Analysis of small hair bundles in the utricles of mature guinea pigs

American Journal of Otology

Volumn 18, Issue 5, 1997, Pages 637-643

  Lambert, Paul R ^a,b   Gu, Rende ^a   Corwin, Jeffrey T ^a  

^a UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Hair cell regeneration; Stereocilia; Utricle

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL METABOLISM; CELL REGENERATION; GUINEA PIG; HAIR CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; STEREOCILIUM; UTRICLE;

ANIMALS; GUINEA PIGS; HAIR CELLS; MICROSCOPY, ELECTRON; SACCULE AND UTRICLE;

EID: 0030760532     PISSN: 01929763     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Cotran RS, Kumar V, Robbins SL. Healing and repair. In: Robbins' pathologic basis of disease. Philadelphia: WB Saunders, 1989:71-86.
2. Ruben RJ. Development of the inner ear of the mouse: a radioautographic study of terminal mitosis. Acta Otolaryngol Suppl (Stockh) 1967;20:1-44.
3. Graziadei PPC, Monti Graziadei GA. Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons. J Neurocytol 1979:1-18.
4. Constanzo RM. Neural regeneration and functional reconnection following olfactory nerve transection in hamster. Brain Res 1985;361:258-66.
5. Warchol ME, Lambert PR, Goldstein BJ, et al. Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. Science 1993;259:1619-22.
6. Lambert PR. Inner ear hair cell regeneration in a mammal: identification of a triggering factor. Laryngoscope 1994;104:701-18.
7. Yamashita H, Oesterle EC. Induction of cell proliferation in mammalian inner-ear sensory epithelia by transforming growth factor α and epidermal growth factor. Proc Natl Acad 1995;92:3152-55.
8. Forge A, Li L, Corwin JT, et al. Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 1993;259: 1616-9.
9. Jorgensen JM, Mathiesen C. The avian inner ear. Continuous production of hair cells in vestibular organs, but not in the auditory papilla. Naturwissenschaften 1988;75:319-20.
10. Roberson DW, Weisleder P, Bohrer PS, et al. Ongoing production of sensory cells in the vestibular epithelium of the chick. Hear Res 1992;57:166-74.
11. Anniko M. Embryonic development of vestibular sense organs and their innervation. In: Romand R, ed. Development of auditory and vestibular systems. New York: Academic Press, 1983:375-423.
12. Lindeman HH. Studies on the morphology of the sensory regions of the vestibular apparatus. Adv Anat Embryol Cell Biol 1969;42: 1-110.
13. Lim DJ. Morphological and physiological correlates in cochlear and vestibular sensory epithelia. Scanning Electron Microscopy II (Part V) 1976:269-76.
14. Li CW. Hair cell development in the inner ear. Scanning Electron Microscopy 1978;11:967-74.
15. Favre D, Bagger-Sjöback D, Mbiene J-P, et al. Freeze-fracture study of the vestibular hair cell surface during development. Anat Embryol 1986;175:69-76.
16. Lapeyre P, Guilhaume A, Cazals Y. Differences in hair bundles associated with type I and type II vestibular hair cells of the guinea pig saccule. Acta Otolaryngol (Stockh) 1992;112:635-42.
17. Corwin JT. Postembryonic production and aging of inner ear hair cells in sharks. J Comp Neurol 1981;201:541-53.
18. Corwin JT. Postembryonic growth of the macula neglect auditory detector in the ray, raja clavata: continual increases in hair cell number, neural convergence and physiological sensitivity. J Comp Neurol 1983;217:345-56.
19. Corwin JT. Perpetual production of hair cells and maturational changes in hair cell ultrastructure accompany post-embryonic growth in an amphibian ear. Proc Natl Acad Sci USA 1985;82: 3911-5.
20. Popper AN, Hoxter B. Growth of a fish ear: 1. quantitative analysis of hair cell and ganglion cell proliferation. Hear Res 1984;15:133-42.
21. Corwin JT, Warchol ME, Saffer LD, et al. Growth factors as potential drugs for the sensory epithelia of the ear. Ciba Found Symp 1996;196:167-87.
22. Raphael Y, Miller JM. Dual mechanisms for production of new hair cells in regenerating avian cochlea. Society of Neuroscience Abstract 1991;17:1214.
23. Baird RA, Bales S, Fiorilla C, et al. In vivo and in vitro evidence for nonmitotic hair cell regeneration in the bullfrog vestibular otolith organs. Association for Research in Otolaryngology Abstract 1995;178:45.
24. Adler HJ, Raphael Y. New hair cells in the acoustically damaged chick inner ear following cytosine arabinoside application: In vivo evidence for supporting cell conversion. Assoc Res Otolaryngol Abstr 1995;179:45.
25. Sobkowics HM, August BK, Slapnik SM. Epithelial repair following mechanical injury of the developing organ of Corti: an electron microscopic and autoradiographic study. Exp Neurol 1992;44: 44-9.
26. Rubel EW, Dew LA, Roberson DW. Mammalian vestibular hair cell regeneration. Science 1995;267:701-7.
27. Roberson DW, Kreig CS, Rubel EW. Light microscopic evidence that direct transdifferentiation gives rise to new hair cells in regenerating auditory epithelium. Auditory Neuroscience 1996; 2:195-205.
28. Rosenthal U. Degenerative patterns in the aging human vestibular neuro-epithelia. Acta Otolaryngol (Stockh) 1973;76: 208-20.