Structure-activity relationship studies of the amide functionality in (p-O-sulfamoyl)-N-alkanoyl tyramines as estrone sulfatase inhibitors

Steroids

Volumn 62, Issue 7, 1997, Pages 530-535

  Chu, Guo Hua ^a   Milano, Shawn ^a   Kluth, Lisa ^a   Rhodes, Michael ^a   Boni, Riccardo ^a   Johnson, David A ^a   Li, Pui Kai ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

Estrone sulfatase; Hormone dependence; Mammary carcinoma; Sulfatase inhibitors

Indexed keywords

(4 O SULFAMOYL) N TRIDECANOYLTYRAMINE; AMIDE; ENZYME INHIBITOR; ESTRONE; SULFATASE; TYRAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BREAST CANCER; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME BINDING; HORMONE DEPENDENCE; HYDROGEN BOND; STRUCTURE ACTIVITY RELATION;

AMIDES; ENZYME INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATASES; SULFONAMIDES; TYRAMINE;

EID: 0030764441     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(97)00038-X     Document Type: Article

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