Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia

Biophysical Journal

Volumn 73, Issue 4, 1997, Pages 1913-1924

  Laver, D R ^a   Owen, V J ^b   Junankar, P R ^a   Taske, N L ^a   Dulhunty, A F ^a   Lamb, G D ^b  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CALCIUM ION; CESIUM; HALOTHANE; MAGNESIUM ION; RYANODINE RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; IONIC STRENGTH; LIPID BILAYER; MALIGNANT HYPERTHERMIA; MEMBRANE VESICLE; MUSCLE CONTRACTURE; NONHUMAN; SKELETAL MUSCLE; SWINE;

ANIMALIA; SUS SCROFA;

EID: 0030762326     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78222-5     Document Type: Article

References (44)

1. Ahern, G. P., P. R. Junankar, and A. F. Dulhunty. 1997. Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12. Biophys. J. 72:146-162.
2. 2+. Biophys. J. 72:A274.
3. Bhat, M. B., J. Zhao, S. Hayek, E. C. Freeman, H. Takeshima, and J. Ma. 1997. The negatively charged D3 region of skeletal muscle ryanodine receptor is involved in ion conduction and Ca-dependent inactivation of the Ca release channel. Biophys. J. 72:A169.
4. 2+ release from sarcoplasmic reticulum of malignant hyperthermia susceptible pigs. Biochem. Biophys. Acta. 1064:175-183.
5. El-Hayek, R., M. Yano, B. Antoniu, J. R. Mickelson, C. F. Louis, and N. Ikemoto. 1995. Altered E-C coupling in triads isolated from malignant hyperthermia-susceptible porcine muscle. Am. J. Physiol. 268: 1381-1386.
6. Fatatsugi, A., G. Kuwajima, and K. Mikoshiba. 1995. Tissue-specific and developmentally regulated alternative splicing in mouse skeletal muscle ryanodine receptor mRNA. Biochem. J. 305:373-378.
7. Fill, M., R. Coronado, J. R. Mickelson, J. Vilven, J. Ma, B. A. Jacobson, and C. F. Louis. 1990. Abnormal ryanodine receptor channels in malignant hyperthermia. Biophys. J. 50:471-175.
8. 2+-dependent ATPase activity on malignant hyperpyrexia-susceptible porcine skeletal muscle. Clin. Exp. Pharmacol. Physiol. 18:489-495.
9. Gallant, E. M., and L. R. Lentz. 1992. Excitation-contraction coupling in pigs heterozygous for malignant hyperthermia. Am. J. Physiol. 262: 422-426.
10. Hain, J., S. Nath, M. Mayrleitner, S. Fleischer, and H. Schindler. 1994. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from skeletal muscle. Biophys. J. 67: 1832-1833.
11. Iaizzo, P. A., W. Klein, and F. Lehmann-Horn. 1988. Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs. Pflügers Arch. 411:648-653.
12. 2+ inhibition and malignant hyperthermia. J. Muscle Res. Cell Motil. 14:554-556.
13. 2+ release in skeletal muscle fibres of the toad. J. Physiol. (Lond.). 434:507-528.
14. 2+ in excitation-contraction coupling in skeletal muscle. News Physiol. Sci. 7:270-274.
15. 2+] on excitation-contraction coupling in skeletal muscle fibres of the rat. J. Physiol. (Lond.). 478:331-339.
16. Laver, D. R., T. M. Baynes, and A. F. Dulhunty. 1997. Magnesium-inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanisms. J. Membr. Biol. 156:213-229.
17. 2+ steps produced by rapid solution exchange. Biophys. J. 71:732-741.
18. 2+ inhibits the ryanodine receptor from cardiac muscle. J. Membr. Biol. 147:7-22.
19. 2+-selective microelectrodes. Arch. Biochem. Biophys. 247:294-301.
20. Ma, J., M. B. Bhat, and J. Zhao. 1995. Rectification of skeletal muscle ryanodine receptor mediated by FK506 binding protein. Biophys. J. 69:2398-2404.
21. MacLennan, D. H., and M. S. Phillips. 1992. Malignant hyperthermia. Science. 256:789-794.
22. 2+ release in sarcoplasmic reticulum. J. Biol. Chem. 259:2365-2374.
23. 2+ release channels and their regulation by endogenous effectors. Annu. Rev. Physiol. 56:485-508.
24. 2+, and adenine nucleotides. Biochemistry. 25:236-244.
25. 2+ and monovalent cations and anions. J. Biol. Chem. 272:1628-1638.
26. 3H]ryanodine binding to sarcoplasmic reticulum from malignant hyperthermia susceptible pigs. Arch. Biochem. Biophys. 278:251-257.
27. 2+ regulation defects. Physiol. Rev. 76:538-592.
28. ++-induced fusion of fragmented sarcoplasmic reticulum with artificial planar bilayers. Cell. 9:283-300.
29. Mueller, P., D. O. Rudin, H. C. Tien, and W. C. Westcott. 1962. Reconstitution of cell membrane structure in vitro and its transformation into an excitable system. Nature. 194:979-981.
30. Nagura, S., T. Kawasaki, T. Taguchi, and M. Kasai. 1988. Calcium release from isolated sarcoplasmic reticulum due to 4,4′-dithiodipyridine. J. Biochem. 104:461-465.
31. O'Brien, P. J. 1986. Porcine malignant hyperthermia susceptibility: hypersensitive calcium-release mechanism of skeletal muscle sarcoplasmic reticulum. Can. J. Vet. Res. 50:318-328.
32. Ohta, T., M. Endo, T. Nakano, Y. Morohoshi, K. Wanikawa, and A. Ohga. 1989. Ca-induced Ca release in malignant hyperthermia-susceptible pig skeletal muscle. Am. J. Physiol. 256:C358-C367.
33. Otsu, K., M. S. Phillips, V. K. Khanna, S. De Leon, and D. H. MacLennan. 1992. Refinement of diagnostic assays for a probable causal mutation for porcine and human malignant hyperthermia. Genomics. 13:835-837.
34. 2+ release in muscle fibres of pigs susceptible to malignant hyperthermia. Am. J. Physiol. 272:203-211.
35. 2+ release channel. Biophys. J. 68:A173.
36. Shomer, N. H., C. F. Louis, M. Fill, L. A. Litterer, and J. R. Mickelson. 1993. Reconstitution of abnormalities in the malignant hyperthermia-susceptible pig ryanodine receptor. Am. J. Physiol. 264:125-135.
37. 2+ release channel. Am. J. Physiol. 267:1235-1261.
38. 615 mutation. Biophys. J. 67:641-646.
39. Smith, J. S., T. Imagawa, J. Ma, M. Fill, K. P. Campbell, and R. Coronado. 1988. Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum. J. Gen. Physiol. 92:1-26.
40. 2+ release channel in junctional sarcoplasmic reticulum: gating and blockade by cations. Int. J. Biochem. 24:903-909.
41. Timerman, A. P., E. Ogunbumni, E. Freund, G. Wiederrech, A. R. Marks, and S. Fleischer. 1993. The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. J. Biol. Chem. 268:22992-22999.
42. Tinker, A., and A. J. Williams. 1992. Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum. J. Gen. Physiol. 100:479-493.
43. 2+. Biophys. J. 70:2600-2615.
44. 2+ release channel (ryanodine receptor). Biophys. J. 69:106-119.