Pharmacological modulation of the mechanical response of airway smooth muscle to length oscillation

Journal of Applied Physiology

Volumn 83, Issue 3, 1997, Pages 739-745

  Shen, X ^a   Wu, M F ^a   Tepper, R S ^a   Gunst, S J ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Airway reactivity; Contractile mechanisms; Tidal breathing; Tracheal smooth muscle

Indexed keywords

ACETYLCHOLINE; CALCIUM; POTASSIUM CHLORIDE;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DOG; HYSTERESIS; LUNG VOLUME; MUSCLE ISOMETRIC CONTRACTION; MUSCLE LENGTH; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; RESPIRATORY TRACT MUCOSA;

EID: 0030760025     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.3.739     Document Type: Article

References (20)

1. 2 mobilization by muscarinic agonists in tracheal smooth muscle. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L53-L59, 1993.
2. Chalovich, J. M. Actin mediated regulation of muscle contraction. Pharmacol. Ther. 55: 95-148, 1992.
3. Fredberg, J. J., D. Bunk, E. Ingenito, and S. A. Shore. Tissue resistance and the contractile state of the lung parenchyma. J. Appl. Physiol. 74: 1387-1397, 1993.
4. Fredberg, J. J., K. A. Jones, M. Nathan, S. Raboudi, Y. S. Prakash, S.A. Shore, J. P. Butler, and G. C. Sieck. Friction in airway smooth muscle: mechanism, latch, and implications in asthma. J. Appl. Physiol. 81: 2703-2712, 1996.
5. Gunst, S. J. Contractile force of canine airway smooth muscle during cyclical changes in length. J. Appl. Physiol. 55: 759-769, 1983.
6. Gunst, S. J., M. H. Al-Hassani, and L. P. Adam. Regulation of isotonic shortening velocity by second messengers in tracheal smooth muscle. Am. J. Physiol. 266 (Cell Physiol. 35): C684-C691, 1994.
7. 2+ sensitivity of contractile activation during muscarinic stimulation of tracheal muscle. Am. J. Physiol. 263 (Cell Physiol. 32): C1258-C1265, 1992.
8. Gunst, S. J., R. Meiss, and M. F. Wu, and M. A. Rowe. Mechanisms for the mechanical plasticity of tracheal smooth muscle. Am. J. Physiol. 268 (Cell Physiol. 37): C1267-C1276, 1995.
9. Gunst, S. J., J. Q. Stropp, and N. A. Flavahan. Muscarinic receptor reserve and β-adrenergic sensitivity in tracheal smooth muscle. J. Appl. Physiol. 67: 1294-1298, 1989.
10. Gunst, S. J., J. Q. Stropp, and J. Service. Mechanical modulation of pressure-volume characteristics of canine airways in vitro. J. Appl. Physiol. 68: 2223-2229, 1990.
11. Gunst, S. J., M. F. Wu, and D. D. Smith. Contraction history modulates isotonic shortening velocity in smooth muscle. Am. J. Physiol. 264 (Cell Physiol. 33): C467-C476, 1993.
12. Mehta, D., M. F. Wu, and S. J. Gunst. Ca sensitivity of tyrosine phosphorylation of paxillin and myosin light chain phosphorylation in β-escin permeabilized canine tracheal smooth muscle (Abstract). Biophys. J. 72: A177, 1997.
13. Pavalko, F. M., L. P. Adam, M. F. Wu, T. L. Walker, and S. J. Gunst. Phosphorylation of dense plaque proteins talin and paxillin during tracheal smooth muscle contraction. Am. J. Physiol. 268 (Cell Physiol. 37): C563-C571, 1995.
14. Pohl, J., S. J. Winder, B. G. Allen, M. P. Walsh, J. R. Sellers, and W. T. Gerthoffer. Phosphorylation of calponin in airway smooth muscle. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L115-L123, 1997.
15. Shen, X., M. F. Wu, R. S. Tepper, and S. J. Gunst. Mechanisms for the mechanical response of airway smooth muscle to length oscillation. J. Appl. Physiol. 83: 731-738, 1997.
16. Somlyo, A. V., and A. P. Somlyo. Intracellular signalling in vascular smooth muscle. Adv. Exp. Med. Biol. 346: 31-38, 1993.
17. Tepper, R. S., X. Shen, E. Bakan, and S. J. Gunst. Maximal airway response in mature and immature rabbits during tidal ventilation. J. Appl. Physiol. 79: 1190-1198, 1995.
18. Wang, Z.-L., F. M. Pavalko, and S. J. Gunst. Tyrosine phosphorylation of the dense plaque protein paxillin is regulated during smooth muscle contraction. Am. J. Physiol. 271 (Cell Physiol. 40): C1594-C1602, 1996.
19. Wang, Z. L., F. M. Pavalko, and S. J. Gunst. Tyrosine phosphorylation of paxillin in Ca-depleted canine tracheal smooth muscle strips during stimulation with acetylcholine (Abstract). Biophys. J. 70: A47, 1996.
20. Warner, D. O., and S. J. Gunst. Limitation of maximal broncho-constriction in dogs. Am. Rev. Respir. Dis. 145: 553-560, 1992.