Graft ischemia correlates with urinary excretion of the proximal marker enzyme fructose-1,6-bisphosphatase in human kidney transplantation

Nephron

Volumn 77, Issue 1, 1997, Pages 62-67

  Kotanko, Peter ^a   Margreiter, Raimund ^a   Pfaller, Walter ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

6 bisphosphatase; Cold ischemia time; Fructose 1; Graft storage; Ischemia; N acetyl D glucosaminidase; Renal transplantation; Urinary enzymes

Indexed keywords

CREATININE; FRUCTOSE BISPHOSPHATASE; MARKER; N ACETYL BETA GLUCOSAMINIDASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CREATININE URINE LEVEL; DISEASE SEVERITY; ENZYMURIA; FEMALE; GRAFT PRESERVATION; HUMAN; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; KIDNEY TRANSPLANTATION; KIDNEY TUBULE DAMAGE; MALE; MULTIPLE REGRESSION; PRIORITY JOURNAL; TIME; URINARY EXCRETION;

EID: 0030765102     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000190248     Document Type: Article

References (20)

1. Goren MP, Wright RK, Osborne S: Two automated procedures for N-acetyl-β-D-glucosam-inidase determination evaluated for detection of drug-induced tubular nephrotoxicity. Clin Chem 1986:32:2052-2055.
2. Price RG, Whiting PH: Urinary enzymes and nephrotoxicity in humans; in Jung K. Malten-heimer H. Burchardt U (eds): Urinary Enzymes in Clinical and Experimental Medicine. Berlin, Springer. 1992, pp 203-221.
3. Hofer E, Kotanko P: Urinary NAG excretion after controlled hypotension in humans: Lubec G, Campese V (eds): in Advances in Non-Invasive Nephrology. London. Libbey, 1987, pp 236-240.
4. Kehrer G, Blech M, Kallerhoff M, Bretschnei-der HJ: Urinary LDH-release for evaluation of postischemic renal function. Klin Wochenschr 1989;67:477-485.
5. Asfar SK, Whiting PH, Simpson JG, Catto GR, Engeset J: Early diagnosis of rejection. Correlation of enzymuria and histological findings after renal transplantation in the rat. Transplantation 1984:37:548-551.
6. Sri Krishna K, Kirubakaran MG, Pandey AP, Kanagasabapathy AS: Urinary N-acetyl-β-D-glucosaminidase and aminopeptidase N in the diagnosis of graft rejection after live donor renal transplantation. Clin Chim Acta 1985; 150:69-85.
7. Jung K, Mattenheimer H, Burchardt U (eds): Urinary Enzymes in Clinical and Experimental Medicine. Berlin. Springer. 1992.
8. Jung K, Kotanko P: Urinary enzymes in kidney transplantation: in Jung K, Mattenheimer H, Burchardt U (eds): Urinary Enzymes in Clinical and Experimental Medicine. Berlin. Springer. 1992. pp 189-202.
9. Margreiter R, Fuchs D, Hausen A, Huber C, Reibnegger G, Spielberger M, Wächter H: Neopterin as a new biochemical marker for diagnosis of allograft rejection. Transplantation 1983:36:650-653.
10. Maruhn D, Strozyk K, Giclow L. Bock KD: Diurnal variations of urinary enzyme excretion. Clin Chim Acta 1977;75:427-433.
11. Latzko E, Gibbs M: ‘Alkalische’ Cl-Fruktose-1.6-diphosphatasc: in Bergmeyer H. Methoden der enzymatischen Analyse. Weinheim. Verlag Chemie. 1974. pp 914-917.
12. Maruhn D: Rapid colorimetric assay of β-gal-actosidase and N-acetyl- β -D-glucosam inidase in human urine. Clin Chim Acta 1976:73:453- 461.
13. Jung K, Schulze G, Reinholdt C: Different diuresis dependent excretion of urinary enzymes: N-Acetyl-β-D-glucosaminidase, alanine aminopeptidase, alkaline phosphatase, and gamma-glutamyltransferase. Clin Chem 1986: 32:529-532.
14. Siegel S, Castellan NJ Jr: Nonparametric Statistics for Behavioral Sciences. New York. McGraw-Hill, 1988. pp 235-244.
15. Lellir M, Dubach UC, Guder WJ: Distribution of acid hydrolases in the nephron of normal and diabetic rats. Int J Biochem 1980;12:41-45.
16. Burch HB, Narins RG, Chu C, Fagioli S, Choi S, McCarthy W, Lowry OH: Distribution along the rat nephron of three enzymes of gluconeo-genesis in acidosis and starvation. Am J Physiol 1978;235:F246-F253.
17. Pfaller W, Thorwartl U, Nevinny-Stickel M, Krall M, Schober M, Joannidis M, Hobisch A: Clinical value of fructose 1,6-bisphosphatase in monitoring renal proximal tubular injury. Kidney Int 1994:46(suppl 47):68-75.
18. Schmid H, Mall A, Bockhom H: Specific fructose-1.6-bisphosphatase activities in microdissected proximal tubules of human kidneys: in function and dysfunction; in Kovacevic Z, Guder WG (eds): Molecular Nephrology. Biochemical Aspects of Kidney Function. Berlin. De Gruyter, 1987. pp 339-345.
19. Olsen S, Burdick JF, Keown PA, Wallace AC, Racusen LC, Solez K TI: Primary acute renal failure (‘acute tubular necrosis’) in the transplanted kidney: Morphology and pathogenesis. Medicine 1989;68:173-187.
20. Dawidson I, Ar’Rajab A, Dickerman R, Husberg B, Klintmalm G, Lu C, Melone D, Rem-mich S, Risser R, Trevino G, Wallace J: Perioperative albumin and verapamil improve early outcome after cadaver renal transplantation. Transplant Proc 1994:26:3100-3101.