Bicyclo[10.2.1]pentadecenone derivatives by free radical macrocyclisation

Tetrahedron

Volumn 53, Issue 43, 1997, Pages 14807-14820

  Robertson, Jeremy ^a   Burrows, Jeremy N ^a,b   Stupple, Paul A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BICYCLO[10.2.1]PENTADECENONE DERIVATIVE; CYCLOPENTENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; STEREOISOMERISM;

EID: 0030762824     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00990-3     Document Type: Article

References (30)

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15. For a review of allylic displacement chemistry see Magid, R. M. Tetrahedron, 1980, 36, 1901-1930; for a discussion of the stereochemistry and mechanism of allylic displacements with cuprate reagents see Corey, E. J.; Boaz, N. W. Tetrahedron Lett., 1984, 25, 3063-3066; examples of syn-stereoselective addition to lactones related in structure to 5 are known, e.g. Trost, B. M.; Verhoeven, T. R. J. Am. Chem. Soc., 1980, 102, 4730-4743; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1996, 61, 1192-1193; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1997, 62, 4665-4671.
16. For a review of allylic displacement chemistry see Magid, R. M. Tetrahedron, 1980, 36, 1901-1930; for a discussion of the stereochemistry and mechanism of allylic displacements with cuprate reagents see Corey, E. J.; Boaz, N. W. Tetrahedron Lett., 1984, 25, 3063-3066; examples of syn-stereoselective addition to lactones related in structure to 5 are known, e.g. Trost, B. M.; Verhoeven, T. R. J. Am. Chem. Soc., 1980, 102, 4730-4743; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1996, 61, 1192-1193; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1997, 62, 4665-4671.
17. For a review of allylic displacement chemistry see Magid, R. M. Tetrahedron, 1980, 36, 1901-1930; for a discussion of the stereochemistry and mechanism of allylic displacements with cuprate reagents see Corey, E. J.; Boaz, N. W. Tetrahedron Lett., 1984, 25, 3063-3066; examples of syn-stereoselective addition to lactones related in structure to 5 are known, e.g. Trost, B. M.; Verhoeven, T. R. J. Am. Chem. Soc., 1980, 102, 4730-4743; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1996, 61, 1192-1193; Aggarwal, V. K.; Monteiro, N.; Tarver, G. J.; Lindell, S. D. J. Org. Chem., 1997, 62, 4665-4671.
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