Carotenoids and intercellular communication via gap junctions

International Journal for Vitamin and Nutrition Research

Volumn 67, Issue 5, 1997, Pages 364-367

  Sies, Helmut ^a   Stahl, Wilhelm ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

4 oxo Retinoic acid; Carotenoids; Connexin; Gap junctions; Intercellular communication; Retinoids; Structure

Indexed keywords

CAROTENOID;

ANIMAL; ARTICLE; CELL COMMUNICATION; CELL JUNCTION; CHEMISTRY; HUMAN; PHYSIOLOGY;

ANIMALS; CAROTENOIDS; CELL COMMUNICATION; GAP JUNCTIONS; HUMANS;

ANIMALIA;

EID: 0030760599     PISSN: 03009831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Goodenough, D. A., Goliger, J. A. and Paul, D. L. (1996) Connexins, connexons and intercellular communication. Annu. Rev. Biochem. 65, 475-502.
2. Kolb, H.-A. and Somogyi, R. (1991) Biochemical and biophysical analysis of cell-to-cell channels and regulation of gap junctional permeability. Rev. Physiol. Biochem. Pharmacol. 118, 1-47.
3. Peracchia, C. (1980) Structural correlates of gap junction permeation. Int. Rev. Cytol. 66, 81-139.
4. Hall, J. E., Zampighi, G. A. and Davis, R. M. (Eds.) (1993) Gap junctions. Elsevier, New York.
5. Holder, J. W., Elmore, E. and Barrett, J. C. (1993) Gap junction function and cancer. Cancer Res. 53, 3475-3485.
6. Hotz-Wagenblatt, A. and Shalloway, D. (1993) Gap junctional communication and neoplastic transformation. Crit. Rev. Oncogen. 4, 541-558.
7. Yamasaki, H. (1995) Non-genotoxic mechanisms of carcinogenesis: studies of cell transformation and gap junctional intercellular communication. Toxicol. Lett. 77, 55-61.
8. Krutovskikh, V. A., Mesnil, M., Mazzoleni, G. and Yamasaki, H. (1995) Inhibition of rat liver gap junction intercellular communication by tumor promoting agents in vivo. Lab. Invest. 72, 571-577.
9. Budunova, I. V. and Williams, G. M. (1994) Cell culture assays for chemicals with tumor-promoting or tumor-inhibiting activity based on the modulation of intercellular communication. Cell Biol. Toxicol. 10, 71-116.
10. Hossain. M. Z., Zhang, L.-X. and Bertram, J. S. (1993) Retinoids and carotenoids upregulate gap-junctional communication: correlation with enhanced growth control and cancer prevention. Progr. Cell Res. 3, 301-309.
11. Wolf, G. (1992) Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication. Nutr. Rev. 50, 270-274.
12. Pung, A., Rundhaug, J. E., Yoshizawa, C. N. and Bertram, J. S. (1988) β-Carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis 9, 1533-1539.
13. Pung, A., Franke, A., Zhang, L.-X., Ippendorf, M., Martin, H.-D., Sies, H. and Bertram, J. S. (1993) A synthetic C22 carotenoid inhibits carcinogen-induced neoplastic transformation and enhances gap junctional communication. Carcinogenesis 14, 1001-1005.
14. Hossain, M. Z. and Bertram, J. S. (1994) Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells, implications for the role of gap junctional communication. Cell Growth Different. 5, 1253-1261.
15. Yamasaki, H., Krutovskikh, V. A., Mesnil, M., Columbano, A., Tsuda, H. and Ito, N. (1993) Gap junctional intercellular communication and cell proliferation during rat liver carcinogenesis. Environ. Health Perspect. 101, 191-198.
16. Dahl, E., Winterhager, E., Traub, O. and Willecke, K. (1995) Expression of gap junction genes, connexin40 and connexin43, during fetal mouse development. Anat. Embryol. 191, 267-278.
17. Allen, F. Tickle, C. and Warner, A. (1990) The role of gap junctions in patterning of the chick limb bud. Development 108, 623-634.
18. Steward, W. W. (1978) Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer. Cell 14, 741-759.
19. Zhang, L.-X., Cooney, R. V. and Bertram, J. S. (1991) Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer preventive action. Carcinogenesis 12, 2109-2114.
20. Stahl, W., Nicolai, S., Briviba, K., Hanusch, M., Broszeit, G., Peters, M., Martin, H.-D. and Sies, H. (1997) Biological activities of natural and synthetic carotenoids, induction of gap junctional communication and singlet oxygen quenching. Carcinogenesis, 18, 89-92.
21. Mesnil, M., Oyamada, M., Jongen, W. M. F. Krutovskikh, V. A. and Yamasaki, H. (1993) Gap junctional communication alterations at various levels of connexin expression and function during animal and human carcinogenesis. Progr. Cell Res. 3, 311-316.
22. Bex, V., Mercier, T., Chaumontet, C., Gaillard-Sanchez, I., Flechon, B., Mazet, F., Traub, O. and Martel, P. (1995) Retinoic acid enhances connexin43 expression at the post-transcriptional level in rat liver epithelial cells. Cell Biochem. Funct. 13, 69-77.
23. Leid, M., Kastner, P. and Chambon, P. (1992) Multiplicity generates diversity in the retinoic acid signalling pathways. TIBS 17, 427-433.
24. Mangelsdorf, D. J., Umesono, K. and Evans, R. M. (1994) The retinoid receptors. In: Retinoids, Biology, Chemistry and Medicine. (Sporn, M. B., Roberts, A. B. and Goodman, D. S., eds.) pp. 319-350. Raven Press, New York.
25. Hanusch, M., Stahl, W., Schulz, W. A. and Sies, H. (1995) Induction of gap junctional communication by 4-oxoretinoic acid generated from its precursor canthaxanthin. Arch. Biochem. Biophys. 317, 423-428.
26. Nikawa, T., Schulz, W. A., van den Brinck, C. E., Hanusch, M., van der Saag, P., Stahl, W. and Sies, H. (1995) Efficacy of all-trans-β-carotene, canthaxanthin and all-trans-, 9-cis- and 4-oxo-retinoic acids in inducing differentiation of an F9 embryonal carcinoma RARβ-lacZ reporter cell line. Arch. Biochem. Biophys. 316, 665-672.
27. Pijnapple, W. W. M., Hendriks, H. F. J., Folkers, G. E., van den Brink, C. E., Dekker, E. J., Edelenbosch, C., van der Saag, P. and Durston, A. J. (1993) The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification. Nature 366, 340-344.