Inhibition of human tumour cell proliferation by analogues of adenosine

Cell Biochemistry and Function

Volumn 15, Issue 2, 1997, Pages 135-139

  Colquhoun, Alison ^a,b   Newsholme, Eric A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Adenosine analogues; Proliferation; Tumour

Indexed keywords

6 N CYCLOPENTYLADENOSINE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE DERIVATIVE; DNA; PHENYLISOPROPYLADENOSINE;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL;

ANIMALIA;

EID: 0030761852     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1099-0844(19970601)15:2<135::aid-cbf733>3.0.co;2-g     Document Type: Article

References (31)

1. Fredholm, B. B. and Sollevi, A. (1986). Cardiovascular effects of adenosine Clin. Physiol., 6, 1-21.
2. Fox, I. H. and Kelley. W. N. (1978). The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu. Rev. Biochem., 47, 655-686.
3. Hourani, S. M. O. and Cusack, N. J. (1991). Pharmacological receptors on blood platelets. Pharmacol. Rev., 43, 243-298.
4. Sollevi, A., Torssell, L., Owall, A , Edlund, A. and Lager Kranser, M. (1986). Levels and cardiovascular effects of adenosine in humans. In: Topics and Perspectives in Adenosine Research (Gerlach, E. and Becker. B. G., eds.) Springer-Verlag: Berlin, pp. 599-613.
5. Schwabe, U., Ebert, E. and Erbler, H. C. (1975) Adenosine release from fat cells: effect on cyclic AMP levels and hormone actions. Adv. Cyclic Nucleotide Res., 5, 569-584.
6. Arch, J. R. and Newshoime, E. A. (1978). The control of the metabolism and the hormonal role of adenosine Essays Biochem., 14, 82-123.
7. Londos, C., Cooper, D. M. and Wolff, J. (1980). Subclasses of external adenosine receptors. Proc. Natl. Acad. Sci. U.S.A., 77, 2551-2554.
8. Londos, C. and Wolff, J. (1977). Two distinct adenosine-sensitive sites on adenylate cyclase. Proc. Natl. Acad Sci. U.S.A., 74, 5482-5486.
9. Daly, J. W., Bruns, R. F. and Snyder, S. H. (1981). Adenosine receptors in the central nervous system: relationship to the central actions of methylxanthines. Life Sci., 28, 2083-2097.
10. Van Calker, D., Muller, M. and Hamprecht, B. (1979). Adenosine regulates via two different types of receptors; the accumulation of cyclic AMP in cultured brain cells. J. Neurochem., 33, 999-1005
11. Pastan, I. H., Johnson, G. S. and Anderson, W. B. (1975). Role of cyclic nucleotides in growth control. Annu. Rev. Biochem., 44, 491-522.
12. Dumont, J, E., Jauniaux, J. C. and Roger, P. P. (1989). The cyclic AMP-mediated stimulation of cell proliferation. TIBS, 14, 67-71.
13. 3H]N6-phenylisopropyladenosine. Nauyn Schmiedebergs Arch. Pharmacol., 313, 179-187.
14. Hutchison, K. A. and Fox, I. H. (1989). Purification and characterization of the adenosine A2-like binding site from human placental membrane. J. Biol. Chem., 264, 19898-19903.
15. Fredholm, B. B. (1982). Adenosine receptors. Med. Biol., 60, 289-293.
16. Ardawi, M. S. M. and Newsholme, E. A. (1982). Maximal activities of some enzymes of glycolysis, the tricarboxylic acid cycle, ketone body and glutamine utilization pathways in lymphocytes of the rat. Biochem. J., 208, 743-748.
17. Schultz, L. A., Kammer, G. M. and Rudolph, S. A. (1988). Characterization of the human T lymphocyte adenosine receptor: comparison of normal and systemic erythematosus cells. FASEB J., 2, 244-250.
18. Kammer, G. M. (1988). The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol. Today, 9, 222-229.
19. Eagle, H. (1959). Amino acid metabolism in mammalian cells Science, 130, 432-437.
20. Weber, G. (1983) Biochemical strategy of cancer cells and the design of chemotherapy. Cancer Res., 43, 3466-3492.
21. Denton, J. E., Lui, M. S., Aoki, T., Sebolt, J., Takada, E., Eble, J. N., Glover, J. L. and Weber, G. (1982). Enzymology of pyrimidine and carbohydrate metabolism in human colon carcinomas. Cancer Res., 42, 1176-1183
22. Natsumeda, Y., Lui, M. S., Emrani, J., Faderman, M. A., Reardon, M. A., Eble, J. N., Glover, J. L. and Weber, G. (1985). Purine enzymology of human colon carcinomas. Cancer Res., 45, 2556-2559.
23. Moos, W. H., Szotek, D. S. and Bruns, R. F. (1985). N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists. J. Med. Chem., 28, 1383-1384.
24. 3H]NECA in rat striatal membranes. Mol. Pharmacol., 29, 331-346.
25. Trivedi, B. K., Bridges, A. J., Patt, W. C., Priebe, S. R. and Brun, R. F. (1989). N6-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor. J. Med. Chem., 32, 8-11.
26. Delahunty, T. M., Cronin, M. J. and Linden, J. (1988). Regulation GH3-cell function via adenosine A1 receptors. Inhibition of prolactin release, cyclic AMP production and inositol phosphate generation. Biochem. J., 255, 69-77.
27. Ohigashi, T., Brookins, J. and Fisher, J. W. (1993). Adenosine AI receptors and erythropoietin production. Am. J. Physiol., 265, C934-C938.
28. Nordstedt, C., Kvanta, A., Van der Ploeg, I. and Fredholm, B. B. (1989). Dual effects of protein kinase-C on receptor stimulated cAMP accumulation in a human T-cell leukaemia line. Eur. J. Pharmacol., 172, 51-60.
29. Daly, J. W. (1985). Adenosine receptors Adv. Cyclic. Nucleotide Protein Phosphorylaiton Res., 19, 29-46.
30. Challiss, R. A., Richards, S. J. and Budohoski, L. (1992). Characterization of the adenosine receptor modulating insulin action in rat skeletal muscle. Eur. J. Pharmacol., 226, 121-128.
31. Reaven, G. M., Chang, H., Ho, H., Jeng, C. Y. and Hoffman, B. B. (1988). Lowering of plasma glucose in diabetic rats by anitipolytic agents. Am. J. Physiol., 254, E23-E30.