Chronic infection in the etiology of atherosclerosis the case for Chlamydia pneumoniae

Clinical Cardiology

Volumn 20, Issue 10, 1997, Pages 829-836

  Gupta, Sandeep ^a   Camm, A John ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Atherosclerosis; Chlamydia pneumoniae; Coronary heart disease

Indexed keywords

ROXITHROMYCIN;

ANTIBIOTIC THERAPY; ATHEROSCLEROSIS; BACTERIUM IDENTIFICATION; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CHRONICITY; CORONARY RISK; DISEASE ASSOCIATION; HUMAN; PATHOGENESIS; REVIEW;

EID: 0030764926     PISSN: 01609289     EISSN: None     Source Type: Journal    
DOI: 10.1002/clc.4960201008     Document Type: Review

References (68)

1. Solberg LA, Enger SC, Hjermann I, Helgeland A, Holme I, Leren P, Strong JP: Risk factors for coronary and cerebral atherosclerosis in the Oslo Study. In Atherosclerosis V (Eds. Gotto AM, Smith LC, Allen B), p. 57-62. New York, N.Y.: Springer-Verlag, 1980
2. Ross R: The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-809
3. Reidy MA, Bowyer DE: Distortion of endothelial repair. The effect of hypercholesterolaemia on regulation of aortic endothelium following injury by endotoxin. A scanning microscopy study. Atherosclerosis 1978;29:459-466
4. Pesonen E, Kaprio E, Rapola J, Soveri T, Oksanen H: Endothelial cell damage in piglet coronary artery after administration of E.coli endotoxin. A scanning and transmission electron microscopic study. Atherosclerosis 1981;40:65-73
5. Hansson GK: Immune mechanisms in atherosclerosis. Atherosclerosis 1989;9:567-568
6. Hajjar DP, Falcone DJ, Fabricant CG, Fabricant J: Altered cholesteryl ester cycle is associated with lipid accumulation in herpesvirus-infected arterial smooth muscle cells. J Biol Chem 1985;260: 6124-6128
7. Leatham EW, Bath PM, Tooze JA, Camm AJ: Increased monocyte tissue factor expression in coronary disease. Br Heart J 1995;73: 10-13
8. Visser MR, Tracey PB, Vercellotti GM, Goodman JL, White JG, Jacob HS: Enhanced thrombin generation and platelet binding on herpes simplex virus-infected endothelium. Proc Natl Acad Sci USA 1988;85:8227-8230
9. Fabricant CG, Fabricant J, Litrenta MM, Minick CR: Virus-induced atherosclerosis. J Exp Med 1978;148:335-340
10. Fabricant CG, Fabricant J, Minick CR, Litrenta MM: Herpesvirus-induced atherosclerosis in chickens. Fed Proc 1983;42:2467-2469
11. Melnick JL, Petrie BL, Dreesman GR, Burek J, McCollum CH, DeBakey ME: Cytomegalovirus antigen within human arterial smooth muscle cells. Lancet 1983;2:644-647
12. Speir E, Modali R, Huang ES, Leon MB, Shawl F, Finkel T, Epstein SE: Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 1994;265:391-394
13. Zhou YF, Leon MB, Waclawiw MA, Popma JJ, Yu ZX, Finkel T, Epstein SE: Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy. N Engl J Med 1996;335:624-630
14. Sorlie PD, Adam E, Melnick JL, Folsom A, Skelton T, Chambless LE, Barnes R, Melniek JL: Cytomegalovirus/herpesvirus and carotid atherosclerosis: The ARIC study. J Med Virol 1994;42:33-37
15. Kol A, Sperti G, Shani J, Schulhoff N, van de Greet W, Landini MP, Laplace M, Maseri A, Crea F: Cytomegalovirus replication is not a cause of instability in unstable angina. Circulation 1995;91: 1910-1913
16. Johnson DE, Gao SZ, Schroeder JS, Hunt S, Alderman EL, Stinson E: The spectrum of coronary artery pathologic findings in human cardiac allografts. J Heart Transplant 1989;8:349-359
17. Grattan MT: Accelerated graft atherosclerosis following cardiac transplantation: Clinical perspectives. Clin Cardiol 1991;14(suppl II):16-20
18. McDonald K, Rector TS, Braunlin EA, Kubo SH, Olivari MT: Association of coronary artery disease in cardiac transplant recipients with cytomegalovirus infection. Am J Cardiol 1989;64: 359-362
19. Marchant B, Ranjadayalan K, Stevenson R, Wilkinson P, Timmis AD: Circadian and seasonal factors in the pathogenesis of acute myocardial infarction: The influence of environmental temperature. Br Heart J 1993;69:385-387
20. Enquselassie F, Dobson AJ, Alexander HM, Steele PL: Seasons, temperature and coronary disease. Int J Epidemiol 1993;22: 632-636
21. Housworth J, Langmuir AD: Excess mortality from epidemic influenza, 1957-1966. Am J Epidemiol 1974;100:40-48
22. Spodick DH, Flessas AP, Johnson MM: Association of acute respiratory symptoms with onset of acute myocardial infarction: Prospective investigation of 150 consecutive patients and matched controls. Am J Cardiol 1984;53:481-482
23. Woodhouse PR, Khaw KT, Plummer M, Foley A, Meade TW: Seasonal variations of plasma fibrinogen and factor VIIa activity in the elderly: Winter infections and deaths from cardiovascular disease. Lancet 1994;343:435-439
24. Mendall MA, Goggin P, Molineaux N, Levy J, Toosy T, Strachan DP, Northfield TC: Association between childhood living conditions and Helicobacter seropositivity in adult life. Lancet 1992;i: 896-897
25. Langman M, Cooke A: Gastric and duodenal ulcer and their associated diseases. Lancet 1976;i:680-683
26. Mendall MA, Goggin PM, Molineaux N, Strachan DP, Camm AJ, Northfield TC: Relation of Helicobacter pylori infection and coronary heart disease. Br Heart J 1994;71:437-439
27. Martin-de-Argila C, Boixeda D, Canton R, Gisbert J, Fuertes A: High seroprevalence of Helicobacter pylori infection in coronary heart disease (letter). Lancet 1995;346:310
28. Patel P, Mendall MA, Carrington D, Strachan DP, Leatham EW, Molineaux N, Levy J, Blakeston C, Seymour CA, Camm AJ, Northfield TC: Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors. Br Med J 1995;311:711-714
29. Parente F, Maconi G, Imbesi V, Sangaletti O, Poggio M, Rossi E, Piergiorgio D, Porro GB: Helicobacter pylori infection and coagulation in healthy people. Br Med J 1997;314:1318-1319
30. Murray LJ, Bamford KB, O'Reilly DP, McCrum EE, Evans AE: Helicobacter pylori infection: Relation with cardiovascular risk factors, ischaemic heart disease, and social class. Br Heart J 1995; 74:497-501
31. Whincup PH, Mendall MA, Perry IJ, Strachan DP, Walker M: Prospective relations between Helicobacter pylori infection, coronary heart disease and stroke in middle aged men. Heart 1996;75: 568-572
32. Sandifer QD, Vuilo S, Crompton G: Association of Helicobacter pylori infection with coronary heart disease: Association may not be causal (letter). Br Med J 1996;312:251
33. Blasi F, Denti F, Erba M, Cosentini R, Raccanelli R, Rinaldi A, Fagetti L, Esposito G, Ruberti U, Allegra L: Detection of Chlamydia pneumoniae but not Helicobacter pylori in atherosclerotic plaques of aortic aneurysms. J Clin Microbiol 1996;34:2766-2769
34. Paunio K, Impivaara O, Tickso J, Maki J: Missing teeth and ischaemic heart disease in men aged 45-64 years. Eur Heart J 1993; 14(suppl K):S54-S56
35. Grayston JT, Kuo C-C, Campbell LA, Wang SP: Chlamydia pneumoniae sp. nov. for Chlamydia, strain TWAR. Int J Syst Bacteriol 1989;39:88-90
36. Saikku P: The epidemiology and significance of Chlamvdia pneumoniae. J Infect 1992;1:27-34
37. Grayston JT, Wang S-P, Kuo C-C, Campbell LA: Current knowledge on Chlamydia pneumoniae, strain TWAR, an important cause of pneumonia and other acute respiratory diseases. Eur J Clin Microbiol Infect Dis 1989;8:191-202
38. Kuo C-C, Shor A, Campbell LA, Fukushi H, Patton DL, Grayston JT: Demonstration of Chlamydia pneumoniae in atherosclerotic lesions of coronary arteries. J Infect Dis 1993;167:841-849
39. Leinonen M, Linnanmaki E, Manila K, Nieminan MS, Valtonen V, Leirisalo-Repo M, Saikku P: Circulating immune complexes containing chlamydial lipopolysaccharide in acute myocardial infarction. Microbiol Pathog 1990;9:67-73
40. Mendall MA, Carrington D, Strachan DP, Patel P, Molineaux N, Levy J, Toosey T, Camm AJ, Northfield TC: Chlamydia pneumoniae: Risk factors for seropositivity and association with coronary heart disease: J Infect 1995;30:121-128
41. Thom DH, Grayston JT, Siscovick DS, Wang SP, Weiss NS, Daling JR: Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease. J Am Med Assoc 1992;268:68-72
42. Saikku P, Leinonen M, Mattila K, Ekman MR, Nieminen MS, Makela PH, Huttenen JK, Valtonen V: Serological evidence of an association of a novel chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 1988;2: 983-986
43. Melnick SL, Shahar E, Folsom AR, Grayston JT, Sorlie PD, Wang SP, Szklo M: Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Am J Med 1993;95:499-504
44. Thom DH, Wang S-P, Grayston JT, Siscovick DS, Stewart DK, Kronmal RA, Weiss NS: Chlamydia pneumoniae strain TWAR antibody and angiographically demonstrated coronary artery disease. Arterioscler Thromb 1991;11:547-551
45. Haidl S, Juul-Möller S, Israelsson B, Persson K: Ischaemic heart disease and antibodies to Chlamydia pneumoniae (TWAR) (abstr). Proc Eur Soc Chlam Res 1992;2:174
46. Cook PJ, Lip GY, Zarifis J, Honeybourne D, Wise R, Beevers DG: Is Chlamydia pneumoniae infection associated with acute cardiac ischaemic syndromes? (abstr). J Am Coll Cardiol 1996;324(suppl A):807-812
47. Saikku P, Leinonen M, Tenkanen L, Linnanmaki E, Ekman MR, Manninen V, Mantarri M, Frick MH: Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study. Ann Intern Med 1992;116:273-278
48. Holt PG: Immune and inflammatory function in smokers. Thorax 1987;42:241-249
49. Hahn DL, Golubjatnikov R: Smoking is a potential confounder of the Chlamydia pneumoniae-coronary artery disease association. Arterioscler Thromb 1992;12:255-260
50. Cook PJ, Honeybourne D, Lip GY, Beevers DG, Wise R: Chlamydia pneumoniae and acute arterial thrombotic disease. Circulation 1995;92:3148-3149
51. Aceti A, Mazzacurati G, Amendolea M, Pennica A, Zechini B, Trappolini M, Puletti M: Relation of C reactive protein to cardiovascular risk factors: Helicobacter pylori and Chlamydia pneumoniae infections may account for most acute coronary syndromes. Br Med J 1996;313:428-429
52. Campbell LA, O'Brien ER, Cappuccio AL, Kuo CC, Wang SP, Stewart D, Patton DL, Cummings PK, Grayston JT: Detection of Chlamydia pneumoniae TWAR in human coronary atherectomy tissues. J Infect Dis 1995;172:585-588
53. Ong G, Thomas BJ, Mansfield AO, Davidson BR, Taylor Robinson D: Detection and widespread distribution of Chlamydia pneumoniae in the vascular system and its possible implications. J Clin Path 1996;49:102-106
54. Grayston JT, Kuo C-C, Coulson AS, Campbell LA, Lawrence RD, Lee MJ, Strandness ED, Wang SP: Chlamydia pneumoniae (TWAR) in atherosclerosis of the carotid artery. Circulation 1995;92:3397-3400
55. Muhlestein JB, Hammond EH, Carlquist JF, Radicke E, Thomson MJ, Karagounis LA, Woods ML, Anderson JL: Increased incidence of Chlamydia species within the coronary arteries of patients with symptomatic atherosclerotic versus other forms of cardiovascular disease. J Am Coll Cardiol 1996;27:1555-1561
56. Gaydos CA, Summersgill JT, Sahney NN, Ramirez JA, Quinn TC: Replication of Chiamydia pneumoniae in vitro in human macrophages, endothelial cells, and aortic artery smooth muscle cells. Infect Immunol 1996;64:1614-1620
57. Ramirez JA: Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis. The Chlamydia pneumoniae Atherosclerosis Study Group. Ann Intern Med 1996;125:979-982
58. Laitinen K, Saikku P: Chlamydia pneumoniae induced atherosclerosis in rabbits (abstr). Proceedings of the International Symposium of the Immunopathogenesis of Chlamydial Infections 1996;4:196
59. Holland MJ, Bailey RL, Hayes LJ, Whittle HC, Mabey DC: Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens. J Infect Dis 1993; 168:1528-1531
60. Kaukoranta-Tolvanen SS, Teppo AM, Laitinen K, Saikku P, Linnavuori K, Leinonen M: Growth of Chlamydia pneumoniae in cultured human peripheral blood mononuclear cells and induction of a cytokine response. Microbiol Pathog 1996;21:215-221
61. Patel P, Carrington D, Strachan DP, Goggin P, Leatham EW, Northfield TC, Mendall MA: Fibrinogen: A link between chronic infection and coronary heart disease. Lancet 1994;343:1634-1635
62. Mendall MA, Patel P, Ballam L, Strachan D, Northfield TC: C reactive protein and its relation to cardiovascular risk factors: A population based cross sectional study. Br Med J 1996;312:1061-1065
63. Morrison RP, Belland RJ, Lyng K, Caldwell HD: Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein. J Exp Med 1989;170:1271-1283
64. Xu Q, Willeit J, Marosi M, Kleindienst R, Oberhollenzer F, Kiechl S, Stulnig T, Luef G, Wick G: Association of serum antibodies to heat shock protein 65 with carotid atherosclerosis. Lancet 1993; 341:255-259
65. Gupta S, Leatham EW, Carrington D, Mendall MA. Ireson N, Tooze J, Bevan D, Camm AJ, Kaski JC: The effect of azithromycin in post myocardial infarction patients with elevated Chlamydia pneumoniae antibody titres (abstr). J Am Coll Cardiol 1997; 755:209
66. Gupta S, Leatham EW, Carrington D, Mendall MA, Kaski JC, Camm AJ: Elevated Chlamydia penumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. Circulation 1997;96:404-407
67. Gurfinkel E, Bozovich G, Darococa A, Beek E, Mautner B: Randomized trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS pilot study. Lancet 1997;350:404-407
68. Gupta S, Camm AJ. Chlamydia pneumoniae and coronary heart disease. Br Med J 1997;314:1778-1779