edema
    • Baethmann A, Maier-Hauff K et al. (1989) Release of glutamate and free fatty acids in vasogenic edema. J Neurosurg 70: 578-591
    • (1989) J Neurosurg , vol.70 , pp. 578-591
    • Baethmann, A.1    Maier-Hauff, K.2
  • 7
    • 0025863565 scopus 로고
    • A trial of the effect of nimodipine on outcome after head injury
    • Bailey I, Bell A, Gray J et al. (1991) A trial of the effect of nimodipine on outcome after head injury. Acta Neurochir Wien 110: 97-105
    • (1991) Acta Neurochir Wien , vol.110 , pp. 97-105
    • Bailey, I.1    Bell, A.2    Gray, J.3
  • 8
    • 0027295901 scopus 로고
    • Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans
    • Baker AJ, Moulton RJ, MacMillan VH, Shedden PM (1993) Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. J Neurosurg 79: 369-372
    • (1993) J Neurosurg , vol.79 , pp. 369-372
    • Baker, A.J.1    Moulton, R.J.2    MacMillan, V.H.3    Shedden, P.M.4
  • 9
    • 0019270386 scopus 로고
    • Membrane lipids in the pathogenesis of brain edema. Phospholipids and arachidonic acid, the earliest membrane components changed at the on-set of ischemia
    • Bazan NG, DeTuro EBR (1980) Membrane lipids in the pathogenesis of brain edema. Phospholipids and arachidonic acid, the earliest membrane components changed at the on-set of ischemia. Adv Neurol 28: 197-205
    • (1980) Adv Neurol , vol.28 , pp. 197-205
    • Bazan, N.G.1    DeTuro, E.B.R.2
  • 10
    • 0023819308 scopus 로고
    • Early post-ischemic 45Ca accumulation in rat dentate hilus
    • Benveniste H, Diemer NH (1988) Early post-ischemic 45Ca accumulation in rat dentate hilus. J Cereb Blood Flow Metab 8: 713-719
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 713-719
    • Benveniste, H.1    Diemer, N.H.2
  • 11
    • 0021857465 scopus 로고
    • Leukotrienes increase blood-brain barrier permeability following intraparenchymal injections in rats
    • Black KL, Hoff JT (1985) Leukotrienes increase blood-brain barrier permeability following intraparenchymal injections in rats. Ann Neurol 18: 349-351
    • (1985) Ann Neurol , vol.18 , pp. 349-351
    • Black, K.L.1    Hoff, J.T.2
  • 12
    • 0025231457 scopus 로고
    • Intraventricular norepinephrine facilitates motor recovery following sensorimotor cortex injury
    • Boyeson MG, Feeney DM (1990) Intraventricular norepinephrine facilitates motor recovery following sensorimotor cortex injury. Pharmacol Biochem Behav 35: 497-501
    • (1990) Pharmacol Biochem Behav , vol.35 , pp. 497-501
    • Boyeson, M.G.1    Feeney, D.M.2
  • 13
    • 0020673332 scopus 로고
    • Megadose steroids in severe head injury. Results of a prospective double-blind clinical trial
    • Braakmann R, Schouten HJA, Blaauw-van Dishoek M, Minderhoud JM (1983) Megadose steroids in severe head injury. Results of a prospective double-blind clinical trial. J Neurosurg 58: 326-330
    • (1983) J Neurosurg , vol.58 , pp. 326-330
    • Braakmann, R.1    Schouten, H.J.A.2    Blaauw-van Dishoek, M.3    Minderhoud, J.M.4
  • 14
    • 0025344617 scopus 로고
    • A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study
    • Bracken MB, Shepard MJ, Collins WF et al. (1990) A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 322: 1405-1411
    • (1990) N Engl J Med , vol.322 , pp. 1405-1411
    • Bracken, M.B.1    Shepard, M.J.2    Collins, W.F.3
  • 15
    • 0025324112 scopus 로고
    • ABC of major trauma. Head injuries
    • Bullock R, Teasdale G (1990) ABC of major trauma. Head injuries. Br Med J 300: 1576-1579
    • (1990) Br Med J , vol.300 , pp. 1576-1579
    • Bullock, R.1    Teasdale, G.2
  • 16
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi DW (1988) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11: 465-469
    • (1988) Trends Neurosci , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 17
    • 0028143148 scopus 로고
    • The high affinity uptake system for excitatory amino acids in the brain
    • Danbolt NC (1994) The high affinity uptake system for excitatory amino acids in the brain. Progr Neurobiol 44: 369-377
    • (1994) Progr Neurobiol , vol.44 , pp. 369-377
    • Danbolt, N.C.1
  • 20
    • 0023819437 scopus 로고
    • Highdose barbiturate control of elevated intracranial pressure in patients with severe head injury
    • Eisenberg HM, Frankowsky RF, Contant CF, Marshall LF, Walker MD (1988) Highdose barbiturate control of elevated intracranial pressure in patients with severe head injury. J Neurosurg 69: 15-23
    • (1988) J Neurosurg , vol.69 , pp. 15-23
    • Eisenberg, H.M.1    Frankowsky, R.F.2    Contant, C.F.3    Marshall, L.F.4    Walker, M.D.5
  • 22
    • 0019839760 scopus 로고
    • Cycloocygenase products of arachidonic acid metabolism in cat cerebral cortex after experimental concussive brain injury
    • Ellis EF, Wright KF, Wei EP, Kontos HA (1981) Cycloocygenase products of arachidonic acid metabolism in cat cerebral cortex after experimental concussive brain injury. J Neurochem 37: 892-896
    • (1981) J Neurochem , vol.37 , pp. 892-896
    • Ellis, E.F.1    Wright, K.F.2    Wei, E.P.3    Kontos, H.A.4
  • 23
    • 0024379203 scopus 로고
    • TRH analog YM-14673 improves outcome following traumatic brain and spinal cord injury in rats: Dose-response studies
    • Faden AI (1989) TRH analog YM-14673 improves outcome following traumatic brain and spinal cord injury in rats: dose-response studies. Brain Res 486: 228-235
    • (1989) Brain Res , vol.486 , pp. 228-235
    • Faden, A.I.1
  • 24
    • 0023752736 scopus 로고
    • Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats
    • Faden AI, Lemke M, Demediuk P (1988) Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats. Brain Res 463: 63-68
    • (1988) Brain Res , vol.463 , pp. 63-68
    • Faden, A.I.1    Lemke, M.2    Demediuk, P.3
  • 25
    • 0026540898 scopus 로고
    • Pharmacological strategies in CNS trauma
    • Faden AI, Salzman S (1992) Pharmacological strategies in CNS trauma. Trends Pharmacol Sci 13: 29-35
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 29-35
    • Faden, A.I.1    Salzman, S.2
  • 26
    • 0024436090 scopus 로고
    • Thyreotropin-releasing hormone and central nervous system trauma
    • Faden AI, Vink R, McIntosh TK (1989) Thyreotropin-releasing hormone and central nervous system trauma. Ann N Y Acad Sci 553: 380-384
    • (1989) Ann N Y Acad Sci , vol.553 , pp. 380-384
    • Faden, A.I.1    Vink, R.2    McIntosh, T.K.3
  • 27
    • 0025005205 scopus 로고
    • The role of calcium ions in toxic cell injury
    • Farber JL (1990) The role of calcium ions in toxic cell injury. Envir Health Perspect 84: 107-111
    • (1990) Envir Health Perspect , vol.84 , pp. 107-111
    • Farber, J.L.1
  • 28
    • 0022436652 scopus 로고
    • Descriptive epidemiologic studies of head injury in the United States: 1974-1984
    • Frankowski RF (1986) Descriptive epidemiologic studies of head injury in the United States: 1974-1984. Adv Psychosom Med 16: 153-172
    • (1986) Adv Psychosom Med , vol.16 , pp. 153-172
    • Frankowski, R.F.1
  • 30
    • 0018362204 scopus 로고
    • Thyrotropin-releasing hormone (TRH): Enhancement of dopamine dependent circling behavior and its own circling-indudng effect in unilateral striatal lesioned animals
    • Fukuda M, Miyamoto M, Narumi S, Nagai Y, Shima T, Nagawa Y (1979) Thyrotropin-releasing hormone (TRH): Enhancement of dopamine dependent circling behavior and its own circling-indudng effect in unilateral striatal lesioned animals. Nippon Yakurigaku Zasshi 75: 251-270
    • (1979) Nippon Yakurigaku Zasshi , vol.75 , pp. 251-270
    • Fukuda, M.1    Miyamoto, M.2    Narumi, S.3    Nagai, Y.4    Shima, T.5    Nagawa, Y.6
  • 31
    • 0026432654 scopus 로고
    • Recovery of motor function after spinal-cord injury - A randomized, placebo-controlled trial with GM-1 ganglioside
    • Geisler FH, Dorsey FC, Coleman WP (1991) Recovery of motor function after spinal-cord injury - a randomized, placebo-controlled trial with GM-1 ganglioside. N Engl J Med 324: 1829-1838
    • (1991) N Engl J Med , vol.324 , pp. 1829-1838
    • Geisler, F.H.1    Dorsey, F.C.2    Coleman, W.P.3
  • 32
    • 0027396850 scopus 로고
    • Mechanisms of brain injury
    • Gennarelli TA (1993) Mechanisms of brain injury. J Emerg Med 1: 5-11
    • (1993) J Emerg Med , vol.1 , pp. 5-11
    • Gennarelli, T.A.1
  • 33
    • 0021189271 scopus 로고
    • High dose glucocorticoids in the management of severe head injury
    • Giannotta SL, Weiss MH, Apuzzo MLJ, Martin E (1984) High dose glucocorticoids in the management of severe head injury. Neurosurgery 15: 497-501
    • (1984) Neurosurgery , vol.15 , pp. 497-501
    • Giannotta, S.L.1    Weiss, M.H.2    Apuzzo, M.L.J.3    Martin, E.4
  • 34
    • 0029098104 scopus 로고
    • Treatment of patients with severe head injury by triamcinolone: A prospective, controlled multicenter clinical trail of 396 cases
    • Grumme T, Baethmann A, Kolodziejczyk D et al. (1995) Treatment of patients with severe head injury by triamcinolone: a prospective, controlled multicenter clinical trail of 396 cases. Res Exp Med 195 217-229
    • (1995) Res Exp Med , vol.195 , pp. 217-229
    • Grumme, T.1    Baethmann, A.2    Kolodziejczyk, D.3
  • 36
    • 0026500593 scopus 로고
    • The neuroprotective pharmacology of methylprednisolone
    • Hall ED (1992) The neuroprotective pharmacology of methylprednisolone. J Neurosurg 76: 13-22
    • (1992) J Neurosurg , vol.76 , pp. 13-22
    • Hall, E.D.1
  • 37
    • 0027400110 scopus 로고
    • Brain hydroxyl radical generation in acute experimental head injury
    • Hall ED, Andrus PK, Yonkers PA (1993) Brain hydroxyl radical generation in acute experimental head injury. J Neurochem 60: 588-594
    • (1993) J Neurochem , vol.60 , pp. 588-594
    • Hall, E.D.1    Andrus, P.K.2    Yonkers, P.A.3
  • 38
    • 0022921520 scopus 로고
    • Role of lipid peroxidation in post-traumatic spinal cord degeneration: A review
    • Hall ED, Braughler JM (1986) Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review. Cent Nerv Syst Trauma 3: 281-294
    • (1986) Cent Nerv Syst Trauma , vol.3 , pp. 281-294
    • Hall, E.D.1    Braughler, J.M.2
  • 39
    • 0020645702 scopus 로고
    • 2, indomethacin, and heparin improves neurological recovery after spinal trauma in cats
    • 2, indomethacin, and heparin improves neurological recovery after spinal trauma in cats. J Neurosurg 58: 749-754
    • (1983) J Neurosurg , vol.58 , pp. 749-754
    • Hallenbeck, J.M.1    Jacobs, T.P.2    Faden, A.I.3
  • 40
    • 0020549344 scopus 로고
    • Effects of naloxone on systemic and cerebral responses to experimental concussive brain injury in cats
    • Hayes RL, Galinat BJ, Kulkarne P, Becker DP (1983) Effects of naloxone on systemic and cerebral responses to experimental concussive brain injury in cats. J Neurosurg 58: 720-728
    • (1983) J Neurosurg , vol.58 , pp. 720-728
    • Hayes, R.L.1    Galinat, B.J.2    Kulkarne, P.3    Becker, D.P.4
  • 42
    • 0024434811 scopus 로고
    • Formation and function of eicosanoids in the central nervous system
    • Hertting G, Seregi A (1990) Formation and function of eicosanoids in the central nervous system. Ann NY Acad Sci 559 84-99
    • (1990) Ann NY Acad Sci , vol.559 , pp. 84-99
    • Hertting, G.1    Seregi, A.2
  • 43
    • 3042881166 scopus 로고
    • Schädel-Hirn-Trauma
    • Ruter A, Trentz O, Wagner M (Hrsg) Urban & Schwarzenberg, Munchen Wien Baltimore
    • Imhof HG (1995) Schädel-Hirn-Trauma. In: Ruter A, Trentz O, Wagner M (Hrsg) Unfallchirurgie. Urban & Schwarzenberg, Munchen Wien Baltimore, pp 255-282
    • (1995) Unfallchirurgie , pp. 255-282
    • Imhof, H.G.1
  • 44
    • 0028096701 scopus 로고
    • Pharmacological evidence for a role of long-term potentiation in memory
    • Izquierdo I (1994) Pharmacological evidence for a role of long-term potentiation in memory. FASEB J 8: 1139-1145
    • (1994) FASEB J , vol.8 , pp. 1139-1145
    • Izquierdo, I.1
  • 45
    • 0023801196 scopus 로고
    • Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms
    • Jan M, Buchheit F, Tremoulet M (1988) Therapeutic trial of intravenous nimodipine in patients with established cerebral vasospasm after rupture of intracranial aneurysms. Neurosurgery 23: 154-157
    • (1988) Neurosurgery , vol.23 , pp. 154-157
    • Jan, M.1    Buchheit, F.2    Tremoulet, M.3
  • 46
    • 0021315029 scopus 로고
    • Exogenous gangliosides enhance recovery from cns injury
    • Karpiak SE (1984) Exogenous gangliosides enhance recovery from cns injury. Adv Exp Med Biol 174 489-497
    • (1984) Adv Exp Med Biol , vol.174 , pp. 489-497
    • Karpiak, S.E.1
  • 47
    • 0025242563 scopus 로고
    • Massive increase in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury
    • Katayama Y, Becker DP, Tamura T, Hovda DA (1990) Massive increase in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 889-900
    • (1990) J Neurosurg , pp. 889-900
    • Katayama, Y.1    Becker, D.P.2    Tamura, T.3    Hovda, D.A.4
  • 48
    • 0024332424 scopus 로고
    • Somatostatin presynaptically inhibits transmitter release in feline parasympathetic ganglia
    • Katayama Y, Hirai K (1989) Somatostatin presynaptically inhibits transmitter release in feline parasympathetic ganglia. Brain Res 487: 62-68
    • (1989) Brain Res , vol.487 , pp. 62-68
    • Katayama, Y.1    Hirai, K.2
  • 49
    • 0025138196 scopus 로고
    • Intravenous glutamate enhances edema formation after a freezing lesion
    • Kempski O, van Adrian U, Schurer L, Baethmann A (1990) Intravenous glutamate enhances edema formation after a freezing lesion. Adv Neurol 52: 219-222
    • (1990) Adv Neurol , vol.52 , pp. 219-222
    • Kempski, O.1    Van Adrian, U.2    Schurer, L.3    Baethmann, A.4
  • 50
    • 0014046826 scopus 로고
    • Neuropathological aspects of brain edema
    • Klatzo I (1967) Neuropathological aspects of brain edema. J Neuropath Exp Neurol 26: 1-14
    • (1967) J Neuropath Exp Neurol , vol.26 , pp. 1-14
    • Klatzo, I.1
  • 52
    • 0022628380 scopus 로고
    • Superoxide production in experimental brain injury
    • Kontos HA, Wei EP (1986) Superoxide production in experimental brain injury. J Neurosurg 64: 803-807
    • (1986) J Neurosurg , vol.64 , pp. 803-807
    • Kontos, H.A.1    Wei, E.P.2
  • 53
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal M, Pietri S, Culcasi M, Bockaert J (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364: 535-537
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 54
    • 0024361542 scopus 로고
    • Nimodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in cerebrovascular disease
    • Langley MS, Sorkin EM (1989) Nimodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in cerebrovascular disease. Drugs 37: 669-699
    • (1989) Drugs , vol.37 , pp. 669-699
    • Langley, M.S.1    Sorkin, E.M.2
  • 56
    • 0024454933 scopus 로고
    • Combined effect of respiratorinduced ventilation and superoxide dismutase in experimental brain injury
    • Levasseur JE, Patterson JJ, Ghatak NR, Kontos HA, Choi SC (1989) Combined effect of respiratorinduced ventilation and superoxide dismutase in experimental brain injury. J Neurosurg 71 573-577
    • (1989) J Neurosurg , vol.71 , pp. 573-577
    • Levasseur, J.E.1    Patterson, J.J.2    Ghatak, N.R.3    Kontos, H.A.4    Choi, S.C.5
  • 57
    • 0025738206 scopus 로고
    • Platelet-activating factor in stroke and brain injury
    • Lindsberg PJ, Hallenbeck JM, Feuerstein G (1991) Platelet-activating factor in stroke and brain injury. Ann Neurol 30: 117-129
    • (1991) Ann Neurol , vol.30 , pp. 117-129
    • Lindsberg, P.J.1    Hallenbeck, J.M.2    Feuerstein, G.3
  • 58
    • 0027508237 scopus 로고
    • Prospects for clinically tolerated NMDA antagonists: Open-channel blockers and alternative redox states of nitric oxide
    • Lipton SA (1993) Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide. Trends Neurosci 16: 527-532
    • (1993) Trends Neurosci , vol.16 , pp. 527-532
    • Lipton, S.A.1
  • 60
    • 0023951211 scopus 로고
    • Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat
    • Lyeth BG, Dixon CE, Hamm RJ, Jenkins LW, Young HF, Stonnington HH, Hayes RL (1988) Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat. Brain Res 448: 88-97
    • (1988) Brain Res , vol.448 , pp. 88-97
    • Lyeth, B.G.1    Dixon, C.E.2    Hamm, R.J.3    Jenkins, L.W.4    Young, H.F.5    Stonnington, H.H.6    Hayes, R.L.7
  • 61
    • 0027527251 scopus 로고
    • Adenosine triphosphate depletion reverses sodium - Dependent neuronal uptake of glutamate in rat hippocampal slices
    • Madl JE, Burgesser K (1993) Adenosine triphosphate depletion reverses sodium - dependent neuronal uptake of glutamate in rat hippocampal slices. J Neurochem 13: 4429-4444
    • (1993) J Neurochem , vol.13 , pp. 4429-4444
    • Madl, J.E.1    Burgesser, K.2
  • 62
    • 0027377278 scopus 로고
    • Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: A review
    • McIntosh TK (1993) Novel pharmacologic therapies in the treatment of experimental traumatic brain injury: a review. J Neurotrauma 10: 215-261
    • (1993) J Neurotrauma , vol.10 , pp. 215-261
    • McIntosh, T.K.1
  • 63
    • 0023473202 scopus 로고
    • Endogenous opioids may mediate secondary damage after experimental brain injury
    • McIntosh TK, Hayes RL, DeWitt DS, Agura V, Faden AI (1987) Endogenous opioids may mediate secondary damage after experimental brain injury. Am J Physiol 253: E 565-574
    • (1987) Am J Physiol , vol.253
    • McIntosh, T.K.1    Hayes, R.L.2    DeWitt, D.S.3    Agura, V.4    Faden, A.I.5
  • 64
    • 0023919120 scopus 로고
    • An analogue of thyrotropin-releasing hormone improves outcome after brain injury: 31P-NMR studies
    • McIntosh TK, Vink R, Faden AI (1988) An analogue of thyrotropin-releasing hormone improves outcome after brain injury: 31P-NMR studies. Am J Physiol 254: R 785-792
    • (1988) Am J Physiol , vol.254
    • McIntosh, T.K.1    Vink, R.2    Faden, A.I.3
  • 65
    • 0021067668 scopus 로고
    • Receptors for the excitatory amino acids in the mammalian central nervous system
    • McLennan H (1983) Receptors for the excitatory amino acids in the mammalian central nervous system. Prog Neurobiol 20: 251-271
    • (1983) Prog Neurobiol , vol.20 , pp. 251-271
    • McLennan, H.1
  • 66
    • 0027461725 scopus 로고
    • Did radicals strike Lou Gehrig?
    • McNamara JO, Fridovich I (1993) Did radicals strike Lou Gehrig? Nature 362: 20-21
    • (1993) Nature , vol.362 , pp. 20-21
    • McNamara, J.O.1    Fridovich, I.2
  • 67
    • 0022192856 scopus 로고
    • Effect of pretreatment with the calcium antagonist nimodipine on local cerebral blood flow and histopathology after middle cerebral artery occlusion
    • Mohamed AA, Gotoh O, Graham DI et al. (1985) Effect of pretreatment with the calcium antagonist nimodipine on local cerebral blood flow and histopathology after middle cerebral artery occlusion. Ann Neurol 18: 705-711
    • (1985) Ann Neurol , vol.18 , pp. 705-711
    • Mohamed, A.A.1    Gotoh, O.2    Graham, D.I.3
  • 68
    • 0027414276 scopus 로고
    • Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: A phase II trial
    • Muizelaar JP, Marmarou A, Young HF, Choi SC, Wolf A, Schneider RL, Kontos HA (1993) Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: a phase II trial. J Neurosurg 78: 375-382
    • (1993) J Neurosurg , vol.78 , pp. 375-382
    • Muizelaar, J.P.1    Marmarou, A.2    Young, H.F.3    Choi, S.C.4    Wolf, A.5    Schneider, R.L.6    Kontos, H.A.7
  • 69
    • 0020634826 scopus 로고
    • Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes
    • Muizelaar JP, Wei EP, Kontos HA, Becker DP (1983) Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes. J Neurosurg 59: 822-828
    • (1983) J Neurosurg , vol.59 , pp. 822-828
    • Muizelaar, J.P.1    Wei, E.P.2    Kontos, H.A.3    Becker, D.P.4
  • 70
    • 0022924453 scopus 로고
    • The regulation of cytosolic calcium in rat brain synaptosomes by sodium-dependent calcium efflux
    • Nachshen DA, Sanchez-Armass S, Weinstein AM (1986) The regulation of cytosolic calcium in rat brain synaptosomes by sodium-dependent calcium efflux. J Physiol Lond 381: 17-28
    • (1986) J Physiol Lond , vol.381 , pp. 17-28
    • Nachshen, D.A.1    Sanchez-Armass, S.2    Weinstein, A.M.3
  • 71
    • 0026476704 scopus 로고
    • Morphologic changes in cultured astrocytes after exposure to glutamate
    • Noble U, Hall JJ, Chen S, Chan PH (1992) Morphologic changes in cultured astrocytes after exposure to glutamate. J Neurotrauma 9: 255-267
    • (1992) J Neurotrauma , vol.9 , pp. 255-267
    • Noble, U.1    Hall, J.J.2    Chen, S.3    Chan, P.H.4
  • 72
    • 0023815368 scopus 로고
    • Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery
    • Ohman J, Heiskanen O (1988) Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. J Neurosurg 69 683-686
    • (1988) J Neurosurg , vol.69 , pp. 683-686
    • Ohman, J.1    Heiskanen, O.2
  • 73
    • 0024535031 scopus 로고
    • Protection of rat spinal cord against contusion injury by new prostaglandin derivatives
    • Ohnishi ST, Barr JK, Katagi C, Katsuoka M (1989) Protection of rat spinal cord against contusion injury by new prostaglandin derivatives. Arzneimittelforschung 39: 236-239
    • (1989) Arzneimittelforschung , vol.39 , pp. 236-239
    • Ohnishi, S.T.1    Barr, J.K.2    Katagi, C.3    Katsuoka, M.4
  • 74
    • 0014668762 scopus 로고
    • Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
    • Olney JW (1969) Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science 164: 719-721
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 76
    • 0019970594 scopus 로고
    • Prostacydin and cerebral vessel relaxation
    • Paul KS, Whalley ET, Forster C (1982) Prostacydin and cerebral vessel relaxation. J Neurosurg 57: 334-340
    • (1982) J Neurosurg , vol.57 , pp. 334-340
    • Paul, K.S.1    Whalley, E.T.2    Forster, C.3
  • 77
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates glycolysis: A mechanism coupling neuronal activity to glucose utilization
    • Pellerin L, Magistretti PJ (1994) Glutamate uptake into astrocytes stimulates glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci 91: 10625-10629
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 78
    • 0023927693 scopus 로고
    • Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial
    • Petruk KC, West M, Mohr G et al. (1988) Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial. J Neurosurg 68: 505-517
    • (1988) J Neurosurg , vol.68 , pp. 505-517
    • Petruk, K.C.1    West, M.2    Mohr, G.3
  • 80
    • 0018945258 scopus 로고
    • Prostacyclin, indomethacin and the cerebral circulation
    • Pickard J, Tamura A, Stewart M (1980) Prostacyclin, indomethacin and the cerebral circulation. Brain Res 197: 425-431
    • (1980) Brain Res , vol.197 , pp. 425-431
    • Pickard, J.1    Tamura, A.2    Stewart, M.3
  • 81
    • 0024515530 scopus 로고
    • Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial
    • Pickard JD, Murray GD, Illingworth R et al. (1989) Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. Br Med J 298: 636-642
    • (1989) Br Med J , vol.298 , pp. 636-642
    • Pickard, J.D.1    Murray, G.D.2    Illingworth, R.3
  • 82
    • 0021125414 scopus 로고
    • Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death
    • Rothman S (1984) Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J Neurosci 4: 1884-1891
    • (1984) J Neurosci , vol.4 , pp. 1884-1891
    • Rothman, S.1
  • 83
    • 0021288145 scopus 로고
    • GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage
    • Sabel BA, Slavin MD, Stein DG (1984) GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage. Science 225: 340-342
    • (1984) Science , vol.225 , pp. 340-342
    • Sabel, B.A.1    Slavin, M.D.2    Stein, D.G.3
  • 84
    • 0021921612 scopus 로고
    • A mechanism for glucocorticoid toxicity in the hippocampus: Increased neuronal vulnerability to metabolic insults
    • Sapolsky R (1985) A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults. Science 5: 1227-1231
    • (1985) Science , vol.5 , pp. 1227-1231
    • Sapolsky, R.1
  • 85
    • 0019524246 scopus 로고
    • Steroids in severe head injury. A prospective randomized clinical trial
    • Saul TG, Ducker TB, Salcman M, Carro E (1981) Steroids in severe head injury. A prospective randomized clinical trial. J Neurosurg 54: 596-600
    • (1981) J Neurosurg , vol.54 , pp. 596-600
    • Saul, T.G.1    Ducker, T.B.2    Salcman, M.3    Carro, E.4
  • 89
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment
    • Siesjo BK (1992) Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. J Neurosurg 77: 337-354
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjo, B.K.1
  • 90
    • 0023032788 scopus 로고
    • Perinatal hypoxiaischemia disrupts striatal high affinity glutamate uptake into synaptosomes
    • Silverstein FS, Buchanan K, Johnston MV (1992) Perinatal hypoxiaischemia disrupts striatal high affinity glutamate uptake into synaptosomes. J Neurochem 47: 1614-1619
    • (1992) J Neurochem , vol.47 , pp. 1614-1619
    • Silverstein, F.S.1    Buchanan, K.2    Johnston, M.V.3
  • 92
    • 0000484901 scopus 로고
    • Monitoring and treatment of acute head injury
    • Goris RJA, Trentz O (eds) Spinger, Berlin Heidelberg New York
    • Stocker R, Bemays R, Kossmann T, Imhof H-G (1995) Monitoring and treatment of acute head injury. In: Goris RJA, Trentz O (eds) The integrated approach to trauma care. Spinger, Berlin Heidelberg New York, pp 197-210
    • (1995) The Integrated Approach to Trauma Care , pp. 197-210
    • Stocker, R.1    Bemays, R.2    Kossmann, T.3    Imhof, H.-G.4
  • 93
    • 0023786415 scopus 로고
    • Fluorescence measurement and photochemical manipulation of cytosolic free calcium
    • Tsien RY (1988) Fluorescence measurement and photochemical manipulation of cytosolic free calcium. Trends Neurosci 11: 419-424
    • (1988) Trends Neurosci , vol.11 , pp. 419-424
    • Tsien, R.Y.1
  • 94
    • 0025513852 scopus 로고
    • Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats
    • Vink R, McIntosh TK, Rhomhanyi R, Faden AI (1990) Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats. J Neurosci 10: 3524-3530
    • (1990) J Neurosci , vol.10 , pp. 3524-3530
    • Vink, R.1    McIntosh, T.K.2    Rhomhanyi, R.3    Faden, A.I.4
  • 95
    • 9844261667 scopus 로고
    • Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
    • Volterra A, Trotti O, Floridi S, Racagni G (1994) Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J Neurochem 59: 600-606
    • (1994) J Neurochem , vol.59 , pp. 600-606
    • Volterra, A.1    Trotti, O.2    Floridi, S.3    Racagni, G.4
  • 96
    • 0018874222 scopus 로고
    • Functional, morphological, and metabolic abnormalities of the cerebral micro-circulation after concussive brain injury in cats
    • Wei EP, Dietrich WD, Povlishock JT, Navari RM, Kontos HA (1980) Functional, morphological, and metabolic abnormalities of the cerebral micro-circulation after concussive brain injury in cats. Circ Res 46: 37-47
    • (1980) Circ Res , vol.46 , pp. 37-47
    • Wei, E.P.1    Dietrich, W.D.2    Povlishock, J.T.3    Navari, R.M.4    Kontos, H.A.5
  • 97
    • 0019382872 scopus 로고
    • Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats
    • Wei EP, Kontos HA, Dietrich WD, Povlishock JT, Ellis EF (1981) Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats. Circ Res 48: 95-103
    • (1981) Circ Res , vol.48 , pp. 95-103
    • Wei, E.P.1    Kontos, H.A.2    Dietrich, W.D.3    Povlishock, J.T.4    Ellis, E.F.5
  • 98
    • 0026542967 scopus 로고
    • NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema
    • Westergren I, Johansson BB (1991) NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema. Brain Res 573: 324-326
    • (1991) Brain Res , vol.573 , pp. 324-326
    • Westergren, I.1    Johansson, B.B.2
  • 99
    • 0028009515 scopus 로고
    • Concentrations of amino acids in extracellular fluid after opening of the blood brain barrier by intracarotid infusion of protein sulfate
    • Westergren I, Nystrom B, Hamberger A, Nordborg C, Johannsson BB (1994) Concentrations of amino acids in extracellular fluid after opening of the blood brain barrier by intracarotid infusion of protein sulfate. J Neurochem 62: 159-165
    • (1994) J Neurochem , vol.62 , pp. 159-165
    • Westergren, I.1    Nystrom, B.2    Hamberger, A.3    Nordborg, C.4    Johannsson, B.B.5
  • 100
    • 0027164318 scopus 로고
    • Brain injury and repair mechanisms: The potential for pharmacologic therapy in closed-head trauma
    • White BC, Krause GS (1993) Brain injury and repair mechanisms: the potential for pharmacologic therapy in closed-head trauma. Ann Emerg Med 22 970-979
    • (1993) Ann Emerg Med , vol.22 , pp. 970-979
    • White, B.C.1    Krause, G.S.2
  • 101
    • 0026469070 scopus 로고
    • The diagnosis and initial management of head injury
    • White RJ, Likavec MJ (1992) The diagnosis and initial management of head injury. N Engl J Med 327: 1507-1511
    • (1992) N Engl J Med , vol.327 , pp. 1507-1511
    • White, R.J.1    Likavec, M.J.2
  • 102
    • 0023201281 scopus 로고
    • Pharmacodynamic evaluation of human cerebral arteries in the genesis of vasospasm
    • White RP, Robertson JT (1987) Pharmacodynamic evaluation of human cerebral arteries in the genesis of vasospasm. Neurosurgery 21: 523-531
    • (1987) Neurosurgery , vol.21 , pp. 523-531
    • White, R.P.1    Robertson, J.T.2
  • 103
    • 0021269726 scopus 로고
    • Comparative head trauma experiences in two socioeconomically different Chicago-area communities: A population study
    • Whitman S, Coonley HR, Desai BT (1984) Comparative head trauma experiences in two socioeconomically different Chicago-area communities: a population study. Am J Epidemiol 119: 570-580
    • (1984) Am J Epidemiol , vol.119 , pp. 570-580
    • Whitman, S.1    Coonley, H.R.2    Desai, B.T.3
  • 104
    • 0020040981 scopus 로고
    • Eicosanoids: Prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 polyunsatturated fatty acids
    • Wolfe LS (1982) Eicosanoids: Prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 polyunsatturated fatty acids. J Neurochem 38: 1-14
    • (1982) J Neurochem , vol.38 , pp. 1-14
    • Wolfe, L.S.1
  • 105
    • 0022396925 scopus 로고
    • The role of calcium in spinal cord injury
    • Young W (1985) The role of calcium in spinal cord injury. Cent Nerv Syst Trauma 2: 109-114
    • (1985) Cent Nerv Syst Trauma , vol.2 , pp. 109-114
    • Young, W.1
  • 106
    • 0019960776 scopus 로고
    • Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury
    • Young W, Flamm ES (1982) Effect of high-dose corticosteroid therapy on blood flow, evoked potentials, and extracellular calcium in experimental spinal injury. J Neurosurg 57: 667-673
    • (1982) J Neurosurg , vol.57 , pp. 667-673
    • Young, W.1    Flamm, E.S.2
  • 107
    • 0024561457 scopus 로고
    • Lipid hydroperoxides inhibit reacylation of phospholipids in neuronal membranes
    • Zaleska MM, Wilson DF (1989) Lipid hydroperoxides inhibit reacylation of phospholipids in neuronal membranes. J Neurochem 52 255-260
    • (1989) J Neurochem , vol.52 , pp. 255-260
    • Zaleska, M.M.1    Wilson, D.F.2


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