Differential expression of apoptosis, Bcl-x and c-Myc in normal and malignant lymphoid tissues

European Journal of Haematology

Volumn 59, Issue 1, 1997, Pages 20-30

  Hermann, M ^a,b   Scholman, H J ^a   Marafioti, T ^a   Stein, H ^a   Schriever, F ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Apoptosis; Bcl x; c Myc; Lymphoid tissues

Indexed keywords

ONCOPROTEIN; PROTEIN BCL X; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; ONCOGENE C MYC; PRIORITY JOURNAL;

EID: 0030763064     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1997.tb00955.x     Document Type: Article

References (48)

1. COHEN JJ, DUKE RC, FADOK VA, SELLINS KS. Apoptosis and programmed cell death in immunity. Annu Rev Immunol 1992: 10: 267-293.
2. BOISE LH, GONZALEZ-GARCIA M, POSTEMA CE, et al. bcl-x. a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993: 74: 597-608.
3. CHAD DT, LINETTE GP, BOISE LH, WHITE LS, THOMPSON CB, KORSMEYER SJ. Bel-XL and Bcl-2 repress a common pathway of cell death. J Exp Med 1995: 182: 821-828.
4. KLEFSTROM J, VASTRIK I, SAKSELA E, VALLE J, EILERS M, ALITALO K. c-Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha. EMBO J 1994: 13: 5442-5450.
5. EVAN GI, WYLLIE AH, GILBERT CS, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992: 69: 119-128.
6. MILNER AE, GRAND RJ, WATERS CM, GREGORY CD. Apoptosis in Burkitt's lymphoma cells is driven by c-myc. Oncogene 1993: 8: 3385-3391.
7. DALLA FAVERA R, BREGNI M, ERIKSON J, PATTERSON D, GALLO RC, CROCK CM. Human c-myc one gene is located on the region of chromosome 8 that is translocated in Burkitt's lymphoma cells. Proc Natl Acad Sci USA 1982: 79: 7824-7827.
8. LADANYI M, OFFIT K, JHANWAR SC, FILIPA DA, CHAGANTI RSK. Myc rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas. Blood 1991: 77: 1057-1063.
9. STANSFELD AG, DIEBOLD J, NOEL H, et al. Updated Kiel classification for lymphomas (letter) (published erratum appears in Lancet 1988 Feb 13; 1 (8581): 372). Lancet 1988: 1: 292-293.
10. HARRIS NL, JAFFE ES, STEIN H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the international lymphoma study group. Blood 1994: 84: 1361-1392.
11. EVAN GI, LEWIS GK, RAMSAY G, BISHOP JM. Isolation of monoclonal antibodies specific for human c-myc protooncogene product. Mol Cell Biol 1985: 5: 3610-3616.
12. GAVRIELI Y, SHERMAN Y, BEN-SASSON SA. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 1992: 119: 493-501.
13. SURH CD, SPRENT J. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 1994: 372: 100-103.
14. MURO CACHO CA, PANTALEO G, FAUCI AS. Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 1995: 154: 5555-5566.
15. GORCZYCA W, GONG J, DARZYNKIEWICZ Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 1993: 53: 1945-1951.
16. LE PT, MAECKER HT, COOK JE. In situ detection and characterization of apoptotic thymocytes in human thymus. Expression of bcl-2 in vivo does not prevent apoptosis. J Immunol 1995: 154: 4371-4378.
17. SCHRIEVER F, FREEDMAN AS, FREEMAN G, et al. Isolated human follicular dendritic cells display a unique antigenic phenotype. J Exp Med 1989: 169: 2043-2058.
18. BEHR S, SCHRIEVER F. Engaging CD19 or target of an antiproliferative antibody 1 on human B lymphocytes induces binding of B-cells to the interfollicular stroma of human tonsils via integrin alpha 4/beta 1 and fibronectin. J Exp Med 1995: 182: 1191-1199.
19. LEONCINI L, DEL VECCHIO MT, SPINA D, et al. Presence of the bcl-2 protein and apoptosis in non-Hodgkin lymphomas with diffuse growth pattern. Int J Cancer 1995: 61: 826-831.
20. LEONCINI L, DEL VECCHIO MT, MEGHA T, et al. Correlations between apoptotic and proliferative indices in malignant non-Hodgkin's lymphomas. Am J Pathol 1993: 142: 755-763.
21. SPINA D, LEONCINI L. DEL VECCHIO MT, et al. Low versus high cell turnover in diffusely growing non-Hodgkin's lymphomas. J Pathol 1995: 177: 335-341.
22. KOBAYASHI M, WATANABE H, AJIOKA Y, YOSHIDA M, HITOMI J, ASAKURA H. Correlation of p53 protein expression with apoptotic incidence in colourectal neoplasia. Virchows Arch 1995: 427: 27-32.
23. BEDI A, PASRICHA PJ, AKHTAR AJ, et al. Inhibition of apoptosis during development of colourectal cancer. Cancer Res 1995: 55: 1811-1816.
24. KERR JFR, WYLLIE AH, CURRIE AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972: 26: 239-257.
25. WYLLIE AH. Apoptosis. Br J Cancer 1993: 67: 205-208.
26. UEDA N, SHAH SV. Apoptosis. J Lab Clin Med 1994: 124: 169-177.
27. KRAJEWSKI S, KRAJEWSKA M, SHABAIK A, et al. Immunohistochemical analysis of in vivo patterns of Bcl-X expression. Cancer Res 1994: 54: 5501-5507.
28. WILLIAMS AR, PIRIS J, WYLLIE AH. Immunohistochemical demonstration of altered intracellular localization of the c-Myc oncogene product in human colourectal neoplasms. J Pathol 1990: 160: 287-293.
29. PEZZELLA F, GATTER K. What is the value of bcl-2 protein detection for histopathologists? Histopathology 1995: 26: 89-93.
30. TSUJIMOTO Y, COSSMAN J, JAFFE E, CROCE C. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985: 228: 1440-1443.
31. ZUTTER M, HOCKENBERY D, SILVERMAN GA, KORSMEYER SJ. Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms. Blood 1991: 78: 1062-1068.
32. YANG E, KORSMEYER SJ. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996: 88: 386-401.
33. PIRIS MA, PEZZELLA F, MARTINEZ MONTERO JC, et al. p53 and bcl-2 expression in high-grade B-cell lymphomas: correlation with survival time (published erratum appears in Br J Cancer 1994 May; 69(5): 978). Br J Cancer 1994: 69: 337-341.
34. STEIN H, GERDES J, MASON DY. The normal and malignant germinal centre. Clin Haematol 1982: 11: 531-559.
35. PETRASCH S, KOSCO M, SCHMITZ J, WACKER HH, BRITTINGER G. Follicular dendritic cells in non-Hodgkin-lymphoma express adhesion molecules complementary to ligands on neoplastic B-cells. Br J Haematol 1992: 82: 695-700.
36. FREEDMAN AS, MUNRO JM, MORIMOTO C, et al. Follicular non-Hodgkin's lymphoma cell adhesion to normal germinal centers and neoplastic follicles involves very late antigen-4 and vascular cell adhesion molecule-1. Blood 1992: 79: 206-212.
37. TUSCANO JM, DRUEY KM, RIVA A, PENA J, THOMPSON CB, KEHRL JH. Bcl-x rather than Bcl-2 mediates CD40-dependent centrocyte survival in the germinal center. Blood 1996: 88: 1359-1364.
38. KRAJEWSKA M, Moss SF, KRAJEWSKI S, SONG K, HOLT PR, REED JC. Elevated expression of Bcl-X and reduced Bak in primary colourectal adenocarcinomas. Cancer Res 1996: 56: 2422-2427.
39. XERRI L, PARC P, BROUSSET R et al. Predominant expression of the long isoform of Bcl-x ( Bcl-xL) in human lymphomas. Br J Haematol 1996: 92: 900-906.
40. SEDLAK TW, OLTVAI ZN, YANG E, et al. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 1995: 92: 7834-7838.
41. YANG E, ZHA J, JOCKEL J, BOISE LH, THOMPSON CB, KORSMKYER SJ. Bad, a heterodimeric partner for Bel-XL and Bcl-2, displaces Bax and promotes cell death. Cell 1995: 80: 285-291.
42. SCHLAIFER D, KRAJEWSKI S, GALOIN S, et al. Immunodetection of apoptosis-regulating proteins in lymphomas from patients with and without human immunodeficiency virus infection. Am J Pathol 1996: 149: 177-185.
43. RIGAL HUGUET F, GOPAS J, PRINSLOO I, et al. Frequent expression of the cell death-inducing gene Bax in Reed-Sternberg cells of Hodgkin's disease. Blood 1996: 87: 2470-2475.
44. HARRINGTON EA, BENNETT MR, FANIDI A, EVAN GI. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 1994: 13: 3286-3295.
45. FAMDI A, HARRINGTON EA, EVAN GI. Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 1992: 359: 554-556.
46. BISSONNETTE RP, ECHEVERRI F, MAHBOUBI A, GREEN DR. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992: 359: 552-554.
47. SHAW G, KAMEN R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 1986: 46: 659-667.
48. CIECHANOVER A, DIGIUSEPPE JA, BERCOVICH B, et al. Degradation of nuclear oncoproteins by the ubiquitin system in vitro. Proc Natl Acad Sci USA 1991: 88: 139-143.