Biodegradable polymeric device for sustained intravitreal release of ganciclovir in rabbits

Current Eye Research

Volumn 16, Issue 7, 1997, Pages 633-639

  Hashizoe, Mototane ^a   Ogura, Yuichiro ^a   Takanashi, Taiji ^a   Kunou, Noriyuki ^a   Honda, Yoshihito ^a   Ikada, Yoshito ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

AIDS; Cytomegalovirus retinitis; Ganciclovir; Polymeric device; Sustained drug release

Indexed keywords

GANCICLOVIR; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; CILIARY DISK; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG IMPLANTATION; DRUG RELEASE; ELECTRON MICROSCOPY; ELECTRORETINOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTRAVITREAL DRUG ADMINISTRATION; MICROSCOPY; MOLECULAR WEIGHT; NONHUMAN; OPHTHALMOSCOPY; PRIORITY JOURNAL; RABBIT; RETINITIS; SPECTROPHOTOMETRY; SUSTAINED DRUG RELEASE; VITREOUS BODY;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; GANCICLOVIR; LACTIC ACID; POLYGLYCOLIC ACID; POLYMERS; PROSTHESES AND IMPLANTS; RABBITS; VITREOUS BODY;

EID: 0030763787     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.16.7.633.5063     Document Type: Article

References (35)

1. Holland, G. N., Gottlieb, M. S., Yee, R. D., Schanker, H. M. and Pettit, T. H. (1982) Ocular disorders associated with a new severe acquired cellular immunodeficiency syndrome. Am. J. Ophthalmol. 93, 393-402.
2. Newman, N. M., Mandel, M. R., Gullett, J. and Fujikawa, L. (1983) Clinical and histologic findings in opportunistic ocular infections: part of a new syndrome of acquired immunodeficiency. Arch. Ophthalmol. 101, 396-401.
3. Holland, G. N., Pepose, J. S., Pettit, T. H., Gottlieb, M. S., Yee, R. D. and Foos, R. Y. (1983) Acquired immune deficiency syndrome: ocular manifestations. Ophthalmology, 90, 859-873.
4. Freeman, W. R., Lerner, C. W., Mines, J. A., Lash, R. S., Nadel, A. J., Starr, M. B. and Tapper, M. L. (1984) A prospective study of the ophthalmologic findings in the acquired immune deficiency syndrome. Am. J. Ophthalmol. 97, 133-142.
5. Khadem, M., Kalish, S. B., Goldsmith, J., Fetkenhour, C., O'Grady, R. B., Phair, J. P. and Chrobak, M. (1984) Ophthalmologic findings in acquired immune deficiency syndrome (AIDS). Arch. Ophthalmol. 102, 201-206.
6. Palestine, A. G., Rodrigues, M. M., Macher, A. M., Chan, C. C., Lane, H. C., Fauci, A. S., Masur, H., Longo, D., Reichert, C. M. and Steis, R. (1984) Ophthalmic involvement in acquired immunodeficiency syndrome. Ophthalmology, 91, 1092-1099.
7. Pepose, J. S., Holland, G. N., Nestor, M. S., Cochran, A. J. and Foos, R. Y. (1985) Acquired immune deficiency syndrome: pathogenic mechanisms of ocular disease. Ophthalmology, 92, 472-484.
8. Jabs, D. A., Enger, C. and Bartlett, J. G. (1989) Cytomegalovirus retinitis and acquired immunodeficiency syndrome. Arch. Ophthalmol. 107, 75-80.
9. Lehoang, P., Girard, B., Robinet, M., Marcel, P., Zazoun, L., Matheron, S., Rozenbaum, W., Katlama, C., Morer, I. and Lernestedt, J. O. (1989) Foscarnet in the treatment of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology, 96, 865-873.
10. Holland, G. N., Sison, R. F., Jatulis, D. E., Haslop, M. G., Sakamoto, M. J. and Wheeler, N. C. (1990) Survival of patients with the acquired immune deficiency syndrome after development of cytomegalovirus retinopathy: UCLA CMV retinopathy study group. Ophthalmology, 97, 204-211.
11. Gross, J. G., Bozzette, S. A., Mathews, W. C., Spector, S. A., Abramson, I. S., McCutchan, J. A., Mendez, T., Munguia, D. and Freeman, W. R. (1990) Longitudinal study of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology, 97, 681-686.
12. Henderly, D. E., Freeman, W. R., Causey, D. M. and Rao, N. A. (1987) Cytomegalovirus retinitis and response to therapy with ganciclovir. Ophthalmology, 94, 425-434.
13. Holland, G. N., Sidikaro, Y., Kreiger, A. E., Hardy, D., Sakamoto, M. J., Frenkel, L. M., Winston, D. J., Gottlieb, M. S., Bryson, Y. J. and Champlin, R. E. (1987) Treatment of cytomegalovirus retinopathy with ganciclovir. Ophthalmology, 94, 815-823.
14. Jabs, D. A., Newman, C., De, B. S. and Polk, B. F. (1987) Treatment of cytomegalovirus retinitis with ganciclovir. Ophthalmology, 94, 824-830.
15. Orellana, J., Teich, S. A., Friedman, A. H., Lerebours, F., Winterkorn, J. and Mildvan, D. (1987) Combined short-and long-term therapy for the treatment of cytomegalovirus retinitis using ganciclovir (BW B759U). Ophthalmology, 94, 831-838.
16. Henry, K., Cantrill, H., Fletcher, C., Chinnock, B. J. and Balfour, H. J. (1987) Use of intravitreal ganciclovir (dihydroxy propoxymethyl guanine) for cytomegalovirus retinitis in a patient with AIDS. Am. J. Ophthalmol. 103, 17-23.
17. Ussery, F. III, Gibson, S. R., Conklin, R. H., Piot, D. F., Stool, E. W. and Conklin, A. J. (1988) Intravitreal ganciclovir in the treatment of AIDS-associated cytomegalovirus retinitis. Ophthalmology, 95, 640-648.
18. Cantrill, H. L., Henry, K., Melroe, N. H., Knobloch, W. H., Ramsay, R. C. and Balfour, H., Jr. (1989) Treatment of cytomegalovirus retinitis with intravitreal ganciclovir: long-term results. Ophthalmology, 96, 367-374.
19. Heinemann, M. H. (1989) Long-term intravitreal ganciclovir therapy for cytomegalovirus retinopathy. Arch. Ophthalmol. 107, 1767-1772.
20. Cochereau, M. I., Lehoang, P., Lautier, F. M., Zazoun, L., Marcel, P., Robinet, M., Matheron, S., Katlama, C., Gharakhanian, S. and Rozenbaum, W. (1991) Efficacy and tolerance of intravitreal ganciclovir in cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology, 98, 1348-1353.
21. Peyman, G. A., Khoobehi, B., Tawakol, M., Schulman, J. A., Mortada, H. A., Alkan, H. and Fiscella, R. (1987) Intravitreal injection of liposome-encapsulated ganciclovir in a rabbit model. Retina, 7, 227-229.
22. Shakiba, S., Assil, K. K., Listhaus, A. D., Munguia, D., Flores, A. M., Vuong, C., Wiley, C. A., Tolman, R. L., Karkas, J. D. and Bergeron, L. G. (1993) Evaluation of retinal toxicity and liposome encapsulation of the anti-CMV drug 2′-nor-cyclic GMP. Invest. Ophthalmol. Vis. Sci. 34, 2903-2910.
23. Sanborn, G. E., Anand, R., Torti, R. E., Nightingale, S. D., Cal, S. X., Yates, B., Ashton, P. and Smith, T. (1992) Sustained-release ganciclovir therapy for treatment of cytomegalovirus retinitis. Use of an intravitreal device. Arch. Ophthalmol. 110, 188-195.
24. Smith, T. J., Pearson, P. A., Blandford, D. L., Brown, J. D., Goins, K. A., Hollins, J. L., Schmeisser, E. T., Glavinos, P., Baldwin, L. B. and Ashton, P. (1992) Intravitreal sustained-release ganciclovir. Arch. Ophthalmol. 110, 255-258.
25. Anand, R., Nightingale, S. D., Fish, R. H., Smith, T. J. and Ashton, P. (1993) Control of cytomegalovirus retinitis using sustained release of intraocular ganciclovir. Arch. Ophthalmol. 111, 223-227.
26. Kimura, H., Ogura, Y., Hashizoe, M., Nishiwaki, H., Honda, Y. and Ikada, Y. (1994) A new vitreal drug delivery system with an implantable biodegradable polymer device. Invest. Ophthalmol. Vis. Sci. 35, 2815-2819.
27. Hashizoe, M., Ogura, Y., Kimura, H., Honda, Y., Kyo, M., Hyon, S. H. and Ikada, Y. (1994) Scleral plug of biodegradable polymers for controlled drug release in the vitreous. Arch. Ophthalmol. 112, 1380-1384.
28. Hashizoe, M., Ogura, Y., Takanashi, T., Honda, Y. and Ikada, Y. (1995) Implantable biodegradable polymeric device containing adriamycin in the treatment of experimental proliferative vitreoretinopathy. Curr. Eye Res. 14, 473-477.
29. Kunou, N., Ogura, Y., Hashizoe, M., Honda, Y., Hyon, S. H. and Ikada, Y. (1995) Controlled delivery of ganciclovir with biodegradable scleral implant in rabbits. J. Controlled Release, 37, 143-150.
30. Mar, E. C., Cheng, Y. C. and Huang, E. S. (1983) Effect of 9-(1,3-dihydroxy-2-propoxymethyl) guanine on human cytomegalovirus replication in vitro. Antimicrob. Agents Chemother. 24, 518-521.
31. Martin, J. C., Dvorak, C. A., Smee, D. F., Matthews, T. R. and Verheyden, J. P. (1983) 9-[(1,3-Dihydroxy-2-propoxy) methyl]guanine: a new potent and selective antiherpes agent. J. Med. Chem. 26, 759-761.
32. Tocci, M. J., Livelli, T. J., Perry, H. C., Crumpacker, C. S. and Field, A. K. (1984) Effects of the nucleoside analog 2′-nor-2′-deoxyguanosine on human cytomegalovirus replication. Antimicrob. Agents Chemother. 25, 247-252.
33. Plotkin, S. A., Drew, W. L., Felsenstein, D. and Hirsch, M. S. (1985) Sensitivity of clinical isolates of human cytomegalovirus to 9-(1,3-dihydroxy-2-propoxymethyl) guanine. J. Infect. Dis. 152, 833-834.
34. Nakamura, T., Mizuno, H., Tamura, K., et al. (1986) Bioabsorption of polylactides. Jpn. J. Artif. Organs 15, 264-267.
35. Rubsamen, P. E., Davis, P. A., Hernandez, E., O'Grady, G. E. and Cousins, S. W. (1994) Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal implant for the sustained release of fluorouracil. Arch. Ophthalmol. 112, 407-413.