Dual role of the C34 subunit of RNA polymerase III in transcription initiation

EMBO Journal

Volumn 16, Issue 18, 1997, Pages 5730-5741

  Brun, Isabelle ^a   Sentenac, André ^a   Werner, Michel ^a  

^a CEA SACLAY   (France)

Author keywords

Pre initiation complex; Rna polymerase III; Transcription initiation

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; MUTANT PROTEIN; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE);

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SUBUNIT; GENE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; YEAST;

AMINO ACID SEQUENCE; CELL NUCLEUS; GENES, FUNGAL; KINETICS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLY DA-DT; RNA POLYMERASE III; SACCHAROMYCES CEREVISIAE; TEMPLATES, GENETIC; THERMODYNAMICS; TRANSCRIPTION FACTOR TFIIIB; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0030766849     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.18.5730     Document Type: Article

References (53)

1. Val: homology blocks occur in the vicinity of different tRNA genes. EMBO J., 1, 291-295.
2. Bartel, P., Chien, C.T., Sternglanz, R. and Fields, S. (1993) Elimination of false positives that arise in using the two-hybrid system. Biotechniques, 14, 920-924.
3. Bartholomew, B., Durkovich, D., Kassavetis, G.A. and Geiduschek, E.P. (1993) Orientation and topography of RNA polymerase III in transcription complexes. Mol. Cell. Biol., 13, 942-952.
4. Boeke, J.D., Trueheart, J., Natsoulis, G. and Fink, G.R. (1987) 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol., 154, 164-175.
5. Buratowski, S. and Zhou, H. (1992) A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIB. Cell, 71, 221-230.
6. Buratowski, S., Hahn, S., Guarente, L. and Sharp, P.A. (1989) Five intermediate complexes in transcription initiation by RNA polymerase II. Cell, 56, 549-561.
7. Burnol, A.-F., Margottin, F., Huet, J., Almouzni, G., Prioleau, M.-N., Méchali, M. and Sentenac, A. (1993) TFIIIC relieves repression of U6 snRNA transcription by chromatin. Nature, 362, 475-477.
8. Bushnell, D.A., Bamdad, C. and Kornberg, R.D. (1996) A minimal set of RNA polymerase II transcription protein interactions. J. Biol. Chem., 271, 20170-20174.
9. Camier, S., Dechampesme, A.-M. and Sentenac, A. (1995) The only function of TFIIIA in yeast is the transcription of 5S rRNA genes. Proc. Natl Acad. Sci. USA, 92, 9338-9342.
10. Chaussivert, N., Conesa, C., Shaaban, S. and Sentenac, A. (1995) Complex interactions between yeast TFIIIB and TFIIIC. J. Biol. Chem., 270, 15353-15358.
11. Chiannilkulchai, N., Stalder, R., Riva, M. Carles, C., Werner, M. and Sentenac, A. (1992) RPC82 encodes the highly conserved, third largest subunit of RNA polymerase C (III) from Saccharomyces cerevisiae. Mol. Cell. Biol., 12, 4433-4440.
12. Colbert, T. and Hahn, S. (1992) A yeast TFIIB-related factor involved in RNA polymerase III transcription. Genes Dev., 6, 1940-1949.
13. Comai, L., Zomerdijk, J.C.B.M., Beckmann, H., Zhou, S., Admon, A. and Tjian, R. (1994) Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. Science, 266, 1966-1972.
14. Dieci, G., Hermann-Le Denmat, S., Lukhtanov, E., Thuriaux, P., Werner, M. and Sentenac, A. (1995) A universally conserved region of the largest subunit participates in the active site of RNA polymerase III. EMBO J., 14, 3766-3776.
15. Dieci, G. and Sentenac, A. (1996) Facilitated recycling pathway for RNA polymerase III. Cell, 84, 245-252.
16. Flores, O., Lu, H., Killeen, M., Greenblatt, J., Burton, Z.F. and Reinberg, D. (1991) The small subunit of transcription factor IIF recruits RNA polymerase II into the pre-initiation complex. Proc. Natl Acad. Sci. USA, 88, 9999-10003.
17. Gudenus, R., Mariotte, S., Moenne, A., Ruet, A., Memet, S., Buhler, J.-M., Sentenac, A. and Thuriaux, P. (1988) Conditional mutants of RPC160, the gene encoding the largest subunit of RNA polymerase C in Saccharomyces cerevisiae. Genetics, 119, 517-526.
18. Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K. and Elledge, S.J. (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75, 805-816.
19. Hausner, W. and Thomm, M. (1995) The translation product of the presumptive Thermococcus celer TATA-binding protein sequence is a transcription factor related in structure and function to Methanococcus transcription factor B. J. Biol. Chem., 270, 17649-17651.
20. Hermann-Le Denmat, S., Werner, M., Sentenac, A. and Thuriaux, P. (1994) Suppression of yeast RNA polymerase III mutations by FHL1, a gene coding for a fork head protein involved in rRNA processing. Mol. Cell. Biol., 14, 2905-2913.
21. Huet, J. and Sentenac, A. (1992) The TATA-binding protein participates in TFIIIB assembly on tRNA genes. Nucleic Acids Res., 20, 6451-6454.
22. Huet, J., Riva, M., Sentenac, A. and Fromageot, P. (1985) Yeast RNA polymerase C and its subunits: specific antibodies as structural and functional probes. J. Biol. Chem., 260, 15304-15310.
23. 70 affects formation, stability and function of pre-initiation complexes. J. Biol. Chem., in press.
24. Kassavetis, G.A., Braun, B.R., Nguyen, L.H. and Geiduschek, E.P. (1990) S.cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors. Cell, 60, 247-257.
25. Kassavetis, G.A., Blanco, J.A., Johnson, T.E. and Geiduscheck, E.P. (1992a) Formation of open and elongating transcription complexes by RNA polymerase III. J. Mol. Biol., 226, 47-58.
26. Kassavetis, G.A., Joazeiro, C.A.P., Pisano, M., Geiduschek, E.P., Colbert, T., Hahn, S. and Blanco, J.A. (1992b) The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB. Cell, 71, 1055-1064.
27. Kassavetis, G.A., Nguyen, S.T., Kobayashi, R., Kumar, A., Geiduschek, E.P. and Pisano, M. (1995) Cloning, expression, and function of TFC5, the gene encoding the B″ component of the Saccharomyces cerevisiae RNA polymerase III transcription factor TFIIIB. Proc. Natl Acad. Sci. USA, 92, 9786-9790.
28. Keys, D.A., Vu, L., Steffan, J.S., Dodd, J.A., Yamamoto, R.T., Nogi, Y. and Nomura, M. (1994) RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae. Genes Dev., 8, 2349-2362.
29. Khoo, B., Brophy, B. and Jackson, S.P. (1994) Conserved functional domains of the RNA polymerase III general transcription factor BRF. Genes Dev., 8, 2879-2890.
30. Killeen, M., Coulombe, B. and Greenblatt, J. (1992) Recombinant TBP, transcription factor IIB, and RAP30 are sufficient for promoter recognition by mammalian RNA polymerase II. J. Biol. Chem., 267, 9463-9466.
31. Kunkel, T.D., Roberts, J.D. and Zakour, R.A. (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol., 154, 367-382.
32. Lalo, D., Steffan, J.S., Dodd, J.A. and Nomura, M. (1996) RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I. J. Biol. Chem., 271, 21062-21067.
33. López-De-León, A., Librizzi, M., Puglia, K. and Willis, I.M. (1992) PCF4 encodes an RNA polymerase III transcription factor with homology to TFIIB. Cell, 71, 211-220.
34. Maxam, A.M. and Gilbert, W. (1980) Sequencing end-labeled DNA with base-specific chemical cleavage. Methods Enzymol., 65, 499-560.
35. Mosrin, C., Riva, M., Beltrame, M., Cassar, E., Sentenac, A. and Thuriaux, P. (1990) The RPC31 gene of Saccharomyces cerevisiae encodes a subunit of RNA polymerase C (III) with an acidic tail. Mol. Cell. Biol., 10, 4737-4743.
36. Persinger, J. and Bartholomew, B. (1996) Mapping the contacts of yeast TFIIIB and RNA polymerase III at various distances from the major groove of DNA by DNA photoaffinity labeling. J. Biol. Chem., 271, 33039-33046.
37. Qureshi, S.A., Khoo, B. and Jackson, S.P. (1995) Molecular cloning of the transcription factor TFIIB homolog from Sulfolobus shibatae. Proc. Natl Acad. Sci. USA, 92, 6077-6081.
38. Roberts, S., Miller, S.J., Lane, W.S., Lee, S. and Hahn, S. (1996) Cloning and functional characterization of the gene encoding the TFIIIB90 subunit of RNA polymerase III transcription. J. Biol. Chem., 271, 14903-14909.
39. Rüth, J., Conesa, C., Dieci, G., Lefebvre, O., Düsterhöft, A., Ottonello, S. and Sentenac, A. (1996) A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB. EMBO J., 15, 1941-1949.
40. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
41. Sherman, F. (1991) Getting started with yeast. Methods Enzymol., 194, 3-21.
42. Stettler, S., Mariotte, S., Riva, M., Sentenac, A. and Thuriaux, P. (1992) An essential specific subunit of RNA polymerase III (C) is encoded by gene RPC34 in Saccharomyces cerevisiae. J. Biol. Chem., 267, 21390-21395.
43. Struhl, K. (1995) Yeast transcriptional mechanisms. Annu. Rev. Genet., 29, 651-674.
44. Tan, S., Pfeil Garrett, K., Conaway, R.C. and Conaway, J.W. (1994) Cryptic DNA-binding domain in the C-terminus of RNA polymerase II general transcription factor RAP30. Proc. Natl Acad. Sci. USA, 91, 9808-9812.
45. Thuillier, V., Stettler, S., Sentenac, A., Thuriaux, P. and Werner, M. (1995) A mutation in the C31 subunit of Saccharomyces cerevisiae RNA polymerase III affects transcription initiation. EMBO J., 14, 351-359.
46. Thuillier, V., Brun, I., Sentenac, A. and Werner, M. (1996) Mutations in the α-amanitin conserved domain of the largest subunit of yeast RNA polymerase III affect pausing, RNA cleavage and transcriptional transitions. EMBO J., 15, 618-629.
47. Wang, Z. and Roeder, R.G. (1995) Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB-and high-mobility-group protein 2-related domains. Proc. Natl Acad. Sci. USA, 92, 7026-7030.
48. Wang, Z. and Roeder, R.G. (1997) Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation. Genes Dev., 10, 1315-1326.
49. Werner, M., Hermann-Le Denmat, S., Treich, I., Sentenac, A. and Thuriaux, P. (1992) Effect of mutations in a zinc binding domain of yeast RNA polymerase C (III) on enzyme function and subunit association. Mol. Cell. Biol., 12, 1087-1095.
50. Werner, M., Chaussivert, N., Willis, I.M. and Sentenac, A. (1993) Interaction between a complex of RNA polymerase III subunits and the 70 kDa component of TFIIIB. J. Biol. Chem., 268, 20721-20724.
51. Wertman, K.F., Drubin, D.G. and Botstein, D. (1992) Systematic mutational analysis of the yeast ACT1 gene. Genetics, 132, 337-350.
52. White, R.J. (1994) RNA Polymerase III Transcription. R.G. Landes Company, Austin, TX.
53. Yamamoto, R.T., Nogi, Y., Dodd, J.A. and Nomura, M. (1996) RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template. EMBO J., 15, 3964-3973.