Demonstration of L-dopa decarboxylating neurons specific to human striatum

Neuroscience Letters

Volumn 232, Issue 2, 1997, Pages 111-114

  Ikemoto, Keiko ^a,b   Kitahama, Kunio ^a   Jouvet, Anne ^c   Arai, Ryohachi ^b   Nishimura, Akiyoshi ^d   Nishi, Katsuji ^d   Nagatsu, Ikuko ^b  

^a UNIVERSITÉ LYON 1   (France)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Center de Neuropathologie   (France)

^d SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Aromatic L amino acid decarboxylase; Basal ganglia; Dopamine; Immunohistochemistry; L Dopa; Nucleus accumbens; Striatum; Tyrosine hydroxylase

Indexed keywords

LEVODOPA; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL GANGLION; BINDING SITE; CELL SPECIFICITY; CONTROLLED STUDY; CORPUS STRIATUM; DECARBOXYLATION; ENZYME SYNTHESIS; IMMUNOHISTOCHEMISTRY; MONKEY; NONHUMAN; NUCLEUS ACCUMBENS; PARKINSON DISEASE; PRIORITY JOURNAL; TELENCEPHALON;

ADULT; AGED; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; CAUDATE NUCLEUS; CORPUS STRIATUM; HUMANS; IMMUNOHISTOCHEMISTRY; MACACA; MIDDLE AGED; NUCLEUS ACCUMBENS; PUTAMEN; TYROSINE 3-MONOOXYGENASE;

EID: 0030764908     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00587-9     Document Type: Article

References (20)

1. Arai, R., Karasawa, N., Geffard, M. and Nagatsu, I., L-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat, A double-labeling immunofluorescence study, Neurosci. Lett., 195 (1995) 195-198.
2. Dubach, M., Telencephalic dopamine cells in monkeys, humans, and rats. In W.J.A.J. Smeets and A. Reiner (Eds.), Phylogeny and Development of Catecholamine Systems in the CNS of vertebrates, Cambridge University Press, Cambridge, 1994, pp. 273-292.
3. Deutsch, A.Y., Bourdelais, A.J. and Zahm, D.S., The nucleus accumbens core and shell: accumbal compartments and their functional attributes. In P.W. Kalivas and C.D. Barnes (Eds.), Limbic Motor Circuits and Neuropsychiatry, CRC press, Broca Raton, FL, 1993, pp. 45-88.
4. Farley, I.J., Price, K.S., McCullough, E., Deck, J.H.N., Hordynki, W. and Hornykiewicz, O., Norepinephrine in chronic paranoid schizophrenia: above-normal levels in limbic forebrain, Science, 200 (1978) 456-458.
5. Hefti, P., Melamed, E. and Wurtman, R.J., The site of dopamine formation in rat striatum after L-dopa administration, J. Pharmacol. Exp. Ther., 217 (1981) 189-197.
6. Hornykiewicz, O., The mechanism of action of L-dopa in Parkinson's disease, Life Sci., 15 (1974) 1249-1259.
7. Ikemoto, K., Satoh, K., Kitahama, K. and Maeda, T., Demonstration of a new dopamine-containing cell group in the primate telencephalon, Neurosci. Lett., 220 (1996) 69-71.
8. Ikemoto, K., Satoh, K., Maeda, T. and Fibiger, H.C., Neurochemical heterogeneity of the primate nucleus accumbens, Exp. Brain Res., 104 (1995) 177-190.
9. Klawans, H.L., Psychiatric side-effects during the treatment of Parkinson''s disease, J. Neural Transm., 27 (Suppl.) (1988) 117-122.
10. Komori, K., Fujii, T., Karasawa, N., Yamada, K. and Nagatsu, I., Some neurons of the mouse cortex and caudoputamen contain aromatic L-amino acid decarboxylase but not monoamines, Acta Histochem. Cytochem., 24 (1991) 571-577.
11. Mackey, A.V.P., Iversen, L.L., Rossor, M., Spokes, E., Bird, E., Arregui, A., Creese, I. and Snyder, S.H., Increased dopamine and dopamine receptors in schizophrenia, Arch. Gen. Psychiatry, 39 (1982) 991-997.
12. Melamed, E., Hefti, F. and Wurtman, R.J., Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism, Ann. Neurol., 8 (1980) 558-563.
13. Mogenson, G.J., Jones, D.L. and Yim, C.Y., From motivation to action: functional interface between the limbic system and the motor system, Prog. Neurobiol., 14 (1980) 69-97.
14. Mura, A., Jackson, D., Manley, M.S., Young, S.J. and Groves, P.M., Aromatic L-amino acid decarboxylase immunoreactive cells in the striatum: a possible site for the conversion of exogenous L-DOPA to dopamine, Brain Res., 704 (1995) 51-60.
15. Nagatsu, I., Kondo, Y., Inagaki, S., Karasawa, N., Kato, T. and Nagatsu, T., Immunofluorescent studies on tyrosine hydroxylase: application for its axoplasmatic transport, Acta Histochem. Cytochem., 10 (1977) 494-499.
16. Nagatsu, I., Sakai, M., Yoshida, M. and Nagatsu, T., Aromatic L-amino acid decarboxylase-immunoreactive neurons in and around the cerebrospinal fluid-contacting neurons of the central canal do not contain dopamine or serotonin in the mouse and rat spinal cord, Brain Res., 475 (1988) 91-102.
17. Pearson, J., Goldstein, M., Kitahama, K., Sakamoto, N. and Michel, J.P., Catecholaminergic neurons of the human central nervous system. In P. Riederer, N. Kopp and J. Pearson (Eds.), An Introduction to Neurotransmission in Health and Disease, Oxford University Press, New York, 1990, pp. 22-36.
18. Salamone, J.D., Behavioral pharmacology of dopamine systems: a new synthesis. In P. Willner and J. Scheel-Krüger (Eds.), The Mesolimbic Dopamine System: From Motivation to Action, John Wiley, Chichester, 1991, pp. 599-613.
19. Tashiro, Y., Kaneko, T., Sugimoto, T., Nagatsu, I., Kikuchi, H. and Mizuno, N., Striatal neurons with aromatic L-amino acid decarboxylase-like immunoreactivity in the rat, Neurosci. Lett., 100 (1989) 29-34.
20. Tison, F., Mons, N., Geffard, M. and Henry, P., The metabolism of exogenous L-Dopa in the brain: an immunohistochemical study of its conversion to dopamine in non-catecholaminergic cells of the rat striatum, J. Neural Transm., 3 (1991) 27-39.