Lipofuscin product accumulation, insuficient antioxidant defence in erythrocytes and plasma and enhanced susceptibility to oxidative haemolysis after thermal trauma

Acta Chirurgiae Plasticae

Volumn 39, Issue 2, 1997, Pages 60-64

  Bekyarova, G ^a,b   Yankova, T ^a   Marinov, M ^a  

^a MEDICAL UNIVERSITY OF VARNA   (Bulgaria)

^b NONE   (Bulgaria)

Author keywords

tocopherol; Albumin; Ceruloplasmin; Erythrocytes; GSH; Lipofuscin products; Oxidative haemolysis; Plasma TBARS; SOD; Thermal skin injury

Indexed keywords

ALBUMIN; ALPHA TOCOPHEROL; ANTIOXIDANT; CERULOPLASMIN; GLUTATHIONE; LIPOFUSCIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ALBUMIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BURN; CERULOPLASMIN BLOOD LEVEL; CONTROLLED STUDY; ERYTHROCYTE; HEMOLYSIS; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SKIN INJURY;

ANIMALS; ANTIOXIDANTS; BURNS; ERYTHROCYTES; HEMOLYSIS; LIPOFUSCIN; MALE; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0030763908     PISSN: 03230414     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Yuan, Y., Zhiyang, F.: Change in the rate of hemolysis during the early stage after burns in the rabbit. Burns, 14:365-368, 1988.
2. Zaets, T. L., Lavrov, V. A., Marchuk, A. L., Nosova, I. M.: Changes of several characteristics of the erythrocyte membrane and erythrocyte structure in severe burns in animal experiments. Bull. Experim. Biol. Med., 109:27-30, 1990.
3. Jain, S. K., Mohandas, N., Clark, M. R., Shohet, S. B.: Effect of malondialdehyde on erythrocyte deformability, dehydration and 51 Cr -survival of erythrocytes. Brit. J. Hematol., 53:247-255, 1983.
4. Tappel, A. L.: Lipid peroxidation damage to cell components. Fed. Proc., 32:1870-74, 1973.
5. Jain, S. K.: Evidence for membrane lipid peroxidation during the in vivo aging of human erythrocytes. Biochim. Biophys. Acta, 937:205-210, 1988.
6. Chiu, D., Kuypers, F., Lubin, B.: Lipid peroxidation in human red cells. Semin. Hematol., 26:257-276, 1989.
7. Tamai, H., Miki, M., Mino, M.: Hemolysis and membrane lipid changes induced by xanthine oxidase in vitamin E deficient red cells. J. Free Radic. Biol. Med., 2:49-56, 1986.
8. Sasaki, J., Cottam, G. L., Baxter, C. R.: Lipid peroxidation following thermal injury. J. Burn Care Rehabil., 3/4:251-254, 1983.
9. Meng, X. M.: Mechanism of damage of erythrocytes after burn injury in rat changes in lipid peroxidation, antioxidant function and sulhydril groups. Chin. J. Plast. Surg. Burns, 7:205-207, 1991.
10. Porter, N., Norton, Y., Ramdas, I.: Cyclic peroxidase and the thiobarbituric assay Biochim. Biophys. Acta, 441:596-599, 1976.
11. Dillard, C., Tappel, A. L.: Fluorescence of lipid peroxidation damage products. In: L. Parker (Ed), Methods in Enzymology, 105, Oxygen Radicals in Biological Systems, Acad. Press, New York, pp. 337-341, 1984.
12. Taylor, S. L., Lamden, M. P., Tappel, A. L.: Sensitive fluorimetric method for tissue tocopherol analysis. Lipids, 11:530-538, 1976.
13. Hissin, P. J., Hilf, R. A.: A fluorimetric method for determination of oxidized and reduced glutathione in tissue. Anal Biochem., 74:214-226, 1976.
14. Misra, H. P., Fridovich, T. P : The role of Superoxide anion in the antioxidant of epinephrine and simple assay for Superoxide dismutase. J. Biol. Chem., 247:3170-3175, 1972.
15. Ravin, H. A.: Standard methods in the clinical chemistry. J. Lab. Clin. Med., 58:161-164, 1961.
16. Farell, P. M., Bieri, G., Fratantoni, J. E.: The occurrence of effects of human vitamin E deficiency - a study in patients with cyctic fibrosis. J. Clin. Invest., 60:133-137, 1977.
17. Bekyarova, G., Yankova, T., Yankov, D., Kozarev, I.: Erythrocyte rheology and lipid peroxidation in burns. Biomed. Biophys. Acta, 50:71-76, 1991.
18. Saitoh, D., Okada, Y., Takahara, T., et al.: The effect of an SOD derivated (SM-SOD) administration in the burned rat model. Tohoku J. Exp. Med., 174:31-40, 1994.
19. Hatherill, J. R., Till, G. O., Bruner, L. H., et al.: Thermal injury, intravascular hemolysis and toxic oxygen products. J. Clin. Invest., 78:629-636, 1986.
20. Bekyarova, G., Kozarev, I., Yankova, T.: Dependence between the free radical peroxidation, the activity of Superoxide dismutase, glucose-6-phosphate dehydrogenase and erythrocyte hemolysis after thermal trauma and tocopherol treatment. Acta Physiol. Pharmacol. Bulg., 15:268-273, 1989.
21. Saez, J. C., Ward, P. H., Gunther, B., Vivaldi, E.: Superoxide radicals involvment in the pathogenesis of burn shock. Circ. Shock, 12:229-239, 1984.
22. Nguen, T. T., Cox, C. S., Traber, B. L., et al.: The radical activity and loss of plasma antioxidant vitamin E and sulfhydrill groups in patients with burns: The 1993 Moyer Award. J. Burn Care Rehabil., 14:602-, 1993.
23. Ward, P. A., Till, G. O.: Pathophysiologic events related to thermal injury of skin. J. Trauma, 30:S76-79, 1990.
24. Oldham, K. T., Guice, K. S., Till, G. O., et al.: Activation of complement by hydroxyl radical in thermal injury. Surgery, 104:272-279, 1988.
25. Burton, L. K., Velasco, S. E., Patt, A., Terada, L. S., Repine, J. E.: Xanthine oxidase contributes to lung leak in rats subjected to skin burn. Inflamation, 19:31-38, 1995.
26. Tomas, C. E., Morehouse, L. A., Aust, S. D.: Ferritin and Superoxide dependent lipid peroxidation. J. Biol. Chem., 260:3275-3280, 1984.
27. Burton, G. W., Joyce, A., Ingold, K. V.: Is vitamin E the only lipid soluble, chain-breaking antioxidant in human plasma and erythrocyte membranes. Arch. Biochem. Biophys., 221:281-290, 1983.
28. Chow, C. K.: Vitamin E and antioxidative stress. Free Radic. Biol. Med., 11:215-232, 1991.
29. Kagan, V. E., Serbinova, E. A., Forte, T., Scita, G., Parker, L.: Recicling of vitamin E in human low density lipoprotein. J. Lipid Res., 33:385-397, 1992.
30. Denek, M. S., Farburg, L. B.: Regulation of cellular glutathione. Am. J. Physiol., 257:L163-173, 1989.
31. Baar, S.: Anaemia of burns. Burns, 6:1-8, 1979.
32. Halliwell, B. H., Guteridge, J. M. C.: The antioxidants of human extracellular fluids. Arch. Biochem. Biophys., 280:1-8, 1990.
33. Halliwell, B. H., Guteridge, J. M. C.: Oxygen radicals, transition methals and disease. Biochem. J., 219:1-14, 1984.
34. Vasil, M., Halliwel, B., Hutchison, D. C. S., Baun, H.: The antioxidant action of extracellular fluids. Biochem. J., 243:219-223, 1987.
35. Shao, H.: Effect of lipoperoxide on catabolism of protein in burns in rats. Chin. J. Surg. & Burns, 29:581-583, 1991.