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Volumn 36, Issue 16, 1997, Pages 1674-1694

Chemistry and Molecular Biology of Transmissible Spongiform Encephalopathies

Author keywords

Creutzfeldt Jakob disease; Gene technology; Prion protein; Protein structures; Protein only hypothesis

Indexed keywords


EID: 0030766271     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199716741     Document Type: Review
Times cited : (20)

References (152)
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    • note
    • This phenomenon is known from viral pathogens: the pathology changes because of mutations in the viral genome, but the principal infectivity remains.
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    • H. Diringer in Spongiforme Encephalopathien bei Tieren unter besonderer Berücksichtigung der BSE. Band 75 (Ed.: W. Köhler). Deutsche Akademie der Naturforscher Leopoldina, Halle, 1996, pp. 26-28. Diringer also commented on his hypothesis in a round table discussion at the Deutsche Akademie der Naturforscher Leopoldina, moderated by Prof. Rudolf Rott.
    • (1996) Spongiforme Encephalopathien Bei Tieren Unter Besonderer Berücksichtigung der BSE , vol.75 , pp. 26-28
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    • "Prion" is a slight modification of the abbreviation "Proin"
    • "Prion" is a slight modification of the abbreviation "Proin".
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    • note
    • Sc.
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    • note
    • First reports on a putative case of scrapie in cattle go back to the 19th century [151].
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    • R. G. Will, J. W. Ironside, M. Zeidler, S. N. Cousens, K. Estibeiro, A. Alperovitch, S. Poser, M. Pocchiari, A. Hofman, P. G. Smith, Lancet 1996, 347, 921-925; this publication had ramifications beyond its scientific significance (the article was the most-cited scientific publication in 1996; source: Institute for Scientific Information, Hot Papers Database, November/December 1994-November/December 1996) - it also had political effects: in spring 1996 the British government was forced to admit for the first time that a transmission of BSE to humans cannot be excluded. At European level, the commission of the European Union introduced an export ban for British beef.
    • (1996) Lancet , vol.347 , pp. 921-925
    • Will, R.G.1    Ironside, J.W.2    Zeidler, M.3    Cousens, S.N.4    Estibeiro, K.5    Alperovitch, A.6    Poser, S.7    Pocchiari, M.8    Hofman, A.9    Smith, P.G.10
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    • R. John Ellis also pictorially calls this container an "Anfinsen cage" [152]
    • R. John Ellis also pictorially calls this container an "Anfinsen cage" [152].
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    • note
    • This statement is valid at least in the limited sense of Prusiner's heterodimer model.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.