Differential display reveals transcriptional up-regulation of the motor molecules for both anterograde and retrograde axonal transport during nerve regeneration

European Journal of Neuroscience

Volumn 9, Issue 7, 1997, Pages 1542-1547

  Su, Q N ^a   Namikawa, K ^a   Toki, H ^b   Kiyama, H ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Differential display; Dynein; Kinesin; Mouse; Nerve injury; RAP

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; GROWTH FACTOR; KINESIN; MESSENGER RNA; OLIGONUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EFFERENT NERVE; HYPOGLOSSAL NERVE; IN SITU HYBRIDIZATION; MALE; MEMBRANE VESICLE; MOTONEURON; MOTOR NERVE; MOUSE; NERVE FIBER TRANSECTION; NERVE FIBER TRANSPORT; NERVE INJURY; NERVE REGENERATION; NONHUMAN; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROGRADE NERVE FIBER TRANSPORT; RNA FINGERPRINTING; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; AXONS; BASE SEQUENCE; BIOLOGICAL TRANSPORT, ACTIVE; BRAIN; DENERVATION; DYNEIN ATPASE; HYPOGLOSSAL NERVE; IN SITU HYBRIDIZATION; KINESIN; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NERVE REGENERATION; POLYMERASE CHAIN REACTION; RATS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0030762760     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01510.x     Document Type: Article

References (22)

1. Aizawa, H., Sekine, Y., Takemura, R., Zhang, Z., Nangaku, M. and Hirokawa, N. (1992) Kinesin family in murine central nervous system. J. Cell Biol, 119, 1287-1296.
2. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
3. Curtis, R., Adryan, K. M., Zhu, Y., Harkness, P. J., Lindsay, R. M. and DiStefano, P. S. (1993) Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury. Nature, 365, 253-255.
4. Curtis, R., Scherer, S. S., Somogyi, R., Adryan, K. M., Ip, N. Y, Zhu, Y, Lindsay, R. M. and DiStefano, P. S. (1994) Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron, 12, 191-204.
5. Cyr, J. L., Pfister, K. K., Bloom, G. S., Slaughter, C. A. and Brady, S. T. (1991) Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc. Natl Acad. Sci. USA, 88, 10114-10118.
6. Ferreira, A., Niclas, J., Vale, R. D., Banker, G. and Kosik, K. S. (1992) Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. J. Cell Biol., 117, 595-606.
7. Gindhart, J. G. and Goldstein, L. S. B. (1996) Tetratrico peptide repeats are present in the kinesin light chain. Trends Biochem. Sci., 21, 52-53.
8. Gudkov, A. V., Kazarov, A. R., Thimmapaya, R., Axenovich, S. A., Mazo, I. A. and Roninson, I. B. (1994) Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc. Natl Acad. Sci. USA, 91, 3744-3748.
9. Hirokawa, N. (1993) Axonal transport and the cytoskeleton. Curr. Opin. Neurobiol, 3, 724-731.
10. Hökfelt, T., Zhang, X. and Wiesenfeld, H. Z. (1994) Messenger plasticity in primary sensory neurons following axotomy and its functional implications [see comments]. Trends Neurosci., 17, 22-30.
11. Kalo, K. (1990) A collection of cDNA clones with specific expression patterns in mouse brain. Ear. J. Neurosci., 2, 704-711.
12. Kiryu, S., Morita, N., Ohno, K., Maeno, H. and Kiyama, H. (1995a) Regulation of mRNA expression involved in Ras and PKA signal pathways during rat hypoglossal nerve regeneration. Mol. Brain Res., 29, 147-156.
13. Kiryu, S., Yao, G. L., Morita, N., Kato, H. and Kiyama, H. (1995b) Nerve injury enhances rat neuronal glutamate transporter expression: identification by differential display. J. Neurosci., 15, 7872-7878.
14. Kitahara, T., Kiryu, S., Takeda, N., Kubo, T. and Kiyama, H. (1995) Up-regulation of ferritin heavy chain mRNA expression in the rat skeletal muscle after denervation: detected by means of differential display. Neurosci. Res., 23, 353-360.
15. Liang, P. and Pardee, A. B. (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science, 257, 967-971.
16. Morita, N., Namikawa, K. and Kiyama, H. (1995) Up-regulation of PKA RI alpha subunit mRNA in rat skeletal muscle after nerve injury. NeuroReport, 6, 1050-1052.
17. Navone, F., Niclas, J., Horn, B. N., Sparks, L., Bernstein, H. D., McCaffrey, G. and Vale, R. D. (1992) Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. J. Cell Biol., 117, 1263-1275.
18. Niclas, J., Navone, F., Horn, B. N. and Vale, R. D. (1994) Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. Neuron, 12, 1059-1072.
19. Saika, T., Kiyama, H., Tohyama, M. and Matsunaga, T. (1993) GAP-43 mRNA expression in facial motoneurons during regeneration: in situ hybridization histochemistry study using an alkaline phosphatase-labelled probe. Acta Oto-Laryngol. Suppl, 501, 80-84.
20. Takemura, R., Nakata, T., Yakamaki, H., Zhang, Z. and Hirokawa, N. (1996) mRNA expression of KIFA, KIFB, KIF2, KIF3A, KIF3B, KIF4, KIF5, and cytoplasmic dynein during axonal regeneration. J. Neurosci., 16, 31-35.
21. Welsh, J., Chada, K., Dalai, S. S., Cheng, R., Ralph, D. and McClelland, M. (1992) Arbitrarily primed PCR fingerprinting of RNA. Nucleic Acids Res., 20, 4965-4970.
22. Zhang, Z., Tanaka, Y., Nonaka, S., Aizawa, H., Kawasaki, H., Nakata, T. and Hirokawa, N. (1993) The primary structure of rat brain (cytoplasmic) dynein heavy chain, a cytoplasmic motor enzyme. Proc. Natl Acad. Sci. USA, 90, 7928-7932.