Regional densities of benzodiazepine sites in the CNS of alcohol-naive P and NP rats

Pharmacology Biochemistry and Behavior

Volumn 57, Issue 4, 1997, Pages 875-882

  Thielen, R J ^a,b   McBride, W J ^b   Chernet, E ^b   Lumeng, L ^b   Li, T K ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol preferring rats; Autoradiography; Benzodiazepine recognition sites; Flunitrazepam binding; GABA(A) receptors

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; BENZODIAZEPINE RECEPTOR; FLUNITRAZEPAM; RECEPTOR SUBTYPE;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DENTATE GYRUS; ENTORHINAL CORTEX; FRONTAL CORTEX; HIPPOCAMPUS; LATERAL HYPOTHALAMUS; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PARIETAL LOBE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SUBSTANTIA NIGRA; SUPERIOR COLLICULUS; THALAMUS;

ALCOHOL DRINKING; ANIMALS; AUTORADIOGRAPHY; BENZODIAZEPINES; BRAIN; FLUNITRAZEPAM; GAMMA-AMINOBUTYRIC ACID; MALE; RATS; RECEPTORS, GABA-A;

ANIMALIA;

EID: 0030762749     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00464-9     Document Type: Article

References (43)

1. - current in mouse hippocampal and cortical neurons. Eur. J. Pharmacol. 187:127-130; 1990.
2. Allan, A. M.; Harris, R. A.: Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice. Life Sci. 39:2005-2015; 1986.
3. 3H]zolpidem binding in the rat brain: An imidazopyridine with agonist properties at central benzodiazepine receptors. Eur. J. Pharmacol. 130:257-263; 1986.
4. Bowers, B. J.; Wehner, J. M.: Interaction of ethanol and stress with the GABA/BZ receptor in LS and SS mice. Brain Res. Bull. 23:53-59; 1989.
5. Bowers, B. J.; Wehner, J. M.: Adrenalectomy and stress modulate GABAA receptor function in LS and SS mice. Brain Res. 576:80-88; 1992.
6. 1 benzodiazepine receptor subclass. J. Neurochem. 37:333-341; 1981.
7. Criswell, H. E.; Simson, P. E.; Duncan, G. E.; McCown, T. J.; Herbert, J. S.; Morrow, A. L.; Breese, G. R.: Molecular basis for regionally specific action of ethanol on γ-aminobutyric acidA receptors: Generalization to other ligand-gated ion channels. J. Pharmacol. Exp. Ther. 267:522-537; 1993.
8. Criswell, H. E.; Simson, P. E.; Knapp, D. J.; Devaud, L. L.; McCown, T. J.; Duncan, G. E.; Morrow, A. L.; Breese, G. R.: Effect of zolpidem on γ-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions. J. Pharmacol. Exp. Ther. 273:526-536; 1995.
9. Handley, S. L.: 5-Hydroxytryptamine pathways in anxiety and its treatment. Pharmacol. Ther. 66:103-148; 1995.
10. Harris, R. A.; Allan, A. M.; Daniell, L. C.; Nixon, C.: Antagonism of ethanol and pentobarbital actions by benzodiazepine inverse agonists: Neurochemical studies. J. Pharmacol. Exp. Ther. 247: 1012-1017; 1988.
11. Hwang, B. H.; Lumeng, L.; Wu, J.-Y.; Li, T.-K.: Increased number of GABAergic terminals in the nucleus accumbens is associated with alcohol preference in rats. Alcohol. Clin. Exp. Res. 14: 503-507; 1990.
12. Kang, I.; Thompson, M. L.; Heller, J.; Miller, L. G.: Persistent elevation in GABAA receptor subunit mRNAs following social stress. Brain Res. Bull. 26:809-812; 1991.
13. Li, T.-K.; Lumeng, L.; McBride, W. J.; Murphy, J. M.: Rodent lines selected for factors affecting alcohol consumption. Alcohol Suppl. 1:91-96; 1987.
14. Li, T.-K.; Lumeng, L.; McBride, W. J.; Waller, M. B.: Indiana selection studies on alcohol-related behaviors. In: McClearn, G. E.; Deitrich, R. A.; Erwin, V. G., eds. Development of animal models as pharmacogenetic tools. NIAAA Research Monograph No. 6. Rockville, MD: NIAAA; 1981:171-192.
15. Lumeng, L.; Hawkins, T. D.; Li, T.-K.: New strains of rats with alcohol preference and nonpreference. In: Thurman, R. F.; Williamson, J. R.; Drott, H. R.; Chance, B., eds. Alcohol and aldehyde metabolizing systems, vol. 3. New York: Academic Press; 1977:537-544.
16. Lumeng, L.; Waller, M. B.; McBride, W. J.; Li, T.-K.: Different sensitivities to ethanol in alcohol-preferring and -nonpreferring rats. Pharmacol. Biochem. Behav. 16:125-130; 1982.
17. Malminen, O.; Korpi, E. R.: GABA/benzodiazepine receptor/chloride ionophore complex in brains of rat lines selectively bred for differences in the ethanol-induced motor impairment. Alcohol 5:239-249; 1988.
18. Marley, R. J.; Miner, L. L.; Wehner, J. M.; Collins, A. C.: Differential effects of central nervous system depressants in long-sleep and short-sleep mice. J. Pharmacol. Exp. Ther. 238:1028-1033; 1986.
19. Marley, R. J.; Freund, R. K.; Wehner, J. M.: Differential response to flurazepam in long-sleep and short-sleep mice. Pharmacol. Biochem. Behav. 31:453-458; 1988.
20. McBride, W. J.; Chernet, E.; Rabold, J. A.; Lumeng, L.; Li, T.-K.: Serotonin-2 receptors in the CNS of alcohol-preferring rats. Pharmacol. Biochem. Behav. 46:631-636; 1993.
21. McBride, W. J.; Guan, X.-M.; Chernet, E.; Lumeng, L.; Li, T.-K.: Regional serotonin-1A receptors in the CNS of alcohol-preferring and -nonpreferring rats. Pharmacol. Biochem. Behav. 49:7-12; 1994.
22. McClearn, G. E.; Kakihana, R.: Selective breeding for ethanol sensitivity: Short-sleep and long-sleep mice. In: McClearn, G. E.; Deitrich, R. A.; Erwin, V. G., eds. Development of animal models as pharmacogenetic tools. NIAAA Research Monograph No. 6. Rockville, MD: NIAAA; 1981:147-159
23. McIntyre, T. D.; Trullas, R.; Skolnick, P.: Differences in the biophysical properties of the benzodiazepine/γ-aminobutyric acid receptor chloride channel complex in the long-sleep and short-sleep mouse lines. J. Neurochem. 51:642-647; 1988.
24. McQuilkin, S. J.; Harris, R. A.: Factors affecting actions of ethanol on GABA activated chloride channels. Life Sci. 46:527-541; 1990.
25. Mennini, T.; Gobbi, M.: Regional distribution of low-affinity GABA receptors coupled to benzodiazepine receptor subtypes in rat brain: An autoradiographic evaluation. Eur. J. Pharmacol. 189:143-148; 1990.
26. Montpied, P.; Weizman, A.; Weizman, R.; Kook, K. A.; Morrow, A. L.; Paul, S. M.: Repeated swim-stress reduces GABAA receptor subunit mRNAs in the mouse hippocampus. Mol. Brain Res. 18:267-272; 1993.
27. Morrow, A. L.; Suzdak, P. D.; Paul, S. M.: Benzodiazepine, barbiturate, ethanol and hypnotic steroid modulation of GAB A-mediated chloride ion transport in rat brain synaptoneurosomes. Adv. Biochem. Psychopharmacol. 45:247-261; 1988.
28. Nishio, M.; Narahashi, T.: Ethanol enhancement of GABA-activated chloride current in rat dorsal root ganglion neurons. Brain Res. 518:283-286; 1990.
29. Paxinos, G.; Watson, C.: The rat brain in stereotaxic coordinates. New York: Academic Press; 1986.
30. Pritchett, D. B.; Lüddens, H.; Seeburg, P. H.: Type I and type II GABAA-benzodiazepine receptors produced in transfected cells. Science 245:1389-1392; 1989.
31. Pritchett, D. B.; Sontheimer, H.; Shivers, B. D.; Ymer, S.; Kettenmann, H.; Schofield, P. R.; Seeburg, P. H.: Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature 338:582-585; 1989.
32. Sigel, E.; Baur, R.; Trube, G.; Mohler, H.; Malherbe, P.: The effect of subunit composition of rat brain GABAA receptors on channel function. Neuron 5:703-711; 1990.
33. Stewart, R. B.; Gatto, G. J.; Lumeng, L.; Li, T.-K.; Murphy, J. M.: Comparison of alcohol-preferring and -nonpreferring NP rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol 10:1-10; 1993.
34. Suzdak, P. D.; Schwartz, R. D.; Skolnick, P.; Paul, S. M.: Ethanol stimulates γ-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes. Proc. Natl. Acad. Sci. USA 83:4071-4075; 1986.
35. Thielen, R. J.; McBride, W. J.; Lumeng, L.; Li, T.-K.: Housing conditions alter GABAA receptor of alcohol-preferring and -non-preferring rats. Pharmacol. Biochem. Behav. 46:723-727; 1993.
36. Wafford, K. A.; Bain, C. J.; Whiting, P. J.; Kemp, J. A.: Functional comparison of the role of γ subunits in recombinant human γ-aminobutyric acidA/benzodiazepine receptors. Mol. Pharmacol. 44:437-442; 1993.
37. 2 subunit. FEBS Lett. 313:113-117; 1992.
38. Wafford, K. A.; Whiting, P. J.; Kemp, J. A.: Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant γ-aminobutyric acidA receptor subtypes. Mol. Pharmacol. 43: 240-244; 1992.
39. Waller, M. B.; McBride, W. J.; Lumeng, L.; Li, T.-K.: Initial sensitivity and acute tolerance to ethanol in the P and NP lines of rats. Pharmacol. Biochem. Behav. 19:683-686; 1983.
40. Waller, M. B.; Murphy, J. M.; McBride, W. J.; Lumeng, L.; Li, T.-K.: Effect of low dose ethanol on spontaneous motor activity in alcohol-preferring and -nonpreferring lines of rats. Pharmacol. Biochem. Behav. 24:617-623; 1986.
41. Weight, F. F.; Aguayo, L. G.; White, G.; Lovinger, D. M.; Peoples, R. W.: GABA- and glutamate-gated ion channels as molecular sites of alcohol and anesthetic action. Adv. Biochem. Psychopharmacol. 47:335-347; 1992.
42. Zhou, F. C.; Bledsoe, S.; Lumeng, L.; Li, T.-K.: Immunostained serotonergic fibers are decreased in selected brain regions of alcohol-preferring rats. Alcohol 8:425-431; 1991.
43. Zhou, F. C.; Bledsoe, S.; Lumeng, L.; Li, T.-K.: Reduced serotonergic immunoreactive fibers in the forebrain of alcohol-preferring rats. Alcohol. Clin. Exp. Res. 18:571-579; 1994.