A postsynaptic excitatory amino acid transporter with chloride conductance functionally regulated by neuronal activity in cerebellar Purkinje cells

Journal of Neuroscience

Volumn 17, Issue 18, 1997, Pages 7017-7024

  Kataoka, Yosky ^a,b   Morii, Hiroshi ^a,c   Watanabe, Yasuyoshi ^a,c   Ohmori, Harunori ^b  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Arachidonate; Chloride conductance; Excitatory amino acid; Patch clamp; Phospholipase A2; Postsynaptic transporter; Purkinje cell

Indexed keywords

ARACHIDONIC ACID; CALCIUM ION; CHLORIDE ION; EXCITATORY AMINO ACID; NEUROTRANSMITTER; PHOSPHOLIPASE A2; POSTSYNAPTIC RECEPTOR;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; DENDRITE; DEPOLARIZATION; FACILITATION; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; PERIKARYON; PRIORITY JOURNAL; PURKINJE CELL; RAT; SYNAPTIC TRANSMISSION;

EID: 0030766256     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-18-07017.1997     Document Type: Article

References (19)

1. Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-5569.
2. Barbour B, Brew H, Attwell D (1988) Electrogenic glutamate uptake in glial cells is activated by intracellular potassium. Nature 335:433-435.
3. Barbour B, Szatkowski M, Ingledew N, Attwell D (1989) Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 342:918-920.
4. Barbour B, Brew H, Attwell D (1991) Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina. J Physiol (Lond) 436:169-193.
5. Barbour B, Keller BU, Llano I, Marty A (1994) Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells. Neuron 12:1331-1343.
6. Billups B, Rossi D, Attwell D (1996) Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells. J Neurosci 16:6722-6731.
7. Blobe GC, Khan WA, Hannun YA (1995) Protein kinase C: cellular target of the second messenger arachidonic acid? Prostaglandins Leukot Essent Fatty Acids 52:129-135.
8. Brew H, Attwell D (1987) Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature 327:707-709.
9. +)-ATPase activity in brain slices and synaptosomes by arachidonic acid. J Neurochem 40:309-316.
10. 2+-dependent translocation domain with homology to PKC and GAP. Cell 65:1043-1051.
11. Eliasof S, Jahr CE (1996) Retinal glial cell glutamate transporter is coupled to an anionic conductance. Proc Natl Acad Sci USA 93:4153-4158.
12. Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375:599-603.
13. Hagiwara S, Ohmori H (1982) Studies of calcium channels in rat clonal pituitary cells with patch electrode voltage clamp. J Physiol (Lond) 331:231-252.
14. Hirano T, Kubo Y, Wu MM (1986) Cerebellar granule cells in culture: monosynaptic connections with Purkinje cells and ionic currents. Proc Natl Acad Sci USA 83:4957-4961.
15. Kanai Y, Hediger MA (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360:467-471.
16. Kanai Y, Smith CP, Hediger MA (1993) The elusive transporters with a high affinity for glutamate. Trends Neurosci 16:365-370.
17. Kanai Y, Nussberger S, Romero MF, Boron WF, Hebert SC, Hediger MA (1995) Electrogenic properties of the epithelial and neuronal high affinity glutamate transporter. J Biol Chem 270:16561-16568.
18. Kataoka Y, Ohmori H (1996) Of known neurotransmitters, glutamate is the most likely to be released from chick cochlear hair cells. J Neurophysiol 76:1870-1879.
19. Kataoka Y, Ohmori H, Kataoka K (1995) Postsynaptic uptake of excitatory amino acids in rat cerebellar Purkinje cells. Soc Neurosci Abstr 21:1859.