Inhibition by β-carotene and astaxanthin of NADPH-dependent microsomal phospholipid peroxidation

Journal of Nutritional Science and Vitaminology

Volumn 43, Issue 3, 1997, Pages 345-355

  Nakagawa, Kiyotaka ^a   Kang, Sung Do ^b   Park, Dong Ki ^b   Handelman, Garry J ^c   Miyazawa, Teruo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Konkuk University   (South Korea)

^c TUFTS UNIVERSITY   (United States)

Author keywords

Antioxidant; Astaxanthin; Lipid peroxidation; Microsomes; Carotene

Indexed keywords

ADENOSINE DIPHOSPHATE; ALPHA TOCOPHEROL; ASTAXANTHIN; BETA CAROTENE; CAROTENOID; IRON; LIPID HYDROPEROXIDE; PHOSPHOLIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; LIVER MICROSOME; MALE; MICROSOME MEMBRANE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALIA;

EID: 0030762691     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.43.345     Document Type: Article

References (35)

1. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. 1989. Beyond cholesterol: Modifications of low density lipoprotein that increase its atherogenicity. N Engl J Med 320 915-924.
2. Nagano Y, Arai H, Kita T. 1991. High density lipoprotein loses its effect to stimulate efflux of cholesterol from foam cells after oxidative modification. Proc Natl Acad Sci USA 88: 6457-6461.
3. Esterbauer H, Gebicki J, Puhl H, Jurgens G. 1992. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Rad Biol Med 13: 341-390.
4. Miyazawa T, Fujimoto K, Oikawa S. 1990. Determination of lipid hydroperoxides in low density lipoprotein from human plasma using high performance liquid chromatography with chemiluminescence detection. Biomed Chromatogr 4: 131-134.
5. Harman D. 1981. The aging process. Proc Natl Acad Sci USA 78: 7124-7128.
6. Miyazawa T, Suzuki T, Fujimoto K. 1993. Age-dependent accumulation of phosphatidylcholine hydroperoxide in the brain and liver of the rat. Lipids 28: 789-793.
7. Suzuki T, Miyazawa T, Fujimoto K, Otsuka M, Tsutsumi M. 1993. Age-related accumulation of phosphatidylcholine hydroperoxide in cultured human diploid cells and its prevention by α-tocopherol. Lipids 28: 775-778.
8. Zhang J-R, Andrus PK, Hall ED. 1994. Age-related phospholipid hydroperoxide levels in gerbil brain measured by HPLC-chemiluminescence and their relation to hydroxyl radical stress. Brain Res 639: 275-282.
9. Miyazawa T, Suzuki T, Fujimoto K, Kinoshita M. 1996. Age-related change of phosphatidylcholine hydroperoxide and phosphatidylethanolamine hydroperoxide levels in normal human red blood cells. Mech Age Devel 86: 145-150.
10. Granger DN, Rutili G, McCord JM. 1981. Superoxide radicals in feline intestinal ischemia. Gastroenterology 81: 22-29.
11. Takayama F, Egashira T, Kudo Y, Yamanaka Y. 1992. Chemiluminescence HPLC assay of phosphatidylcholine hydroperoxide generated by ischemia-reperfusion in the liver of rats. Biochem Pharmacol 44: 2412-2414.
12. Verkleij AJ, Zwaal RFA, Roelofsen B, Comfurius P, Kastelijn D, Van Deenen LLM. 1973. The asymmetric distribution of phospholipids in the human red cell membrane. Biochim Biophys Acta 323: 178-193.
13. Higgins JA, Dawson RMC. 1977. Asymmetry of the phospholipid bilayer of rat liver endoplasmic reticulum. Biochim Biophys Acta 470: 342-356.
14. Dominski J, Binaglia L, Dreyfus H, Massarelli R, Mersel M, Freysz L. 1983. A study on the topological distribution of phospholipids in microsomal membranes of chick brain using phospholipase C and trinitrobenzenesulfonic acid. Biochim Biophys Acta 734: 257-266.
15. Miyazawa T. 1993. Membrane phospholipid hydroperoxides as estimated by chemiluminescence: the effect of dietary polyunsaturated fatty acids. In: Essential Fatty Acids and Eicosanoids. (Sinclair A, Gibon R, eds), p. 383-388. Am. Oil Chem. Soc., Champaign, IL, USA.
16. Palozza P, Krinsky NI. 1992. Antioxidant effect of carotenoids in vitro and in vivo: an overview. Methods Enzymol 213: 403-420.
17. Burton GW, Ingold KU. 1984. β-Carotene: an unusual type of lipid antioxidant. Science 224: 569-573.
18. Kennedy TA, Liebler DC. 1992. Peroxyl radical scavenging by β-carotene in lipid bilayers. J Biol Chem 267: 4658-4663.
19. Palozza P, Moualla S, Krinsky, NI. 1992. Effects of β-carotene and α-tocopherol on radical-initiated peroxidation of microsomes. Free Rad Biol Med 13: 127-136.
20. Palozza P, Krinsky NI. 1992. Astaxanthin and canthaxanthin are potent antioxidants in a membrane model. Arch Biochem Biophys 297: 291-295.
21. Miyazawa T, Yasuda K, Fujimoto K. 1987. Chemiluminescence-high performance liquid chromatography of phosphatidylcholine hydroperoxide. Anal Lett 20: 915-925.
22. Miyazawa T, Suzuki T, Fujimoto K, Yasuda K. 1992. Chemiluminescent simultaneous determination of phosphatidylcholine hydroperoxide and phosphatidylethanolamine hydroperoxide in the liver and brain of the rat. J Lipid Res 33: 1051-1059.
23. Miyazawa T, Fujimoto K, Suzuki T, Yasuda K. 1994. Determination of phospholipid hydroperoxides using luminol chemiluminescence-high-performance liquid chromatography. Methods Enzymol 233: 324-332.
24. Okada Y, Harano T. 1984. Microsomes. In: Experimental Biology Course (Mori H, Kagawa Y, eds), Vol. VI, p. 54-55. Maruzen, Tokyo (in Japanese).
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275.
26. Svingen BA, Buege JA, O'Neal FO, Aust SD. 1979. The mechanism of NADPH-dependent lipid peroxidation. J Biol Chem 254: 5892-5899.
27. Buege J, Aust SD. 1978. Microsomal lipid peroxidation. Methods Enzymol 52: 302-310.
28. Stahl W, Sundquist AR, Hanusch M, Schwarz W, Sies H. 1993. Separation of β-carotene and lycopene geometrical isomers in biological samples. Clin Chem 39: 810-814.
29. Barua AB, Furr HC. 1992. Extraction and analysis by high-performance liquid chromatography of carotenoids in human serum. Methods Enzymol 213: 273-281.
30. Nakagawa K, Fujimoto K, Miyazawa T. 1996. β-Carotene as a high-potency antioxidant to prevent the formation of phospholipid hydroperoxides in red blood cells of mice. Biochim Biophys Acta 1299: 110-116.
31. Johansson LB, Lindblom G, Wieslander A, Arvidson G. 1981. Orientation of β-carotene and retinal in lipid bilayers. FEBS Lett 128: 97-99.
32. Milan A, Wolff G, Ourisson G, Nakatani Y. 1986. Incorporation of zeaxanthin, astaxanthin and their C50 homologues into dimyristoylphosphatidylcholine vesicles. Helv Chim Acta 69: 12-24.
33. Palozza P, Krinsky NI. 1991. The inhibition of radical-initiated peroxidation of microsomal lipids by both α-tocopherol and β-carotene. Free Rad Biol Med 11: 407-414.
34. Mayne ST, Parker RS. 1989. Antioxidant activity of dietary canthaxanthin. Nutr Cancer 12: 225-236.
35. Someya K, Totsuka Y, Murakoshi M, Kitano H, Miyazawa T. 1994. The antioxidant effect of palm fruit carotene on skin lipid peroxidation in guinea pigs as estimated by chemiluminescence-HPLC method. J Nutr Sci Vitaminol 40: 315-324.