Immunological response to repeated administration of recombinant human erythropoietin in rats: Biphasic effect on its pharmacokinetics

Drug Metabolism and Disposition

Volumn 25, Issue 9, 1997, Pages 1039-1044

  Kato, Motohiro ^b   Miura, Kumi ^b   Kamiyama, Hiroshi ^b   Okazaki, Akira ^b   Kumaki, Kenji ^b   Kato, Yukio ^b   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DRUG ANTIBODY; IODINE 125; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; DRUG ANTIGENICITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG PROTEIN BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTIBODIES; ANTIGEN-ANTIBODY COMPLEX; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; EPOETIN ALFA; HALF-LIFE; HUMANS; MALE; METABOLIC CLEARANCE RATE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030766422     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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