Effect of clavulanic acid and/or polymorphonuclear neutrophils on amoxicillin bactericidal activity against Streptococcus pneumoniae

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 16, Issue 7, 1997, Pages 512-516

  Martin M ^a   Gomez Lus M L ^a   Aguilar, L ^b   Martinez P ^a   Gimenez M J ^b   Prieto, J ^a  

^a SCHOOL OF MEDICINE   (Spain)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; CLAVULANIC ACID; PENICILLIN G;

ARTICLE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; HUMAN CELL; IMMUNITY; MINIMUM INHIBITORY CONCENTRATION; NEUTROPHIL; NONHUMAN; PENICILLIN RESISTANCE; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; STREPTOCOCCUS PNEUMONIAE;

AMOXICILLIN; AMPICILLIN RESISTANCE; BETA-LACTAMASES; CLAVULANIC ACID; ENZYME INHIBITORS; HUMANS; MICROBIAL SENSITIVITY TESTS; NEUTROPHILS; PENICILLINS; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS;

EID: 0030762661     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01708234     Document Type: Article

References (22)

1. Van den Broek PJ, Seymonsbergen EM: The influence of human granulocytes and monocytes on the antibacterial activity of cefetamet against Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 1995, 35: 611-622.
2. Veringa EM, Verhoef J: Clindamycin at sub-inhibitory concentrations enhances antibody and complement dependent phagocytosis by human polymorphonuclear leukocytes of Staphylococcus aureus. Chemotherapy 1987, 33: 243-249.
3. Daschner FD: Antibiotics and host defence with special reference to phagocytosis by human polymorphonuclear leukocytes. Journal of Antimicrobial Chemotherapy 1985, 16: 390-396.
4. Milatovic D: Antibiotics and phagocytosis. European Journal of Clinical Microbiology 1983, 2: 414-425.
5. Anderson R, Joone G, van Rensburg CEJ: An in vitro investigation of the intracellular bioactivity of amoxicillin, clindamycin, and erythromycin for Staphylococcus aureus. Journal of Infectious Diseases 1986, 153: 593-600.
6. Cartwright SJ, Coulson AFW: A semi-synthetic penicillinase inactivator. Nature 1979, 278: 360-361.
7. Pascual A, Martínez L, Aragón J, Perea EJ: Effect of amoxycillin and clavulanic acid, alone and in combination, on human polymorphonuclear leukocyte function against Staphylococcus aureus. European Journal of Clinical Microbiology & Infectious Diseases 1989, 8: 277-281.
8. Friedland IR, McCracken Jr GH: Management of infections caused by antibiotic-resistant Streptococcus pneumoniae. New England Journal of Medicine 1994, 331: 377-382.
9. Eggleton P, Gargan R, Fisher D: Rapid method for the isolation of neutrophils in high yield without the use of dextran or density gradient polymers. Journal of Immunology Methods 1989, 121: 105-113.
10. Adam D, De Visser I, Koeppe P: Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination. Antimicrobial Agents and Chemotherapy 1982, 22: 353-357.
11. Fraschini F, Scaglione F, Falchi M, Dugnani S, Mezzetti M, Cicchetti F, Alfano G, Pintucci GP: Pharmacokinetics and tissue distribution of amoxicillin plus clavulanic acid after oral administration in man. Journal of Chemotherapy 1990, 2: 171-177.
12. Amsterdam D: The MIC: myth and reality. Antimicrobic Newsletter 1992, 8: 9-16.
13. Amsterdam D: Assessing cidal activity of antimicrobial agents: problems and pitfalls. Antimicrobic Newsletter 1990, 7: 49-56.
14. Gerberding JL, Sande MA: Limitations of animal models in predicting beta-lactam efficacy for endocarditis and meningitis. Reviews of Infectious Diseases 1986, 8, Supplement 3: 315-318.
15. Mattie H: Kinetics of antimicrobial action. Reviews of Infectious Diseases 1981, 3: 19-27.
16. Lorian V, Gemmell CG: Effect of low antibiotic concentrations on bacteria: effects on ultrastructure, virulence, and susceptibility to immunodefenses. In: Lorian V (ed): Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, 1991, p. 493-555.
17. Tuomanen E: Phenotypic tolerance: the search for beta-lactam antibiotics that kill nongrowing bacteria. Reviews of Infectious Diseases 1986, 8, Supplement 3: 279-291.
18. Gillissen G, Hasse G1 L'acide clavulanique. Son effet sur le staphylocoque dore outre l'effet inhibiteur sur les betalactamases. Pathology and Biology 1987, 35: 503-506.
19. Martín M, Aguilar L, Balcabao IP, Gómez-Lus ML, DalRé R, Prieto J: In-vitro pharmacodynamic simulation of clavulanic acid concentrations: effect on Staphylococcus aureus and Haemophilus influenzae β-lactamase activity. Journal of Antimicrobial Chemotherapy 1997, 39: 290-292,
20. Severin A, Severina E, Tomasz A: Abnormal physiological properties and altered cell wall composition in Streptococcus pneumoniae grown in the presence of clavulanic acid. Antimicrobial Agents and Chemotherapy 1997, 41: 504-510.
21. Lepper MH, Dowling HF: Treatment of pneumococcic meningitis with penicillin compared with penicillin plus aureomycin: studies including observations on an apparent antagonism between penicillin and aureomycin. Archives of Internal Medicine 1951, 88: 489-494.
22. Gómez-Lus ML, Aguilar L, Martín M, Giménez MJ, Martínez P, Prieto J: Intracellular and extracellular killing of a penicillin-resistant, serotype-9 strain of Streptococcus pneumoniae by polymorphonuclear leucocytes in the presence of sub-inhibitory concentrations of clavulanic acid. Journal of Antimicrobial Chemotherapy 1997, 40: 142-144.